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Targeted Radionuclide Therapy (TRT) is a modern strategy in radiation oncology that aims to administer a potent radiation dose specifically to cancer cells using cancer-targeting radiopharmaceuticals. Accurate radiation dose estimation…

Medical Physics · Physics 2025-09-15 Jing Zhang , Alexandre Bousse , Chi-Hieu Pham , Kuangyu Shi , Julien Bert

Computed Tomography (CT) imposes risk on the patients due to its inherent X-ray radiation, stimulating the development of low-dose CT (LDCT) imaging methods. Lowering the radiation dose reduces the health risks but leads to noisier…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Elvira Zainulina , Alexey Chernyavskiy , Dmitry V. Dylov

Deep learning (DL) has emerged as a tool for improving accelerated MRI reconstruction. A common strategy among DL methods is the physics-based approach, where a regularized iterative algorithm alternating between data consistency and a…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Burhaneddin Yaman , Seyed Amir Hossein Hosseini , Steen Moeller , Jutta Ellermann , Kâmil Uǧurbil , Mehmet Akçakaya

In the intention of minimizing excessive X-ray radiation administration to patients, low-dose computed tomography (LDCT) has become a distinct trend in radiology. However, while lowering the radiation dose reduces the risk to the patient,…

Medical Physics · Physics 2022-04-12 Long Zhou , Xiaozhuang Wang , Min Hou , Ping Li , Chunlong Fu , Yanjun Ren , Tingting Shao , Xi Hu , Jihong Sun , Hongwei Ye

Deep convolutional neural networks have shown outstanding performance in medical image segmentation tasks. The usual problem when training supervised deep learning methods is the lack of labeled data which is time-consuming and costly to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Suman Sedai , Bhavna Antony , Ravneet Rai , Katie Jones , Hiroshi Ishikawa , Joel Schuman , Wollstein Gadi , Rahil Garnavi

Deep-learning methods have shown promising performance for low-dose computed tomography (LDCT) reconstruction. However, supervised methods face the problem of lacking labeled data in clinical scenarios, and the CNN-based unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Ran An , Ke Chen , Hongwei Li

Low-Dose Computed Tomography (LDCT) technique, which reduces the radiation harm to human bodies, is now attracting increasing interest in the medical imaging field. As the image quality is degraded by low dose radiation, LDCT exams require…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Liutao Yang , Zhongnian Li , Rongjun Ge , Junyong Zhao , Haipeng Si , Daoqiang Zhang

Deep learning based PET image reconstruction methods have achieved promising results recently. However, most of these methods follow a supervised learning paradigm, which rely heavily on the availability of high-quality training labels. In…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Rui Hu , Yunmei Chen , Kyungsang Kim , Marcio Aloisio Bezerra Cavalcanti Rockenbach , Quanzheng Li , Huafeng Liu

Assume you encounter an inverse problem that shall be solved for a large number of data, but no ground-truth data is available. To emulate this encounter, in this study, we assume it is unknown how to solve the imaging problem of Computed…

Low-dose CT (LDCT) imaging is desirable in many clinical applications to reduce X-ray radiation dose to patients. Inspired by deep learning (DL), a recent promising direction of model-based iterative reconstruction (MBIR) methods for LDCT…

Image and Video Processing · Electrical Eng. & Systems 2021-02-18 Qiaoqiao Ding , Yuesong Nan , Hao Gao , Hui Ji

Deep learning (DL) has shown promise for faster, high quality accelerated MRI reconstruction. However, supervised DL methods depend on extensive amounts of fully-sampled (labeled) data and are sensitive to out-of-distribution (OOD) shifts,…

Partially-supervised learning can be challenging for segmentation due to the lack of supervision for unlabeled structures, and the methods directly applying fully-supervised learning could lead to incompatibility, meaning ground truth is…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Ke Zhang , Xiahai Zhuang

Training deep neural networks requires massive amounts of training data, but for many tasks only limited labeled data is available. This makes weak supervision attractive, using weak or noisy signals like the output of heuristic methods or…

Machine Learning · Computer Science 2017-12-08 Mostafa Dehghani , Aliaksei Severyn , Sascha Rothe , Jaap Kamps

Deep learning (DL) has arguably emerged as the method of choice for the detection and segmentation of biological structures in microscopy images. However, DL typically needs copious amounts of annotated training data that is for biomedical…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Mangal Prakash , Tim-Oliver Buchholz , Manan Lalit , Pavel Tomancak , Florian Jug , Alexander Krull

Dual-energy computed tomography (DECT) enables material-specific imaging through acquisitions at two different X-ray energy spectra. Material decomposition from DECT data is an ill-posed inverse problem that is highly sensitive to noise…

Low-dose computed tomography (LDCT) image reconstruction techniques can reduce patient radiation exposure while maintaining acceptable imaging quality. Deep learning is widely used in this problem, but the performance of testing data…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Kecheng Chen , Jie Liu , Renjie Wan , Victor Ho-Fun Lee , Varut Vardhanabhuti , Hong Yan , Haoliang Li

Long lasting efforts have been made to reduce radiation dose and thus the potential radiation risk to the patient for computed tomography acquisitions without severe deterioration of image quality. To this end, numerous reconstruction and…

Medical Physics · Physics 2024-10-07 Elias Eulig , Björn Ommer , Marc Kachelrieß

In order to reduce the potential radiation risk, low-dose CT has attracted more and more attention. However, simply lowering the radiation dose will significantly degrade the imaging quality. In this paper, we propose a noise reduction…

Medical Physics · Physics 2016-09-28 Hu Chen , Yi Zhang , Weihua Zhang , Peixi Liao , Ke Li , Jiliu Zhou , Ge Wang

Effective convolutional neural networks are trained on large sets of labeled data. However, creating large labeled datasets is a very costly and time-consuming task. Semi-supervised learning uses unlabeled data to train a model with higher…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Mehdi Sajjadi , Mehran Javanmardi , Tolga Tasdizen

Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Atul Padole , Fatemeh Homayounieh , Uwe Kruger , Ruhani Doda Khera , Chayanin Nitiwarangkul , Mannudeep K. Kalra , Ge Wang