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Long cell protrusions, which are effectively one-dimensional, are highly dynamic subcellular structures. Length of many such protrusions keep fluctuating about the mean value even in the the steady state. We develop here a stochastic model…

Subcellular Processes · Quantitative Biology 2021-08-31 Swayamshree Patra , Debashish Chowdhury

Automated identification of insects is a tough task where many challenges like data limitation, imbalanced data count, and background noise needs to be overcome for better performance. This paper describes such an image dataset which…

Multimedia · Computer Science 2021-01-28 D. L. Abeywardhana , C. D. Dangalle , Anupiya Nugaliyadde , Yashas Mallawarachchi

Rapid identification of bacterial species is crucial in medicine and food hygiene. In order to achieve rapid and label-free identification of bacterial species at the single bacterium level, we propose and experimentally demonstrate an…

Foraminifera are single-celled marine organisms, which may have a planktic or benthic lifestyle. During their life cycle they construct shells consisting of one or more chambers, and these shells remain as fossils in marine sediments.…

Machine Learning · Computer Science 2020-01-15 Thomas Haugland Johansen , Steffen Aagaard Sørensen

We report the cell biological applications of a recently developed multiphoton fluorescence lifetime imaging microscopy system using a streak camera (StreakFLIM). The system was calibrated with standard fluorophore specimens and was shown…

Cell Behavior · Quantitative Biology 2009-11-10 R. V. Krishnan , Eva Biener , Jian-Hua Zhang , Robert Heckel , Brian Herman

Ultrasound examination is widely used in the clinical diagnosis of thyroid nodules (benign/malignant). However, the accuracy relies heavily on radiologist experience. Although deep learning techniques have been investigated for thyroid…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yuchen Wang , Zhongyu Li , Xiangxiang Cui , Liangliang Zhang , Xiang Luo , Meng Yang , Shi Chang

This project investigates the human multi-modal behavior identification algorithm utilizing deep neural networks. According to the characteristics of different modal information, different deep neural networks are used to adapt to different…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jinyin Wang , Xingchen Li , Yixuan Jin , Yihao Zhong , Keke Zhang , Chang Zhou

The eukaryotic flagellum beats with apparently unfailing periodicity, yet responds rapidly to stimuli. Like the human heartbeat, flagellar oscillations are now known to be noisy. Using the alga \textit{C. reinhardtii}, we explore three…

Soft Condensed Matter · Physics 2014-12-03 Kirsty Y. Wan , Raymond E. Goldstein

Cilia and flagella exhibit regular bending waves that perform mechanical work on the surrounding fluid, to propel cellular swimmers and pump fluids inside organisms. Here, we quantify a force-velocity relationship of the beating flagellum,…

Cell Behavior · Quantitative Biology 2016-12-21 Gary S. Klindt , Christian Ruloff , Christian Wanger , Benjamin M. Friedrich

Single flagellated bacteria are ubiquitous in nature. They exhibit various swimming modes using their flagella to explore complex surroundings such as soil and porous polymer networks. Some single-flagellated bacteria swim with two distinct…

Soft Condensed Matter · Physics 2024-11-20 H. Gidituri , M. Ellero , F. Balboa Usabiaga

Harmful algae blooms (HABs), which produce lethal toxins, are a growing global concern since they negatively affect the quality of drinking water and have major negative impact on wildlife, the fishing industry, as well as tourism and…

Computer Vision and Pattern Recognition · Computer Science 2018-05-04 Jason L. Deglint , Chao Jin , Angela Chao , Alexander Wong

Traction Force Microscopy (TFM) is a technique used to determine the tensions that a biological cell conveys to the underlying surface. Typically, TFM requires culturing cells on gels with fluorescent beads, followed by bead displacement…

Image and Video Processing · Electrical Eng. & Systems 2019-10-17 Nicolas Pielawski , Jianjiang Hu , Staffan Strömblad , Carolina Wählby

Many swimming microorganisms, such as bacteria and sperm, use flexible flagella to move through viscoelastic media in their natural environments. In this paper we address the effects a viscoelastic fluid has on the motion and beating…

Soft Condensed Matter · Physics 2009-11-13 Henry C. Fu , Charles W. Wolgemuth , Thomas R. Powers

Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag…

Quantitative Methods · Quantitative Biology 2013-09-06 Thomas D. Montenegro-Johnson , Andrew A. Smith , David J. Smith , Daniel Loghin , John R. Blake

Flagellar-driven locomotion plays a critical role in bacterial attachment and colonization of surfaces, contributing to the risks of contamination and infection. Tremendous attempts to uncover the underlying principles governing bacterial…

Soft Condensed Matter · Physics 2025-02-19 Xin-Xin Xu , Yangguang Tian , Yuhe Pu , Bingchen Che , Hao Luo , Yanan Liu , Yan-Jun Liu , Guangyin Jing

The movement of the infective form of the T. Cruzi parasite within the human blood is not completely understood. Video microscopy observations confirm forward motility of the protozoa and relate it to the deformation of the body,…

Biological Physics · Physics 2025-10-27 Alberto-Mario Castillo , Gabriel Villalobos

The locomotion of microorganisms and spermatozoa in complex viscoelastic fluids is of critical importance in many biological processes such as fertilization, infection, and biofilm formation. Depending on their propulsion mechanisms,…

Soft Condensed Matter · Physics 2021-09-14 Gaojin Li , Eric Lauga , Arezoo M. Ardekani

Tracking cell particles in 3D microscopy videos is a challenging task but is of great significance for modeling the motion of cells. Proper characterization of the cell's shape, evolution, and their movement over time is crucial to…

Computer Vision and Pattern Recognition · Computer Science 2021-01-13 Mojtaba S. Fazli , Rachel V. Stadler , BahaaEddin Alaila , Stephen A. Vella , Silvia N. J. Moreno , Gary E. Ward , Shannon Quinn

Numerous studies have explored the link between bacterial swimming and the number of flagella, a distinguishing feature of motile multiflagellated bacteria. We revisit this open question using augmented slender-body theory simulations, in…

Biological Physics · Physics 2024-09-04 Maria Tătulea-Codrean , Eric Lauga

Analysis of microscope images is a tedious work which requires patience and time, usually done manually by the microscopist after data collection. Here we introduce an approach of automatic image analysis, which is based on locally applied…

Image and Video Processing · Electrical Eng. & Systems 2019-12-17 Benedykt R. Jany , Arkadiusz Janas , Franciszek Krok