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Statistical models are often structurally unidentifiable, because different sets of parameters can lead to equal model outcomes. To be useful for prediction and parameter inference from data, stochastic population models need to be…

Populations and Evolution · Quantitative Biology 2025-03-19 Jose A. Capitan , David Alonso

A model of the dynamics of natural rotifer populations is described as a discrete nonlinear map depending on three parameters, which reflect characteristics of the population and environment. Model dynamics and their change by variation of…

Subcellular Processes · Quantitative Biology 2007-05-23 Faina S. Berezovskaya , Georgy P. Karev , Terry W. Snell

In this work, we revisit the classical Holling type II three species food chain model with a different viewpoint. Two critical parameters $\lambda_1$ and $\lambda_2$ dependent on other six parameters are defined. We show that local…

Dynamical Systems · Mathematics 2021-09-14 Kaijen Cheng , Hongming You , Ting-Hui Yang

Log-linear models are typically fitted to contingency table data to describe and identify the relationship between different categorical variables. However, the data may include observed zero cell entries. The presence of zero cell entries…

Methodology · Statistics 2022-12-01 Serveh Sharifi Far , Michail Papathomas , Ruth King

The ability to represent intracellular biochemical dynamics via deterministic and stochastic modelling is one of the crucial components to move biological sciences in the observe-predict-control-design knowledge ladder. Compared to the…

Quantitative Methods · Quantitative Biology 2013-03-14 Michał Włodarczyk , Tomasz Lipniacki , Michał Komorowski

Redundancy is a fundamental characteristic of many biological processes such as those in the genetic, visual, muscular and nervous system; yet its function has not been fully understood. The conventional interpretation of redundancy is that…

Information Theory · Computer Science 2019-02-04 Anh Tuan Nguyen , Jian Xu , Diu Khue Luu , Qi Zhao , Zhi Yang

Parameter inference and uncertainty quantification are important steps when relating mathematical models to real-world observations, and when estimating uncertainty in model predictions. However, methods for doing this can be…

Quantitative Methods · Quantitative Biology 2025-08-27 Michael J. Plank , Matthew J. Simpson

The Hessian of a neural network captures parameter interactions through second-order derivatives of the loss. It is a fundamental object of study, closely tied to various problems in deep learning, including model design, optimization, and…

Machine Learning · Computer Science 2021-07-02 Sidak Pal Singh , Gregor Bachmann , Thomas Hofmann

We study parametric inference on a rich class of hazard regression models in the presence of right-censoring. Previous literature has reported some inferential challenges, such as multimodal or flat likelihood surfaces, in this class of…

Methodology · Statistics 2023-05-10 F. J. Rubio , J. A. Espindola , J. A. Montoya

This study presents a new strategy for the identification of material parameters in the case of restricted or redundant data, based on a hybrid approach combining a genetic algorithm and the Levenberg-Marquardt method. The proposed…

Neural and Evolutionary Computing · Computer Science 2017-07-05 S. Carbillet , V. Guicheret-Retel , F. Trivaudey , F. Richard , M. L. Boubakar

Heterogeneity is a dominant factor in the behaviour of many biological processes. Despite this, it is common for mathematical and statistical analyses to ignore biological heterogeneity as a source of variability in experimental data.…

Understanding the links between diet, metabolic changes, and health outcomes is a key focus in nutritional science and broader biological research. Analyzing relationships, such as those between ultra-processed food (UPF) intake and…

Methodology · Statistics 2026-05-19 Sang Kyu Lee , Erikka Loftfield , Hyokyoung G. Hong , Haolei Weng

Recent research has shown the existence of significant redundancy in large Transformer models. One can prune the redundant parameters without significantly sacrificing the generalization performance. However, we question whether the…

Computation and Language · Computer Science 2022-02-15 Chen Liang , Haoming Jiang , Simiao Zuo , Pengcheng He , Xiaodong Liu , Jianfeng Gao , Weizhu Chen , Tuo Zhao

For multivariate data, dependence beyond pair-wise can be important. This is true, for example, in using functional MRI (fMRI) data to investigate brain functional connectivity. When one has more than a few variables, however, the number of…

Methodology · Statistics 2015-08-04 Steven P. Ellis , Arno Klein

A novel mathematical framework is proposed to describe the ecological and evolutionary consequences of consumer--resource interactions. Both the consumer and resource are assumed to consist of several (sub)species, which interact between…

Populations and Evolution · Quantitative Biology 2025-11-11 Alexander S. Bratus , Sergei V. Drozhzhin , Artem S. Novozhilov

It is well-known that biological and social interaction networks have a varying degree of redundancy, though a consensus of the precise cause of this is so far lacking. In this paper, we introduce a topological redundancy measure for…

In this paper we outline general considerations on parameter identifiability, and introduce the notion of weak local identifiability and gradient weak local identifiability. These are based on local properties of the likelihood, in…

Statistics Theory · Mathematics 2010-02-28 Mark P. Little , Wolfgang F. Heidenreich , Guangquan Li

We study consumption behaviour in systems with heterogeneous interacting agents. Two different models are introduced, respectively with long and short range interactions among agents. At any time step an agent decides whether or not to…

Statistical Mechanics · Physics 2008-12-02 Giulia Iori , Vassilis Koulovassilopoulos

The performance of an energy system under a real-time pricing mechanism depends on the consumption behavior of its customers, which involves uncertainties. In this paper, we consider a system operator that charges its customers with a…

Systems and Control · Computer Science 2016-11-17 Ceyhun Eksin , Hakan Delic , Alejandro Ribeiro

Currently, the biaffine classifier has been attracting attention as a method to introduce an attention mechanism into the modeling of binary relations. For instance, in the field of dependency parsing, the Deep Biaffine Parser by Dozat and…

Computation and Language · Computer Science 2018-10-22 Tomoki Matsuno , Katsuhiko Hayashi , Takahiro Ishihara , Hitoshi Manabe , Yuji Matsumoto
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