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Class imbalance problems frequently occur in real-world tasks, and conventional deep learning algorithms are well known for performance degradation on imbalanced training datasets. To mitigate this problem, many approaches have aimed to…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Sumyeong Ahn , Jongwoo Ko , Se-Young Yun

Recently deep learning has been witnessing widespread adoption in various medical image applications. However, training complex deep neural nets requires large-scale datasets labeled with ground truth, which are often unavailable in many…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Wentao Zhu , Yeeleng S. Vang , Yufang Huang , Xiaohui Xie

Purpose: Lung nodule segmentation, i.e., the algorithmic delineation of the lung nodule surface, is a fundamental component of computational nodule analysis pipelines. We propose a new method for segmentation that is a machine learning…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Matthew C Hancock , Jerry F Magnan

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Chenglong Wang , Yun Liu , Fen Wang , Chengxiu Zhang , Yida Wang , Mei Yuan , Guang Yang

Pulmonary nodule detection using low-dose Computed Tomography (CT) is often the first step in lung disease screening and diagnosis. Recently, algorithms based on deep convolutional neural nets have shown great promise for automated nodule…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Hao Tang , Xingwei Liu , Xiaohui Xie

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Lung nodules suffer large variation in size and appearance in CT images. Nodules less than 10mm can easily lose information after down-sampling in convolutional neural networks, which results in low sensitivity. In this paper, a combination…

Computer Vision and Pattern Recognition · Computer Science 2018-08-02 Benyuan Sun , Zhen Zhou , Fandong Zhang , Xiuli Li , Yizhou Wang

Pulmonary nodule detection, false positive reduction and segmentation represent three of the most common tasks in the computeraided analysis of chest CT images. Methods have been proposed for eachtask with deep learning based methods…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Hao Tang , Chupeng Zhang , Xiaohui Xie

Lung cancer is a primary contributor to cancer-related mortality globally, highlighting the necessity for precise early detection of pulmonary nodules through low-dose CT (LDCT) imaging. Deep learning methods have improved nodule detection…

Quantitative Methods · Quantitative Biology 2025-12-10 Fateme Mobini , Mohammad Reza Hedyehzadeh , Mahdi Yousefi

Accurate detection of pulmonary nodules with high sensitivity and specificity is essential for automatic lung cancer diagnosis from CT scans. Although many deep learning-based algorithms make great progress for improving the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Jingya Liu , Liangliang Cao , Oguz Akin , Yingli Tian

This study evaluates whether integrating curriculum learning with diffusion-based synthetic augmentation can enhance the detection of difficult pulmonary nodules in chest radiographs, particularly those with low size, brightness, and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Pranav Sambhu , Om Guin , Madhav Sambhu , Jinho Cha

The superior performance of CNN on medical image analysis heavily depends on the annotation quality, such as the number of labeled image, the source of image, and the expert experience. The annotation requires great expertise and labour. To…

Image and Video Processing · Electrical Eng. & Systems 2021-04-06 Cheng Xue , Qiao Deng , Xiaomeng Li , Qi Dou , Pheng Ann Heng

The introduction of lung cancer screening programs will produce an unprecedented amount of chest CT scans in the near future, which radiologists will have to read in order to decide on a patient follow-up strategy. According to the current…

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kai Han , Chongwen Lyu , Lele Ma , Chengxuan Qian , Siqi Ma , Zheng Pang , Jun Chen , Zhe Liu

Lung cancer classification in screening computed tomography (CT) scans is one of the most crucial tasks for early detection of this disease. Many lives can be saved if we are able to accurately classify malignant/cancerous lung nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-09-20 Mundher Al-Shabi , Kelvin Shak , Maxine Tan

Though large-scale datasets are essential for training deep learning systems, it is expensive to scale up the collection of medical imaging datasets. Synthesizing the objects of interests, such as lung nodules, in medical images based on…

Computer Vision and Pattern Recognition · Computer Science 2019-01-01 Jie Yang , Siqi Liu , Sasa Grbic , Arnaud Arindra Adiyoso Setio , Zhoubing Xu , Eli Gibson , Guillaume Chabin , Bogdan Georgescu , Andrew F. Laine , Dorin Comaniciu

Detecting malignant pulmonary nodules at an early stage can allow medical interventions which may increase the survival rate of lung cancer patients. Using computer vision techniques to detect nodules can improve the sensitivity and the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Siqi Liu , Arnaud Arindra Adiyoso Setio , Florin C. Ghesu , Eli Gibson , Sasa Grbic , Bogdan Georgescu , Dorin Comaniciu

Lung nodule detection in chest CT is crucial for early lung cancer diagnosis, yet existing deep learning approaches face challenges when deployed in clinical settings with limited annotated data. While curriculum learning has shown promise…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Yi Luo , Yike Guo , Hamed Hooshangnejad , Kai Ding

In this work, we present a fully automated lung computed tomography (CT) cancer diagnosis system, DeepLung. DeepLung consists of two components, nodule detection (identifying the locations of candidate nodules) and classification…

Computer Vision and Pattern Recognition · Computer Science 2018-01-30 Wentao Zhu , Chaochun Liu , Wei Fan , Xiaohui Xie