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Panel data involving longitudinal measurements of the same set of participants taken over multiple time points is common in studies to understand childhood development and disease modeling. Deep hybrid models that marry the predictive power…

Machine Learning · Computer Science 2022-03-01 Jurijs Nazarovs , Rudrasis Chakraborty , Songwong Tasneeyapant , Sathya N. Ravi , Vikas Singh

Consider a subject or unit in a longitudinal biomedical, public health, engineering, economic, or social science study which is being monitored over a possibly random duration. Over time this unit experiences competing recurrent events and…

Methodology · Statistics 2024-12-30 Lili Tong , Piaomu Liu , Edsel Pena

This paper proposes an analysis methodology for the case where there is longitudinal data with destructive sampling of observational units, which come from experimental units that are measured at all times of the analysis. A mixed linear…

Methodology · Statistics 2024-11-26 C. A. Avellaneda , O. O. Melo , N. A. Cruz

In oncology clinical trials, tumor burden (TB) stands as a crucial longitudinal biomarker, reflecting the toll a tumor takes on a patient's prognosis. With certain treatments, the disease's natural progression shows the tumor burden…

Methodology · Statistics 2024-09-24 Ethan M. Alt , Yixiang Qu , Emily Damone , Jing-ou Liu , Chenguang Wang , Joseph G. Ibrahim

Commonly used methods to analyze incomplete longitudinal clinical trial data include complete case analysis (CC) and last observation carried forward (LOCF). However, such methods rest on strong assumptions, including missing completely at…

Statistics Theory · Mathematics 2007-06-13 Ivy Jansen , Caroline Beunckens , Geert Molenberghs , Geert Verbeke , Craig Mallinckrodt

In this survey we discuss the recent causal panel data literature. This recent literature has focused on credibly estimating causal effects of binary interventions in settings with longitudinal data, emphasizing practical advice for…

Econometrics · Economics 2024-06-26 Dmitry Arkhangelsky , Guido Imbens

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

Artificial Intelligence · Computer Science 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Data collected in clinical trials are often composed of multiple types of variables. For example, laboratory measurements and vital signs are longitudinal data of continuous or categorical variables, adverse events may be recurrent events,…

Methodology · Statistics 2023-01-12 Tuo Wang , Rachel Zilinskas , Ying Li , Yongming Qu

We carry out ANOVA comparisons of multiple treatments for longitudinal studies with missing values. The treatment effects are modeled semiparametrically via a partially linear regression which is flexible in quantifying the time effects of…

Statistics Theory · Mathematics 2012-11-14 Song Xi Chen , Ping-Shou Zhong

We are interested in survival analysis of hemodialysis patients for whom several biomarkers are recorded over time. Motivated by this challenging problem, we propose a general framework for multivariate joint longitudinal-survival modeling…

Electronic Health Records maintained in health care settings are a potential source of substantial clinical knowledge. The massive volume of data, unstructured nature of records and obligatory requirement of domain acquaintance together…

Information Retrieval · Computer Science 2015-10-13 Gargi Priyadarshini , Ashish Anand

In many longitudinal microarray studies, the gene expression levels in a random sample are observed repeatedly over time under two or more conditions. The resulting time courses are generally very short, high-dimensional, and may have…

Applications · Statistics 2013-02-26 Maurice Berk , Cheryl Hemingway , Michael Levin , Giovanni Montana

Intensive longitudinal biomarker data are increasingly common in scientific studies that seek temporally granular understanding of the role of behavioral and physiological factors in relation to outcomes of interest. Intensive longitudinal…

Methodology · Statistics 2024-01-17 Mingyan Yu , Zhenke Wu , Margaret Hicken , Michael R. Elliott

Joint modeling technique is a recent advancement in effectively analyzing the longitudinal history of patients with the occurrence of an event of interest attached to it. This procedure is successfully implemented in biomarker studies to…

Methodology · Statistics 2021-01-08 Gajendra K. Vishwakarma , Atanu Bhattacharjee , Souvik Banerjee

Electronic health record (EHR) data is sparse and irregular as it is recorded at irregular time intervals, and different clinical variables are measured at each observation point. In this work, we propose a multi-view features integration…

Machine Learning · Computer Science 2021-01-27 Yurim Lee , Eunji Jun , Heung-Il Suk

Older adults living with multiple chronic conditions (MCC) can considerably benefit from collecting and reflecting on their health data. Many older adults collect their health data using various approaches, such as digital tools or…

Human-Computer Interaction · Computer Science 2026-04-22 Shri Harini Ramesh , Foroozan Daneshzand , Matteo Sotelo , Mahsa Sinaei , Fateme Rajabiyazdi

Count data modeling has been extensively applied in medical sciences to analyze various healthcare datasets. Numerous probability models have been developed to address diverse aspects of healthcare data. In this study, we propose a novel…

Methodology · Statistics 2025-09-04 Peer Bilal Ahmad , Na Elah

Clinical data for ambulatory care, which accounts for 90% of the nations healthcare spending, is characterized by relatively small sample sizes of longitudinal data, unequal spacing between visits for each patient, with unequal numbers of…

Machine Learning · Computer Science 2018-12-03 Beau Norgeot , Dmytro Lituiev , Benjamin S. Glicksberg , Atul J. Butte

To address the multidimensional nature of health-related questions, advances in health research often require integrating information from various data sources within statistical analyses. When complementary information pertaining to the…

We consider analysis of dependent functional data that are correlated because of a longitudinal-based design: each subject is observed at repeated time visits and for each visit we record a functional variable. We propose a novel…

Methodology · Statistics 2015-06-30 So Young Park , Ana-Maria Staicu
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