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Accurate lesion detection in computer tomography (CT) slices benefits pathologic organ analysis in the medical diagnosis process. More recently, it has been tackled as an object detection problem using the Convolutional Neural Networks…

Computer Vision and Pattern Recognition · Computer Science 2019-07-10 Qingbin Shao , Lijun Gong , Kai Ma , Hualuo Liu , Yefeng Zheng

Multiple Sclerosis (MS) is a severe neurological disease characterized by inflammatory lesions in the central nervous system. Hence, predicting inflammatory disease activity is crucial for disease assessment and treatment. However, MS…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Chinmay Prabhakar , Hongwei Bran Li , Johannes C. Paetzold , Timo Loehr , Chen Niu , Mark Mühlau , Daniel Rueckert , Benedikt Wiestler , Bjoern Menze

This work presents a comparative study of existing and new techniques to detect knee injuries by leveraging Stanford's MRNet Dataset. All approaches are based on deep learning and we explore the comparative performances of transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 David Azcona , Kevin McGuinness , Alan F. Smeaton

Diabetic retinopathy is one of the leading causes of preventable blindness in the world. Its earliest sign are red lesions, a general term that groups both microaneurysms and hemorrhages. In daily clinical practice, these lesions are…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 José Ignacio Orlando , Elena Prokofyeva , Mariana del Fresno , Matthew B. Blaschko

Popular approaches for quantifying predictive uncertainty in deep neural networks often involve distributions over weights or multiple models, for instance via Markov Chain sampling, ensembling, or Monte Carlo dropout. These techniques…

Machine Learning · Computer Science 2023-03-08 Dennis Ulmer , Christian Hardmeier , Jes Frellsen

Background and objective: MeshCNN is a recently proposed Deep Learning framework that drew attention due to its direct operation on irregular, non-uniform 3D meshes. On selected benchmarking datasets, it outperformed state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Lisa Schneider , Annika Niemann , Oliver Beuing , Bernhard Preim , Sylvia Saalfeld

Automated surface segmentation is important and challenging in many medical image analysis applications. Recent deep learning based methods have been developed for various object segmentation tasks. Most of them are a classification based…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Leixin Zhou , Xiaodong Wu

Lesion detection is an important problem within medical imaging analysis. Most previous work focuses on detecting and segmenting a specialized category of lesions (e.g., lung nodules). However, in clinical practice, radiologists are…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Ke Yan , Jinzheng Cai , Adam P. Harrison , Dakai Jin , Jing Xiao , Le Lu

Dose escalation radiotherapy allows increased control of prostate cancer (PCa) but requires segmentation of dominant index lesions (DIL), motivating the development of automated methods for fast, accurate, and consistent segmentation of PCa…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Josiah Simeth , Jue Jiang , Anton Nosov , Andreas Wibmer , Michael Zelefsky , Neelam Tyagi , Harini Veeraraghavan

Localization of focal vascular lesions on brain MRI is an important component of research on the etiology of neurological disorders. However, manual annotation of lesions can be challenging, time-consuming and subject to observer bias.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Kimberlin M. H. van Wijnen , Florian Dubost , Pinar Yilmaz , M. Arfan Ikram , Wiro J. Niessen , Hieab Adams , Meike W. Vernooij , Marleen de Bruijne

The current multiple sclerosis (MS) diagnostic criteria lack specificity, and this may lead to misdiagnosis, which remains an issue in present-day clinical practice. In addition, conventional biomarkers only moderately correlate with MS…

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Neural networks for automated image segmentation are typically trained to achieve maximum accuracy, while less attention has been given to the calibration of their confidence scores. However, well-calibrated confidence scores provide…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Axel-Jan Rousseau , Thijs Becker , Jeroen Bertels , Matthew B. Blaschko , Dirk Valkenborg

The novel coronavirus disease 2019 (COVID-19) characterized by atypical pneumonia has caused millions of deaths worldwide. Automatically segmenting lesions from chest Computed Tomography (CT) is a promising way to assist doctors in COVID-19…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Yanwen Li , Luyang Luo , Huangjing Lin , Hao Chen , Pheng-Ann Heng

Quality control (QC) of MR images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually and subjectively, at significant time and operator cost.…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Richard Shaw , Carole H. Sudre , Sebastien Ourselin , M. Jorge Cardoso , Hugh G. Pemberton

Purpose: Accurate segmentation of glioma subregions in multi-parametric MRI (MP-MRI) is essential for diagnosis and treatment planning but remains challenging due to tumor heterogeneity and ambiguous boundaries. This study proposes an…

Medical Physics · Physics 2025-07-22 Zhenyu Yang , Chen Yang , Rihui Zhang , Minbin Chen , Chunhao Wang , Fang-Fang Yin

Unsupervised skin lesion segmentation offers several benefits, including conserving expert human resources, reducing discrepancies due to subjective human labeling, and adapting to novel environments. However, segmenting dermoscopic images…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Xiaofan Li , Bo Peng , Jie Hu , Changyou Ma , Daipeng Yang , Zhuyang Xie

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Lacunes of presumed vascular origin (lacunes) are associated with an increased risk of stroke, gait impairment, and dementia and are a primary imaging feature of the small vessel disease. Quantification of lacunes may be of great importance…