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The generalized Lotka-Volterra (gLV) equations are a mathematical proxy for ecological dynamics. We focus on a gLV model of the gut microbiome, in which the evolution of the gut microbial state is determined in part by pairwise…

Populations and Evolution · Quantitative Biology 2020-05-13 Zipeng Wang , Eric W. Jones , Joshua M. Mueller , Jean M. Carlson

The generalized Lotka-Volterra (gLV) equations model the microbiome as a collection of interacting ecological species. Here we use a particular experimentally-derived gLV model of C. difficile infection (CDI) as a case study to generate…

Populations and Evolution · Quantitative Biology 2020-07-24 Eric W. Jones , Parker Shankin-Clarke , Jean M. Carlson

The state space is a fundamental concept for describing the trajectory of a dynamic system. Depending on its form, it can highlight certain changes over time while ignoring others. This is particularly the case for the spaces associated…

Dynamical Systems · Mathematics 2026-04-10 Arthur Doliveira , Christophe Roman , Guillaume Graton , Mustapha Ouladsine

Inferring microbial community structure based on temporal metagenomics data is an important goal in microbiome studies. The deterministic generalized Lotka-Volterra differential (GLV) equations have been used to model the dynamics of…

Methodology · Statistics 2020-09-24 Libai Xu , Ximing Xu , Dehan Kong , Hong Gu , Toby Kenney

We investigate the Generalized Lotka-Volterra (GLV) equations, a central model in theoretical ecology, where species interactions are assumed to be fixed over time and heterogeneous (quenched noise). Recent studies have suggested that the…

Populations and Evolution · Quantitative Biology 2023-06-26 Sandro Azaele , Amos Maritan

The generalized Lotka-Volterra (GLV) equations with quenched random interactions have been extensively used to investigate the stability and dynamics of complex ecosystems. However, the standard linear interaction model suffers from…

Populations and Evolution · Quantitative Biology 2026-02-03 Marco Zenari , Francesco Ferraro , Sandro Azaele , Amos Maritan , Samir Suweis

In this work, we explore the dynamics of species abundances within ecological communities using the Generalized Lotka-Volterra (GLV) model. At variance with previous approaches, we present an analysis of stochastic GLV dynamics with…

Populations and Evolution · Quantitative Biology 2024-04-24 Samir Suweis , Francesco Ferraro , Christian Grilletta , Sandro Azaele , Amos Maritan

Classical approaches to ecological stability rely on fully connected interaction models, yet real ecosystems are sparse and structured--a feature that qualitatively reshapes their collective dynamics. Here, we establish a thermodynamically…

Disordered Systems and Neural Networks · Physics 2025-12-30 Mattia Tarabolo , Luca Dall'Asta , Roberto Mulet

Complex system stability can be studied via linear stability analysis using Random Matrix Theory (RMT) or via feasibility (requiring positive equilibrium abundances). Both approaches highlight the importance of interaction structure. Here…

Populations and Evolution · Quantitative Biology 2023-05-17 Xiaoyuan Liu , George W. A. Constable , Jonathan W. Pitchford

Metagenomic data has significantly advanced microbiome research by employing ecological models, particularly in personalised medicine. The generalised Lotka-Volterra (gLV) model is commonly used to understand microbial interactions and…

Populations and Evolution · Quantitative Biology 2025-10-07 Mario Castro , Rafael Vida , Javier Galeano , José A. Cuesta

We are interested in the long time behavior of a two-type density-dependent biological population conditioned to non-extinction, in both cases of competition or weak cooperation between the two species. This population is described by a…

Probability · Mathematics 2008-11-04 Patrick Cattiaux , Sylvie Méléard

Systems of interacting species, such as biological environments or chemical reactions, are often described mathematically by sets of coupled ordinary differential equations. While a large number $\beta$ of species may be involved in the…

Dynamical Systems · Mathematics 2024-01-17 Rebecca E. Morrison

Populations of competing biological species exhibit a fascinating interplay between the nonlinear dynamics of evolutionary selection forces and random fluctuations arising from the stochastic nature of the interactions. The processes…

Populations and Evolution · Quantitative Biology 2012-05-08 A. Dobrinevski , E. Frey

This paper is devoted to the stability analysis of an n species Lotka-Volterra system with discrete and distributed delays. Stochastic perturbations to the parameters of the model are allowed. Sufficient conditions for the almost sure…

Classical Analysis and ODEs · Mathematics 2020-01-30 Krisztina Kiss , Eva Gyurkovics

Lotka-Volterra (LV) equations play a key role in the mathematical modeling of various ecological, biological and chemical systems. When the number of species (or, depending on the viewpoint, chemical components) becomes large, basic but…

Probability · Mathematics 2022-05-03 Maxime Clenet , François Massol , Jamal Najim

Spatial evolution is investigated in a simulated system of nine competing and mutating bacterium strains, which mimics the biochemical war among bacteria capable of producing two different bacteriocins (toxins) at most. Random sequential…

Statistical Mechanics · Physics 2009-10-31 Gyorgy Szabo , Tamas Czaran

Real ecosystems are characterized by sparse and asymmetric interactions, posing a major challenge to theoretical analysis. We introduce a new method to study the generalized Lotka-Volterra model with stochastic dynamics on sparse graphs. By…

Populations and Evolution · Quantitative Biology 2026-05-05 David Machado , Pietro Valigi , Tommaso Tonolo , Maria Chiara Angelini

In this paper we elaborate on the structure of the Generalized Lotka-Volterra (GLV) form for nonlinear differential equations. We discuss here the algebraic properties of the GLV family, such as the invariance under quasimonomial…

Biological Physics · Physics 2019-10-31 Benito Hernández-Bermejo , V. Fairén

How do interactions between species influence their spatial distribution in an ecosystem? To answer this question, we introduce a spatially-extended ecosystem of Generalized Lotka-Volterra type, where species can diffuse and interactions…

Statistical Mechanics · Physics 2025-01-08 Alessandro Salvatore , Fabián Aguirre-López , Ruben Zakine

Species-rich ecosystems often exhibit multiple stable states with distinct species compositions. Yet, the factors determining the likelihood of each state's occurrence remain poorly understood. Here, we characterize and explain the…

Populations and Evolution · Quantitative Biology 2025-11-11 Nitesh Kumar Patro , Washington Taylor , Akshit Goyal
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