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Modern randomization methods in clinical trials are invariably adaptive, meaning that the assignment of the next subject to a treatment group uses the accumulated information in the trial. Some of the recent adaptive randomization methods…

Methodology · Statistics 2024-02-12 Alan R. Vazquez , Weng Kee Wong

This paper proposes estimation and inference procedures for the quantiles of individual heterogeneous slope coefficients within panel data. We develop a two-step quantile estimation framework for analyzing heterogeneity in individual…

Econometrics · Economics 2026-05-26 Antonio F. Galvao , Ulrich Hounyo , Jiahao Lin

Patients in clinical studies often exhibit heterogeneous treatment effect (HTE). Classical subgroup analyses provide inferential tools to test for effect modification, while modern machine learning methods estimate the Conditional Average…

Applications · Statistics 2026-01-05 Nan Miles Xi , Xin Huang , Lin Wang

For factor model, the involved covariance matrix often has no row sparse structure because the common factors may lead some variables to strongly associate with many others. Under the ultra-high dimensional paradigm, this feature causes…

Methodology · Statistics 2014-09-22 Junlong Zhao , Hongyu Zhao , Lixing Zhu

This paper introduces unit-specific heterogeneity in panel data threshold regression. We develop the asymptotic theory for models with heterogeneous thresholds, heterogeneous slope coefficients, and interactive fixed effects. The estimation…

Econometrics · Economics 2026-01-27 Marco Barassi , Yiannis Karavias , Chongxian Zhu

Statistical learning evolves quickly with more and more sophisticated models proposed to incorporate the complicated data structure from modern scientific and business problems. Varying index coefficient models extend varying coefficient…

Statistics Theory · Mathematics 2019-03-05 Li Jialiang , Lv Jing

Self-supervised pre-training, where large corpora of unlabeled data are used to learn representations for downstream fine-tuning, has become a cornerstone of modern machine learning. While a growing body of theoretical work has begun to…

Machine Learning · Computer Science 2026-03-31 Mohammad Tinati , Stephen Tu

Variable selection comprises an important step in many modern statistical inference procedures. In the regression setting, when estimators cannot shrink irrelevant signals to zero, covariates without relationships to the response often…

Statistics Theory · Mathematics 2025-03-28 Ka Long Keith Ho , Hien Duy Nguyen

A Bayesian multivariate model with a structured covariance matrix for multi-way nested data is proposed. This flexible modeling framework allows for positive and for negative associations among clustered observations, and generalizes the…

Methodology · Statistics 2024-08-27 Stef Baas , Richard J. Boucherie , Jean-Paul Fox

This paper focuses on the substantive application of multilevel LCA to the evolution of citizenship norms in a diverse array of democratic countries. To do so, we present a two-stage approach to fit multilevel latent class models: in the…

Methodology · Statistics 2023-07-21 Roberto Di Mari , Zsuzsa Bakk , Jennifer Oser , Jouni Kuha

This study introduces a general semiparametric clusterwise index distribution model to analyze how latent clusters affect the covariate-response relationships. By employing sufficient dimension reduction to account for the effects of…

Methodology · Statistics 2025-09-30 Jen-Chieh Teng , Chin-Tsang Chiang

Quantile regression is a powerful tool for detecting exposure-outcome associations given covariates across different parts of the outcome's distribution, but has two major limitations when the aim is to infer the effect of an exposure.…

This paper introduces a novel multi-stage decision-making model that integrates hypothesis testing and dynamic programming algorithms to address complex decision-making scenarios.Initially,we develop a sampling inspection scheme that…

Systems and Control · Electrical Eng. & Systems 2025-03-11 Ziyang Liu , Yurui Hu , Yihan Deng

A common goal in comparative effectiveness research is to estimate treatment effects on pre-specified subpopulations of patients. Though widely used in medical research, causal inference methods for such subgroup analysis remain…

Change-point models are widely used by statisticians to model drastic changes in the pattern of observed data. Least squares/maximum likelihood based estimation of change-points leads to curious asymptotic phenomena. When the change-point…

Statistics Theory · Mathematics 2015-10-20 Rui Song , Moulinath Banerjee , Michael R. Kosorok

Background: Subgroup analyses are frequently conducted in randomized clinical trials to assess evidence of heterogeneous treatment effect across patient subpopulations. Although randomization balances covariates within subgroups in…

Methodology · Statistics 2021-05-27 Siyun Yang , Fan Li , Laine E. Thomas , Fan Li

Varying coefficient model is often used in statistical modeling since it is more flexible than the parametric model. However, model detection and variable selection of varying coefficient model are poorly understood in mode regression.…

Methodology · Statistics 2020-09-23 Xuejun Ma , Yue Du , Jingli Wang

When estimating treatment effects with two-way fixed effects (2WFE) models, researchers often use matching as a pre-processing step when the parallel trends assumption is thought to hold conditionally on covariates. Specifically, in a first…

Econometrics · Economics 2026-02-17 Yihong Liu , Gonzalo Vazquez-Bare

In this paper, we study the problem of multiple change-point detection for a univariate sequence under the epidemic setting, where the behavior of the sequence alternates between a common normal state and different epidemic states. This is…

Methodology · Statistics 2021-01-07 Zifeng Zhao , Chun Yip Yau

In most nonrandomized observational studies, differences between treatment groups may arise not only due to the treatment but also because of the effect of confounders. Therefore, causal inference regarding the treatment effect is not as…

Methodology · Statistics 2018-07-04 Debashis Ghosh