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Related papers: A Geostatistical Framework for Combining Spatially…

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Model-based geostatistics (MBG) is a subfield of spatial statistics focused on predicting spatially continuous phenomena using data collected at discrete locations. Geostatistical models often rely on the assumptions of stationarity and…

Methodology · Statistics 2024-12-13 Olatunji Johnson , Bedilu A Ejigu , Ezra Gayawan

Automated malaria diagnosis is a difficult but high-value target for machine learning (ML), and effective algorithms could save many thousands of children's lives. However, current ML efforts largely neglect crucial use case constraints and…

Machine Learning · Computer Science 2023-07-06 Charles B. Delahunt , Noni Gachuhi , Matthew P. Horning

Malaria remains a significant global health challenge, necessitating rapid and accurate diagnostic methods. While computer-aided diagnosis (CAD) tools utilizing deep learning have shown promise, their generalization to diverse clinical…

The problem of choosing spatial sampling designs for investigating unobserved spatial phenomenon S arises in many contexts, for example in identifying households to select for a prevalence survey to study disease burden and heterogeneity in…

Methodology · Statistics 2016-05-03 Michael G. Chipeta , Dianne J. Terlouw , Kamija S. Phiri , Peter J. Diggle

This dissertation is based on a project co-founded by the Health Market Quality Program (now Rozetta Institute) and the Australian Institute of Health and Welfare. The overall objective of this work is to provide a framework and a tool for…

Applications · Statistics 2023-04-18 Ludovico Pinzari

Prediction of the progression of an infectious disease outbreak is important for planning and coordinating a response. Differential equations are often used to model an epidemic outbreak's behaviour but are challenging to parameterise.…

Populations and Evolution · Quantitative Biology 2022-03-16 David Wu , Helen Petousis-Harris , Janine Paynter , Vinod Suresh , Oliver J. Maclaren

Missing data is a common problem in medical research, and is commonly addressed using multiple imputation. Although traditional imputation methods allow for valid statistical inference when data are missing at random (MAR), their…

Malaria transmission in Madagascar is highly heterogeneous, exhibiting spatial, seasonal and long-term trends. Previous efforts to map malaria risk in Madagascar used prevalence data from Malaria Indicator Surveys. These cross-sectional…

Longitudinal medical images are essential for monitoring disease progression by capturing spatiotemporal changes associated with dynamic biological processes. While current methods have made progress in modeling spatiotemporal patterns,…

Quantitative Methods · Quantitative Biology 2025-09-15 Shuaitong Zhang , Yuchen Sun , Yong Ao , Xuehuan Zhang , Ruoshui Yang , Jiantao Xu , Zuwu Ai , Haike Zhang , Xiang Yang , Yao Xu , Kunwei Li , Duanduan Chen

Spatial aggregation with respect to a population distribution involves estimating aggregate quantities for a population based on an observation of individuals in a subpopulation. In this context, a geostatistical workflow must account for…

Methodology · Statistics 2022-07-15 John Paige , Geir-Arne Fuglstad , Andrea Riebler , Jon Wakefield

Metric graphs are useful tools for describing spatial domains like road and river networks, where spatial dependence act along the network. We take advantage of recent developments for such Gaussian Random Fields (GRFs), and consider joint…

Malaria is an infectious disease affecting a large population across the world, and interventions need to be efficiently applied to reduce the burden of malaria. We develop a framework to help policy-makers decide how to allocate limited…

Applications · Statistics 2020-03-12 Qian Guan , Brian J. Reich , Eric B. Laber

There is an increasing focus on reducing inequalities in health outcomes in developing countries. Subnational variation is of particular interest, with geographic data used to understand the spatial risk of detrimental outcomes and to…

Methodology · Statistics 2020-12-22 Neal Marquez , Jon Wakefield

To date, we have seen the emergence of a large literature on multivariate disease mapping. That is, incidence of (or mortality from) multiple diseases is recorded at the scale of areal units where incidence (mortality) across the diseases…

Methodology · Statistics 2026-04-17 Garazi Retegui , María Dolores Ugarte , Jaione Etxeberria , Alan E. Gelfand

Non-gaussian spatial data are very common in many disciplines. For instance, count data are common in disease mapping, and binary data are common in ecology. When fitting spatial regressions for such data, one needs to account for…

Methodology · Statistics 2010-12-01 John Hughes , Murali Haran

In almost any geostatistical analysis, one of the underlying, often implicit, modelling assump- tions is that the spatial locations, where measurements are taken, are recorded without error. In this study we develop geostatistical inference…

Applications · Statistics 2017-11-02 Claudio Fronterrè , Emanuele Giorgi , Peter J. Diggle

Spatial connectivity is an important consideration when modelling infectious disease data across a geographical region. Connectivity can arise for many reasons, including shared characteristics between regions, and human or vector movement.…

Methodology · Statistics 2022-06-06 Sophie A Lee , Theodoros Economou , Rachel Lowe

In low- and middle-income countries (LMICs), accurate estimates of subnational health and demographic indicators are critical for guiding policy and identifying disparities. Many indicators of interest are proportions of binary outcomes and…

Applications · Statistics 2025-06-23 Jon Wakefield , Peter A. Gao , Geir-Arne Fuglstad , Zehang Richard Li

Regional aggregates of health outcomes over delineated administrative units (e.g., states, counties, zip codes), or areal units, are widely used by epidemiologists to map mortality or incidence rates and capture geographic variation. To…

Methodology · Statistics 2022-05-03 Leiwen Gao , Sudipto Banerjee , Beate Ritz

Disease mapping focuses on learning about areal units presenting high relative risk. Disease mapping models for disease counts specify Poisson regressions in relative risks compared with the expected counts. These models typically…

Methodology · Statistics 2016-07-26 Feifei Wang , Jian Wang , Alan E. Gelfand , Fan Li