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Recent advances in computational neuroscience demand models that balance biophysical realism with scalability. We present a hybrid neuron model combining the biophysical fidelity of Hodgkin-Huxley (HH) dynamics for taste receptor cells with…

Neurons and Cognition · Quantitative Biology 2025-10-02 Vladimir A. Lazovsky , Sergey V. Stasenko , Victor B. Kazantsev

Memristors have been suggested as neuromorphic computing elements. Spike-time dependent plasticity and the Hodgkin-Huxley model of the neuron have both been modelled effectively by memristor theory. The d.c. response of the memristor is a…

Emerging Technologies · Computer Science 2014-02-18 Deborah Gater , Attya Iqbal , Jeffrey Davey , Ella Gale

Neuronal models based on the Hodgkin-Huxley equation form a fundamental framework in the field of computational neuroscience. While the neuronal state is often modeled deterministically, experimental recordings show stochastic fluctuations,…

Neurons and Cognition · Quantitative Biology 2018-10-26 Pavol Bauer , Stefan Engblom , Sanja Mikulovic , Aleksandar Senek

Serotonergic, noradrenergic and dopaminergic brainstem (including midbrain) neurons, often exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz, though dopaminergic and noradrenergic neurons only exhibit such…

Neurons and Cognition · Quantitative Biology 2017-04-18 Henry C. Tuckwell , Ying Zhou , Nicholas J. Penington

Recent in vitro data show that neurons respond to input variance with varying sensitivities. Here, we demonstrate that Hodgkin-Huxley (HH) neurons can operate in two computational regimes, one that is more sensitive to input variance…

Neurons and Cognition · Quantitative Biology 2007-07-17 Brian Nils Lundstrom , Sungho Hong , Matthew H. Higgs , Adrienne L. Fairhall

Quantum computer technology harnesses the features of quantum physics for revolutionizing information processing and computing. As such, quantum computers use physical quantum gates that process information unitarily, even though the final…

We consider a stochastic Hodgkin-Huxley model driven by a periodic signal as model for the membrane potential of a pyramidal neuron. The associated five dimensional diffusion process is a time inhomogeneous highly degenerate diffusion for…

Probability · Mathematics 2012-07-03 Reinhard Höpfner , Eva Löcherbach , Michèle Thieullen

The stochastic opening and closing of voltage-gated ion channels produces noise in neurons. The effect of this noise on the neuronal performance has been modelled using either approximate or Langevin model, based on stochastic differential…

Neurons and Cognition · Quantitative Biology 2015-05-14 B. Sengupta , S. B. Laughlin , J. E. Niven

We address the question of optimality of entangled input states in quantum Gaussian memory channels. For a class of such channels, that can be traced back to the memoryless setting, we state a criterion which relate the optimality of…

Quantum Physics · Physics 2010-05-18 C. Lupo , S. Mancini

Spiking neural networks aim to emulate the brain's properties to achieve similar parallelism and high-processing power. A caveat of these neural networks is the high computational cost to emulate, while current proposals for analogue…

We study the frequency and phase synchronization in two coupled identical and nonidentical neurons with channel noise. The occupation number method is used to model the neurons in the context of stochastic Hodgkin-Huxley model in which the…

Neurons and Cognition · Quantitative Biology 2007-11-07 L. C. Yu , Yong Chen , Pan Zhang

Understanding the human brain is the biggest challenge for scientists in the twenty-first century. The Hodgkin-Huxley (HH) model is one of the most successful mathematical models for bio-realistic simulations of the brain. However, the…

Emerging Technologies · Computer Science 2020-04-29 Byungik Ahn

A quantum model of neural network is introduced and its phase structure is examined. The model is an extension of the classical Z(2) gauged neural network of learning and recalling to a quantum model by replacing the Z(2) variables, $S_i =…

Disordered Systems and Neural Networks · Physics 2007-05-23 Yukari Fujita , Tetsuo Matsui

Classical models for predicting current flow in excitable cells such as axons, originally proposed by Hodgkin and Huxley, rely on empirical voltage-gating parameters that quantify ion transport across sodium and potassium ion channels. We…

Biological Physics · Physics 2025-02-24 Vivaan Patel , Joshua D. Priosoetanto , Aashutosh Mistry , John Newman , Nitash P. Balsara

We applied a periodic magnetic field of frequency 16 Hz and amplitude 16 nT to a human I_Ks channel, expressed in a Xenopus oocyte and varied the membrane depolarization between -100 mV and +100 mV. We observed a maximal increase of about…

Quantitative Methods · Quantitative Biology 2009-05-21 M. Shaked , G. Gibor , B. Attali , Z. Schuss

Using the axiomatic definition of the coherence measure, such as the $l_{1}$ norm and the relative entropy, we study the phenomena of two-qubit system quantum coherence through quantum channels where successive uses of the channels are…

Quantum Physics · Physics 2016-12-30 You-neng Guo , Ke Zeng , Qing-long Tian , Zheng-da Li

The generation of spikes by neurons is energetically a costly process and the evaluation of the metabolic energy required to maintain the signalling activity of neurons a challenge of practical interest. Neuron models are frequently used to…

Chaotic Dynamics · Physics 2015-06-04 A. Moujahid , A. d'Anjou , F. J. Torrealdea

In order to create a novel model of memory and brain function, we focus our approach on the sub-molecular (electron), molecular (tubulin) and macromolecular (microtubule) components of the neural cytoskeleton. Due to their size and…

Quantum Physics · Physics 2007-05-23 A. Mershin , D. V. Nanopoulos , E. M. C. Skoulakis

Spiking Neural Networks have earned increased recognition in recent years owing to their biological plausibility and event-driven computation. Spiking neurons are the fundamental building components of Spiking Neural Networks. Those neurons…

Neural and Evolutionary Computing · Computer Science 2025-06-04 Amr Nabil , T. Nandha Kumar , Haider Abbas F. Almurib

Fifty years ago, Fitzugh introduced a phase portrait that became famous for a twofold reason: it captured in a physiological way the qualitative behavior of Hodgkin-Huxley model and it revealed the power of simple dynamical models to unfold…

Dynamical Systems · Mathematics 2011-12-13 Alessio Franci , Guillaume Drion , Vincent Seutin , Rodolphe Sepulchre