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Wide-field calcium imaging (WFCI) that records neural calcium dynamics allows for identification of functional brain networks (FBNs) in mice that express genetically encoded calcium indicators. Estimating FBNs from WFCI data is commonly…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Xiaohui Zhang , Eric C Landsness , Lindsey M Brier , Wei Chen , Michelle J. Tang , Hanyang Miao , Jin-Moo Lee , Mark A. Anastasio , Joseph P. Culver

Independent Component Analysis (ICA) offers interpretable semantic components of embeddings. While ICA theory assumes that embeddings can be linearly decomposed into independent components, real-world data often do not satisfy this…

Computation and Language · Computer Science 2024-10-10 Momose Oyama , Hiroaki Yamagiwa , Hidetoshi Shimodaira

Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

Machine Learning · Statistics 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

Recent research in neuroimaging has focused on assessing associations between genetic variants that are measured on a genomewide scale and brain imaging phenotypes. A large number of works in the area apply massively univariate analyses on…

In the high-dimensional landscape, addressing the challenges of covariance regression with high-dimensional covariates has posed difficulties for conventional methodologies. This paper addresses these hurdles by presenting a novel approach…

Methodology · Statistics 2024-04-11 Yuheng He , Changliang Zou , Yi Zhao

Background: Coronary angiography (CAG) is a cornerstone imaging modality for assessing coronary artery disease and guiding interventional treatment decisions. However, in real-world clinical settings, angiographic images are often…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Jingsong Xia , Siqi Wang

The statistical dependencies which independent component analysis (ICA) cannot remove often provide rich information beyond the linear independent components. It would thus be very useful to estimate the dependency structure from data.…

Machine Learning · Statistics 2017-07-28 Hiroaki Sasaki , Michael U. Gutmann , Hayaru Shouno , Aapo Hyvärinen

The concept of biological age (BA), although important in clinical practice, is hard to grasp mainly due to the lack of a clearly defined reference standard. For specific applications, especially in pediatrics, medical image data are used…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Karim Armanious , Sherif Abdulatif , Wenbin Shi , Shashank Salian , Thomas Küstner , Daniel Weiskopf , Tobias Hepp , Sergios Gatidis , Bin Yang

How will my face look when I get older? Or, for a more challenging question: How will my brain look when I get older? To answer this question one must devise (and learn from data) a multivariate auto-regressive function which given an image…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Tian Xia , Agisilaos Chartsias , Chengjia Wang , Sotirios A. Tsaftaris

A full parametric and linear specification may be insufficient to capture complicated patterns in studies exploring complex features, such as those investigating age-related changes in brain functional abilities. Alternatively, a partially…

Methodology · Statistics 2024-02-07 Jia Liang , Shuo Chen , Peter Kochunov , L Elliot Hong , Chixiang Chen

Encoding models provide a powerful framework for linking continuous stimulus features to neural activity; however, traditional voxelwise approaches are limited by measurement noise, inter-subject variability, and redundancy arising from…

Computation and Language · Computer Science 2026-04-29 Kamya Hari , Taha Binhuraib , Jin Li , Cory Shain , Anna A. Ivanova

Several brain disorders can be detected by observing alterations in the brain's structural and functional connectivities. Neurological findings suggest that early diagnosis of brain disorders, such as mild cognitive impairment (MCI), can…

Neurons and Cognition · Quantitative Biology 2021-10-22 Alpay Tekin , Ahmed Nebli , Islem Rekik

Mild cognitive impairment(MCI) is a precursor of Alzheimer's disease(AD), and the detection of MCI is of great clinical significance. Analyzing the structural brain networks of patients is vital for the recognition of MCI. However, the…

Neurons and Cognition · Quantitative Biology 2022-08-19 Heng Kong , Shuqiang Wang

The infant brain undergoes rapid development in the first few years after birth.Compared to cross-sectional studies, longitudinal studies can depict the trajectories of infants brain development with higher accuracy, statistical power and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Zihao Zhu , Tianli Tao , Yitian Tao , Haowen Deng , Xinyi Cai , Gaofeng Wu , Kaidong Wang , Haifeng Tang , Lixuan Zhu , Zhuoyang Gu , Jiawei Huang , Dinggang Shen , Han Zhang

Brain network provides important insights for the diagnosis of many brain disorders, and how to effectively model the brain structure has become one of the core issues in the domain of brain imaging analysis. Recently, various computational…

Neurons and Cognition · Quantitative Biology 2022-12-02 Zhengwang Xia , Tao Zhou , Saqib Mamoon , Amani Alfakih , Jianfeng Lu

We consider analysis of dependent functional data that are correlated because of a longitudinal-based design: each subject is observed at repeated time visits and for each visit we record a functional variable. We propose a novel…

Methodology · Statistics 2015-06-30 So Young Park , Ana-Maria Staicu

Now over 20 years old, functional MRI (fMRI) has a large and growing literature that is best synthesised with meta-analytic tools. As most authors do not share image data, only the peak activation coordinates (foci) reported in the paper…

Nonlinear independent component analysis (ICA) aims to uncover the true latent sources from their observable nonlinear mixtures. Despite its significance, the identifiability of nonlinear ICA is known to be impossible without additional…

Machine Learning · Computer Science 2023-11-03 Yujia Zheng , Kun Zhang

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Independent component analysis (ICA) is a fundamental data processing technique to decompose the captured signals into as independent as possible components. Computing the contrast function, which serves as a measure of independence of…

Quantum Physics · Physics 2023-11-22 Xiao-Fan Xu , Cheng Xue , Zhao-Yun Chen , Yu-Chun Wu , Guo-Ping Guo
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