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Recent advances in neural recording technology allow simultaneously recording action potentials from hundreds to thousands of neurons in awake, behaving animals. However, characterizing spike patterns in the resulting data, and linking…

The hand, a complex effector comprising dozens of degrees of freedom of movement, endows us with the ability to flexibly, precisely, and effortlessly interact with objects. The neural signals associated with dexterous hand movements in…

Neurons and Cognition · Quantitative Biology 2019-06-21 Elizaveta V. Okorokova , James M. Goodman , Nicholas G. Hatsopoulos , Sliman J. Bensmaia

Accurate finger force estimation is critical for next-generation human-machine interfaces. Traditional electromyography (EMG)-based decoding methods using deep learning require large datasets and high computational resources, limiting their…

Neural and Evolutionary Computing · Computer Science 2025-08-01 Farah Baracat , Giacomo Indiveri , Elisa Donati

Neural decoding plays a vital role in the interaction between the brain and the outside world. In this paper, we directly decode the movement track of a finger based on the neural signals of a macaque. Supervised regression methods may…

Neural and Evolutionary Computing · Computer Science 2025-10-14 Jingyi Feng , Yong Luo , Shuang Song

The Ising Model has recently received much attention for the statistical description of neural spike train data. In this paper, we propose and demonstrate its use for building decoders capable of predicting, on a millisecond timescale, the…

Neurons and Cognition · Quantitative Biology 2011-05-24 Michael T. Schaub , Simon R. Schultz

Understanding how neurons coordinate their activity is a fundamental question in neuroscience, with implications for learning, memory, and neurological disorders. Calcium imaging has emerged as a powerful method to observe large-scale…

Methodology · Statistics 2026-03-03 Laura D'Angelo , Francesco Denti , Antonio Canale , Michele Guindani

In this paper, the authors report a way to use concepts from statistical learning to gain an advantage in terms of error exponents while communicating over a discrete memoryless channel. The study utilizes the simulation capability of the…

Information Theory · Computer Science 2022-08-09 Aman Chawla , Salvatore Domenic Morgera

We investigate the sparse functional identification of complex cells and the decoding of visual stimuli encoded by an ensemble of complex cells. The reconstruction algorithm of both temporal and spatio-temporal stimuli is formulated as a…

Neurons and Cognition · Quantitative Biology 2017-06-20 Aurel A. Lazar , Nikul H. Ukani , Yiyin Zhou

Consider a compound Poisson process with jump measure $\nu$ supported by finitely many positive integers. We propose a method for estimating $\nu$ from a single, equidistantly sampled trajectory and develop associated statistical…

Statistics Theory · Mathematics 2009-09-29 Werner Ehm , Benjamin Staude , Stefan Rotter

Surface electromyography (sEMG) has demonstrated significant potential in simultaneous and proportional control (SPC). However, existing algorithms for predicting joint angles based onsEMGoften suffer fromhigh inference costs or are limited…

Human-Computer Interaction · Computer Science 2025-01-27 Xin Zhou , Chuang Lin , Can Wang , Xiaojiang Peng

The performance of upper-limb prostheses is currently limited by the relatively poor functionality of unintuitive control schemes. This paper proposes to extract, from multichannel electromyographic signals (EMG), motor neuron spike trains…

Signal Processing · Electrical Eng. & Systems 2019-10-22 Arash Andalib , Dario Farina , Ivan Vujaklija , Francesco Negro , Oskar C Aszmann , Rizwan Bashirullah , Jose C Principe

Objective: Sparse Bayesian learning provides an effective scheme to solve the high-dimensional problem in brain signal decoding. However, traditional assumptions regarding data distributions such as Gaussian and binomial are potentially…

Signal Processing · Electrical Eng. & Systems 2025-08-19 Yuanhao Li , Badong Chen , Wenjun Bai , Yasuharu Koike , Okito Yamashita

Electroencephalography (EEG)-based P300 brain-computer interfaces (BCIs) enable communication without physical movement by detecting stimulus-evoked neural responses. Accurate and efficient decoding remains challenging due to high…

Methodology · Statistics 2026-03-02 Guoxuan Ma , Yuan Zhong , Moyan Li , Yuxiao Nie , Jian Kang

For the past few years, we have developed flexible, active, multiplexed recording devices for high resolution recording over large, clinically relevant areas in the brain. While this technology has enabled a much higher-resolution view of…

Neurons and Cognition · Quantitative Biology 2017-06-06 Yilin Song , Jonathan Viventi , Yao Wang

Neural metrics have achieved impressive correlation with human judgements in the evaluation of machine translation systems, but before we can safely optimise towards such metrics, we should be aware of (and ideally eliminate) biases toward…

Computation and Language · Computer Science 2022-09-27 Chantal Amrhein , Rico Sennrich

The problem of deciphering how low-level patterns (action potentials in the brain, amino acids in a protein, etc.) drive high-level biological features (sensorimotor behavior, enzymatic function) represents the central challenge of…

Quantitative Methods · Quantitative Biology 2019-11-21 Damián G. Hernández , Samuel J. Sober , Ilya Nemenman

Ensemble of predictions is known to perform better than individual predictions taken separately. However, for tasks that require heavy computational resources, e.g. semantic segmentation, creating an ensemble of learners that needs to be…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Walid Bousselham , Guillaume Thibault , Lucas Pagano , Archana Machireddy , Joe Gray , Young Hwan Chang , Xubo Song

Hemispheric strokes impair motor control in contralateral body parts, necessitating effective rehabilitation strategies. Motor Imagery-based Brain-Computer Interfaces (MI-BCIs) promote neuroplasticity, aiding the recovery of motor…

Signal Processing · Electrical Eng. & Systems 2025-01-06 Praveen K. Parashiva , Sagila Gangadaran , A. P. Vinod

We consider the problem of predicting eye movement goals from local field potentials (LFP) recorded through a multielectrode array in the macaque prefrontal cortex. The monkey is tasked with performing memory-guided saccades to one of eight…

Neural and Evolutionary Computing · Computer Science 2019-01-30 Marko Angjelichinoski , Taposh Banerjee , John Choi , Bijan Pesaran , Vahid Tarokh

Modern well-performing approaches to neural decoding are based on machine learning models such as decision tree ensembles and deep neural networks. The wide range of algorithms that can be utilized to learn from neural spike trains, which…

Neurons and Cognition · Quantitative Biology 2023-01-30 Ivan Lazarevich , Ilya Prokin , Boris Gutkin , Victor Kazantsev