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Interrogating the evolution of biological changes at early stages of life requires longitudinal profiling of molecules, such as DNA methylation, which can be challenging with children. We introduce a probabilistic and longitudinal machine…

Genomics · Quantitative Biology 2025-04-24 Arthur Leroy , Ai Ling Teh , Frank Dondelinger , Mauricio A. Alvarez , Dennis Wang

Breast cancer is the most common cancer in the world and the most prevalent cause of death among women worldwide. Nevertheless, it is also one of the most treatable malignancies if detected early. In this paper, a deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Hussin Ragb , Redha Ali , Elforjani Jera , Nagi Buaossa

Early detection is crucial for successful cancer treatment and increasing survivability rates, particularly in the most common forms. Ten different cancers have been identified in most of these advances that effectively use CNNs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Hossein Molaeian , Kaveh Karamjani , Sina Teimouri , Saeed Roshani , Sobhan Roshani

Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

The advent of digital pathology presents opportunities for computer vision for fast, accurate, and objective solutions for histopathological images and aid in knowledge discovery. This work uses deep learning to predict genomic biomarkers -…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Ruchi Chauhan , PK Vinod , CV Jawahar

Convolutional neural networks (CNNs) have shown great promise in improving computer aided detection (CADe). From classifying tumors found via mammography as benign or malignant to automated detection of colorectal polyps in CT colonography,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Hunter Park , Connor Monahan

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ha Anh Vu

Breast cancer is the most common cancer in women worldwide. The most common screening technology is mammography. To reduce the cost and workload of radiologists, we propose a computer aided detection approach for classifying and localizing…

Computer Vision and Pattern Recognition · Computer Science 2018-03-07 Pengcheng Xi , Chang Shu , Rafik Goubran

In this paper, we propose a Computer Assisted Diagnosis (CAD) system based on a deep Convolutional Neural Network (CNN) model, to build an end-to-end learning process that classifies breast mass lesions. We investigate the impact that has…

Computer Vision and Pattern Recognition · Computer Science 2017-11-30 Hiba Chougrad , Hamid Zouaki , Omar Alheyane

The automated detection of cancerous tumors has attracted interest mainly during the last decade, due to the necessity of early and efficient diagnosis that will lead to the most effective possible treatment of the impending risk. Several…

Image and Video Processing · Electrical Eng. & Systems 2023-10-13 Vasileios E. Papageorgiou , Pantelis Dogoulis , Dimitrios-Panagiotis Papageorgiou

Digitization of histopathology slides has led to several advances, from easy data sharing and collaborations to the development of digital diagnostic tools. Deep learning (DL) methods for classification and detection have shown great…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Apostolia Tsirikoglou , Karin Stacke , Gabriel Eilertsen , Martin Lindvall , Jonas Unger

\textbf{Background}: Identifying differentially methylated regions (DMRs) is a basic task in DNA methylation analysis. However, due to the different strategies adopted, different DMR sets will be predicted on the same dataset, which poses a…

Quantitative Methods · Quantitative Biology 2024-07-16 Wenjin Zhang , Wenlong Jie , Wanxin Cui , Guihua Duan , You zou , Xiaoqing Peng

Computer Aided Diagnosis has emerged as an indispensible technique for validating the opinion of radiologists in CT interpretation. This paper presents a deep 3D Convolutional Neural Network (CNN) architecture for automated CT scan-based…

Image and Video Processing · Electrical Eng. & Systems 2019-06-05 Sumita Mishra , Naresh Kumar Chaudhary , Pallavi Asthana , Anil Kumar

Advances in deep learning for natural images have prompted a surge of interest in applying similar techniques to medical images. The majority of the initial attempts focused on replacing the input of a deep convolutional neural network with…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Krzysztof J. Geras , Stacey Wolfson , Yiqiu Shen , Nan Wu , S. Gene Kim , Eric Kim , Laura Heacock , Ujas Parikh , Linda Moy , Kyunghyun Cho

Objective: This paper proposes a deep learning model for breast cancer detection from reconstructed images of microwave imaging scan data and aims to improve the accuracy and efficiency of breast tumor detection, which could have a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-21 Gayathri Girish , Ponnathota Spandana , Badrish Vasu

The Deep learning (DL) models for diagnosing breast cancer from mammographic images often operate as "black boxes", making it difficult for healthcare professionals to trust and understand their decision-making processes. The study presents…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Maryam Ahmed , Tooba Bibi , Rizwan Ahmed Khan , Sidra Nasir

In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics. One key problem is to identify aberrant patterns of these processes and…

Applications · Statistics 2012-10-03 Matthias Kormaksson , James G. Booth , Maria E. Figueroa , Ari Melnick

In DNA computing, it is impossible to decide whether a specific hybridization among complex DNA molecules is effective or not within acceptable time. In order to address this common problem, we introduce a new method based on the machine…

Quantitative Methods · Quantitative Biology 2018-07-03 Weijun Zhu

By combining various cancer cell line (CCL) drug screening panels, the size of the data has grown significantly to begin understanding how advances in deep learning can advance drug response predictions. In this paper we train >35,000…

DNA cytosine methylation is a critical epigenetic mark regulating gene expression and thus playing an important role in development and differentiation across eukaryotes. Existing tools for high-throughput methylation analysis often lack…

Other Quantitative Biology · Quantitative Biology 2025-10-29 Jonas Bucher , Ueli Grossniklaus , Deepak Kumar Tanwar
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