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Recently, deep feedforward neural networks have achieved considerable success in modeling biological sensory processing, in terms of reproducing the input-output map of sensory neurons. However, such models raise profound questions about…

Neurons and Cognition · Quantitative Biology 2019-12-16 Hidenori Tanaka , Aran Nayebi , Niru Maheswaranathan , Lane McIntosh , Stephen A. Baccus , Surya Ganguli

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Cortical neurons whose activity is recorded in behavioral experiments has been classified into several types such as stimulus-related neurons, delay-period neurons, and reward-related neurons. Moreover, the population activity of neurons…

Neurons and Cognition · Quantitative Biology 2018-11-27 Takuma Tanaka

Capsule networks (see e.g. Hinton et al., 2018) aim to encode knowledge and reason about the relationship between an object and its parts. In this paper we specify a \emph{generative} model for such data, and derive a variational algorithm…

Machine Learning · Computer Science 2022-03-16 Alfredo Nazabal , Nikolaos Tsagkas , Christopher K. I. Williams

To learn how cognition is implemented in the brain, we must build computational models that can perform cognitive tasks, and test such models with brain and behavioral experiments. Cognitive science has developed computational models of…

Neurons and Cognition · Quantitative Biology 2018-08-01 Nikolaus Kriegeskorte , Pamela K. Douglas

The brain constantly turns large flows of sensory information into selective representations of the environment. It, therefore, needs to learn to process those sensory inputs that are most relevant for behaviour. It is not well understood…

Neurons and Cognition · Quantitative Biology 2023-01-10 Pouya Baniasadi

Predictive coding has emerged as an influential normative model of neural computation, with numerous extensions and applications. As such, much effort has been put into mapping PC faithfully onto the cortex, but there are issues that remain…

Neurons and Cognition · Quantitative Biology 2023-03-07 Siavash Golkar , Tiberiu Tesileanu , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

This paper presents a highly speculative model encompassing the cortex, thalamus, and hippocampus of the mammalian brain. While the majority of computational neuroscience models are founded upon empirical evidence, this model is predicated…

Neurons and Cognition · Quantitative Biology 2024-05-22 Valentin Puente-Varona

A wide range of evidence points toward the existence of a common algorithm underlying the processing of information throughout the cerebral cortex. Several hypothesized features of this cortical algorithm are reviewed, including sparse…

Neurons and Cognition · Quantitative Biology 2014-11-19 Michael R. Ferrier

The thesis explores the role machine learning methods play in creating intuitive computational models of neural processing. Combined with interpretability techniques, machine learning could replace human modeler and shift the focus of human…

Neurons and Cognition · Quantitative Biology 2020-10-20 Ilya Kuzovkin

Computer vision tasks are difficult because of the large variability in the data that is induced by changes in light, background, partial occlusion as well as the varying pose, texture, and shape of objects. Generative approaches to…

Computer Vision and Pattern Recognition · Computer Science 2018-11-30 Adam Kortylewski , Mario Wieser , Andreas Morel-Forster , Aleksander Wieczorek , Sonali Parbhoo , Volker Roth , Thomas Vetter

Computational models lie at the intersection of basic neuroscience and healthcare applications because they allow researchers to test hypotheses \textit{in silico} and predict the outcome of experiments and interactions that are very hard…

Neurons and Cognition · Quantitative Biology 2020-09-18 Katharina Glomb , Joana Cabral , Anna Cattani , Alberto Mazzoni , Ashish Raj , Benedetta Franceschiello

Deducing the structure of neural circuits is one of the central problems of modern neuroscience. Recently-introduced calcium fluorescent imaging methods permit experimentalists to observe network activity in large populations of neurons,…

Applications · Statistics 2011-07-22 Yuriy Mishchencko , Joshua T. Vogelstein , Liam Paninski

Robust information representation and its persistent maintenance are fundamental for higher cognitive functions. Existing models employ distinct neural mechanisms to separately address noise-resistant processing or information maintenance,…

Neurons and Cognition · Quantitative Biology 2025-08-19 Jie Su , Weiwei Wang , Zhaotian Gu , Dahui Wang , Tianyi Qian

Cortical surface analysis has gained increased prominence, given its potential implications for neurological and developmental disorders. Traditional vision diffusion models, while effective in generating natural images, present limitations…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Zhenshan Xie , Simon Dahan , Logan Z. J. Williams , M. Jorge Cardoso , Emma C. Robinson

A substantial amount of time and energy has been invested to develop machine vision using connectionist (neural network) principles. Most of that work has been inspired by theories advanced by neuroscientists and behaviorists for how…

Neurons and Cognition · Quantitative Biology 2020-09-01 Ernest Greene

Feedforward CNN models have proven themselves in recent years as state-of-the-art models for predicting single-neuron responses to natural images in early visual cortical neurons. In this paper, we extend these models with recurrent…

Neural and Evolutionary Computing · Computer Science 2022-11-15 Yimeng Zhang , Harold Rockwell , Sicheng Dai , Ge Huang , Stephen Tsou , Yuanyuan Wei , Tai Sing Lee

Active inference is a theory that underpins the way biological agent's perceive and act in the real world. At its core, active inference is based on the principle that the brain is an approximate Bayesian inference engine, building an…

Artificial Intelligence · Computer Science 2020-03-09 Ozan Çatal , Samuel Wauthier , Tim Verbelen , Cedric De Boom , Bart Dhoedt

With recent and rapid advancements in artificial intelligence (AI), understanding the foundation of purposeful behaviour in autonomous agents is crucial for developing safe and efficient systems. While artificial neural networks have…

Artificial Intelligence · Computer Science 2025-08-12 Aswin Paul , Moein Khajehnejad , Forough Habibollahi , Brett J. Kagan , Adeel Razi

Deep generative models, while revolutionizing fields like image and text generation, largely operate as opaque ``black boxes'', hindering human understanding, control, and alignment. While methods like sparse autoencoders (SAEs) show…

Machine Learning · Computer Science 2026-04-03 Lingjing Kong , Shaoan Xie , Guangyi Chen , Yuewen Sun , Xiangchen Song , Eric P. Xing , Kun Zhang