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A Boolean network is a finite dynamical system, whose variables take values from a binary set. The value update rule for each variable is a Boolean function, depending on a selected subset of variables. Boolean networks have been widely…

Dynamical Systems · Mathematics 2017-08-10 Zuguang Gao , Xudong Chen , Tamer Başar

Real-world multi-agent systems are often dynamic and continuous, where the agents co-evolve and undergo changes in their trajectories and interactions over time. For example, the COVID-19 transmission in the U.S. can be viewed as a…

Machine Learning · Computer Science 2024-03-04 Zijie Huang , Jeehyun Hwang , Junkai Zhang , Jinwoo Baik , Weitong Zhang , Dominik Wodarz , Yizhou Sun , Quanquan Gu , Wei Wang

Boolean networks are special types of finite state time-discrete dynamical systems. A Boolean network can be described by a function from an n-dimensional vector space over the field of two elements to itself. A fundamental problem in…

Quantitative Methods · Quantitative Biology 2013-07-03 Yi Ming Zou

Networks serve as a tool used to examine the large-scale connectivity patterns in complex systems. Modelling their generative mechanism nonparametrically is often based on step-functions, such as the stochastic block models. These models…

Methodology · Statistics 2024-01-11 Arthur Verdeyme , Sofia C. Olhede

Unsupervised learning of latent variable models (LVMs) is widely used to represent data in machine learning. When such models reflect the ground truth factors and the mechanisms mapping them to observations, there is reason to expect that…

Machine Learning · Statistics 2023-01-23 Simon Buchholz , Michel Besserve , Bernhard Schölkopf

The regulation of the cell state is a complex process involving several components. These complex dynamics can be modeled using Boolean networks, allowing us to explain the existence of different cell states and the transition between them.…

Molecular Networks · Quantitative Biology 2010-01-28 Elke K. Markert , Nils Baas , Arnold J. Levine , Alexei Vazquez

Structural identifiability is a property of a differential model with parameters that allows for the parameters to be determined from the model equations in the absence of noise. The method of input-output equations is one method for…

Dynamical Systems · Mathematics 2022-01-28 Alexey Ovchinnikov , Gleb Pogudin , Peter Thompson

Features of the Jacobian matrix of the delay coordinates map are exploited for quantifying the robustness and reliability of state and parameter estimations for a given dynamical model using an observed time series. Relevant concepts of…

Chaotic Dynamics · Physics 2015-07-23 Ulrich Parlitz , Jan Schumann-Bischoff , Stefan Luther

This thesis aims at the logical analysis of discrete processes, in particular of such generated by gene regulatory networks. States, transitions and operators from temporal logics are expressed in the language of Formal Concept Analysis. By…

Molecular Networks · Quantitative Biology 2012-04-11 Johannes Wollbold

Boolean circuit is a computational graph that consists of the dynamic directed graph structure and static functionality. The commonly used logic optimization and Boolean matching-based transformation can change the behavior of the Boolean…

Machine Learning · Computer Science 2024-11-19 Liwei Ni , Xinquan Li , Biwei Xie , Huawei Li

The present status of the mapped interacting boson model studies on nuclear structure is reviewed. With the assumption that the nuclear surface deformation induced by the multi-nucleon dynamics is simulated by bosonic degrees of freedom,…

Nuclear Theory · Physics 2025-06-19 Kosuke Nomura

Different Boolean networks may reveal similar dynamics although their definition differs, then preventing their distinction from the observations. This raises the question about the sufficiency of a particular Boolean network for properly…

Discrete Mathematics · Computer Science 2014-11-25 Franck Delaplace

We consider a class of non-linear dynamics on a graph that contains and generalizes various models from network systems and control and study convergence to uniform agreement states using gradient methods. In particular, under the…

Dynamical Systems · Mathematics 2016-08-10 Herbert Mangesius , Jean-Charles Delvenne , Sanjoy K. Mitter

We propose a graphical notation by which certain spectral properties of complex systems can be rewritten concisely and interpreted topologically. Applying this notation to analyze the stability of a class of networks of coupled dynamical…

Adaptation and Self-Organizing Systems · Physics 2012-05-16 Anne-Ly Do , Stefano Boccaletti , Thilo Gross

We introduce a framework for analyzing ordinary differential equation (ODE) models of biological networks using statistical model checking (SMC). A key aspect of our work is the modeling of single-cell variability by assigning a probability…

Quantitative Methods · Quantitative Biology 2018-12-05 Bing Liu , Benjamin M. Gyori , P. S. Thiagarajan

The generating functional method is employed to investigate the synchronous dynamics of Boolean networks, providing an exact result for the system dynamics via a set of macroscopic order parameters. The topology of the networks studied and…

Disordered Systems and Neural Networks · Physics 2015-05-28 Alexander Mozeika , David Saad

The study of the interplay between the structure and dynamics of complex multilevel systems is a pressing challenge nowadays. In this paper, we use a semi-annealed approximation to study the stability properties of Random Boolean Networks…

Physics and Society · Physics 2012-10-31 Emanuele Cozzo , Alex Arenas , Yamir Moreno

Many biochemical processes can successfully be described by dynamical systems allowing some form of switching when, depending on their initial conditions, solutions of the dynamical system end up in different regions of state space…

Molecular Networks · Quantitative Biology 2011-09-27 Carsten Conradi , Dietrich Flockerzi

Genetic regulatory networks control ontogeny. For fifty years Boolean networks have served as models of such systems, ranging from ensembles of random Boolean networks as models for generic properties of gene regulation to working dynamical…

Molecular Networks · Quantitative Biology 2019-02-04 Stefan Bornholdt , Stuart Kauffman

Boolean networks have been successfully used in modelling gene regulatory networks. In this paper we propose a reduction method that reduces the complexity of a Boolean network but keeps dynamical properties and topological features and…

Quantitative Methods · Quantitative Biology 2009-07-06 Alan Veliz-Cuba