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Biclustering is a powerful unsupervised learning technique for simultaneously identifying coherent subsets of rows and columns in a data matrix, thus revealing local patterns that may not be apparent in global analyses. However, most…

Methodology · Statistics 2026-03-20 Sijian Fan , Ray Bai

In post genomic era with the advent of new technologies a huge amount of complex molecular data are generated with high throughput. The management of this biological data is definitely a challenging task due to complexity and heterogeneity…

Databases · Computer Science 2014-03-13 Ananya Bose , Suprativ Saha

A range of computational biology software (GROMACS, AMBER, NAMD, LAMMPS, OpenMM, Psi4 and RELION) was benchmarked on a representative selection of HPC hardware, including AMD EPYC 7742 CPU nodes, NVIDIA V100 and AMD MI250X GPU nodes, and an…

In this paper, we introduce a novel Generic distributEd clustEring frameworK (GEEK) beyond $k$-means clustering to process massive amounts of data. To deal with different data types, GEEK first converts data in the original feature space…

Databases · Computer Science 2021-06-22 Pingyi Luo , Qiang Huang , Anthony K. H. Tung

Similarity search is one of the most fundamental computations that are regularly performed on ever-increasing protein datasets. Scalability is of paramount importance for uncovering novel phenomena that occur at very large scales. We…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-06 Oguz Selvitopi , Saliya Ekanayake , Giulia Guidi , Muaaz G. Awan , Georgios A. Pavlopoulos , Ariful Azad , Nikos Kyrpides , Leonid Oliker , Katherine Yelick , Aydın Buluç

Binary code similarity detection (BCSD) is a fundamental technique for various application. Many BCSD solutions have been proposed recently, which mostly are embedding-based, but have shown limited accuracy and efficiency especially when…

Software Engineering · Computer Science 2024-03-01 Hao Wang , Zeyu Gao , Chao Zhang , Mingyang Sun , Yuchen Zhou , Han Qiu , Xi Xiao

The exponential growth of DNA sequencing data has outpaced traditional heuristic-based methods, which struggle to scale effectively. Efficient computational approaches are urgently needed to support large-scale similarity search, a…

Electroencephalography (EEG) plays a significant role in the Brain Computer Interface (BCI) domain, due to its non-invasive nature, low cost, and ease of use, making it a highly desirable option for widespread adoption by the general…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Giulio Tosato , Cesare M. Dalbagno , Francesco Fumagalli

Top-k selection, which identifies the largest or smallest k elements from a data set, is a fundamental operation in data-intensive domains such as databases and deep learning, so its scalability and efficiency are critical for these…

Data Structures and Algorithms · Computer Science 2025-01-28 Yifei Li , Bole Zhou , Jiejing Zhang , Xuechao Wei , Yinghan Li , Yingda Chen

Accurate intent classification is critical for efficient routing in customer service, ensuring customers are connected with the most suitable agents while reducing handling times and operational costs. However, as companies expand their…

Computation and Language · Computer Science 2025-11-18 Ziji Zhang , Michael Yang , Zhiyu Chen , Yingying Zhuang , Shu-Ting Pi , Qun Liu , Rajashekar Maragoud , Vy Nguyen , Anurag Beniwal

Modern HPC file systems can contain billions of files and hundreds of petabytes of data, making even simple questions increasingly intractable to answer. Traditional file system utilities such as find and du fail to scale to these sizes.…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-14 Haochen Pan , Ryan Chard , Song Young Oh , Maxime Gonthier , Valérie Hayot-Sasson , Geoffrey Lentner , Joe Bottigliero , Rachana Ananthakrishnan , Kyle Chard , Ian Foster

High-density DNA arrays, used to monitor gene expression at a genomic scale, have produced vast amounts of information which require the development of efficient computational methods to analyze them. The important first step is to extract…

Biological Physics · Physics 2009-10-31 G. Getz , E. Levine , E. Domany , M. Q. Zhang

We introduce the Granite Embedding models, a family of encoder-based embedding models designed for retrieval tasks, spanning dense-retrieval and sparse retrieval architectures, with both English and Multilingual capabilities. This report…

Brain-computer interface (BCI) provides an alternative means to communicate and it has sparked growing interest in the past two decades. Specifically, for Steady-State Visual Evoked Potential based BCI, marked improvement has been made in…

Signal Processing · Electrical Eng. & Systems 2020-06-24 Bingchuan Liu , Xiaoshan Huang , Yijun Wang , Xiaogang Chen , Xiaorong Gao

HEP-Frame is a new C++ package designed to efficiently perform analyses of data sets from a very large number of events, like those available at the Large Hadron Collider (LHC) at CERN, Geneva. It mainly targets high performance servers and…

High Energy Physics - Experiment · Physics 2023-03-10 A. Pereira , A. Onofre , A. Proenca

Evolutionary multi-objective clustering (EMOC), a modern clustering technique, has been widely applied to extract patterns, allowing us to analyze different aspects of complex data by considering multiple criteria. In this article, we…

Machine Learning · Computer Science 2022-04-04 Cristina Y. Morimoto , Aurora Pozo , Marcílio C. P. de Souto

Objective. This study conduct an extensive Brain-computer interfaces (BCI) reproducibility analysis on open electroencephalography datasets, aiming to assess existing solutions and establish open and reproducible benchmarks for effective…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Sylvain Chevallier , Igor Carrara , Bruno Aristimunha , Pierre Guetschel , Sara Sedlar , Bruna Lopes , Sebastien Velut , Salim Khazem , Thomas Moreau

Identifying a biclique with the maximum number of edges bears considerable implications for numerous fields of application, such as detecting anomalies in E-commerce transactions, discerning protein-protein interactions in biology, and…

Quantum Physics · Physics 2023-09-12 Xiaofan Li , Prasenjit Mitra , Rui Zhou , Wolfgang Nejdl

This paper proposes Genetic Algorithm with Border Trades (GAB), a novel modification of the standard genetic algorithm that enhances exploration by incorporating new chromosome patterns in the breeding process. This approach significantly…

Machine Learning · Computer Science 2025-06-27 Qingchuan Lyu

Chromatin conformation capture technologies such as Hi-C have revealed that the genome is organized in a hierarchy of structures spanning multiple scales observed at different resolutions. Current algorithms often focus on specific…

Genomics · Quantitative Biology 2025-12-22 Vipin Kumar , Roberto Rossini , Jonas Paulsen , Anthony Mathelier