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Disease progression models infer group-level temporal trajectories of change in patients' features as a chronic degenerative condition plays out. They provide unique insight into disease biology and staging systems with individual-level…

Machine Learning · Computer Science 2025-06-25 Peter A. Wijeratne , Daniel C. Alexander

Fault intensity diagnosis (FID) plays a pivotal role in monitoring and maintaining mechanical devices within complex industrial systems. As current FID methods are based on chain of thought without considering dependencies among target…

Hierarchical factor models, which include the bifactor model as a special case, are useful in social and behavioural sciences for measuring hierarchically structured constructs. Specifying a hierarchical factor model involves imposing…

Methodology · Statistics 2026-01-06 Jiawei Qiao , Yunxiao Chen , Zhiliang Ying

This work presents a new model and estimation procedure for the illness-death survival data where the hazard functions follow accelerated failure time (AFT) models. A shared frailty variate induces positive dependence among failure times of…

Methodology · Statistics 2022-05-10 Lea Kats , Malka Gorfine

In this paper, we introduce a novel high-dimensional Factor-Adjusted sparse Partially Linear regression Model (FAPLM), to integrate the linear effects of high-dimensional latent factors with the nonparametric effects of low-dimensional…

Methodology · Statistics 2025-01-14 Yanmei Shi , Meiling Hao , Yanlin Tang , Xu Guo

We aim to create a framework for transfer learning using latent factor models to learn the dependence structure between a larger source dataset and a target dataset. The methodology is motivated by our goal of building a risk-assessment…

Machine Learning · Statistics 2016-12-05 Elizabeth C Lorenzi , Zhifei Sun , Erich Huang , Ricardo Henao , Katherine A Heller

Most prediction models that are used in medical research fail to accurately predict health outcomes due to methodological limitations. Using routinely collected patient data, we explore the use of a Cox proportional hazard (PH) model within…

Methodology · Statistics 2019-07-19 John Mbotwa , Marc de Kamps , Paul D. Baxter , Mark S. Gilthorpe

The current high-dimensional linear factor models fail to account for the different types of variables, while high-dimensional nonlinear factor models often overlook the overdispersion present in mixed-type data. However, overdispersion is…

Methodology · Statistics 2024-08-22 Jinyu Nie , Zhilong Qin , Wei Liu

Latent factor models that integrate data from multiple sources/studies or modalities have garnered considerable attention across various disciplines. However, existing methods predominantly focus either on multi-study integration or…

Methodology · Statistics 2025-07-15 Wei Liu , Qingzhi Zhong

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

Machine Learning · Computer Science 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu

We propose a dynamic multiplicative factor model for process data, which arise from complex problem-solving items, an emerging testing mode in large-scale educational assessment. The proposed model can be viewed as an extension of the…

Methodology · Statistics 2026-02-26 Fangyi Chen , Hok Kan Ling , Zhiliang Ying

In industrial big data scenarios, high-dimensional sparse matrices (HDI) are widely used to characterize high-order interaction relationships among massive nodes. The stochastic gradient descent-based latent factor analysis (SGD-LFA) method…

Machine Learning · Computer Science 2025-08-26 Jinli Li , Shiyu Long , Minglian Han

In this study, we develop a latent factor model for analysing high-dimensional binary data. Specifically, a standard probit model is used to describe the regression relationship between the observed binary data and the continuous latent…

Methodology · Statistics 2024-04-15 Jiaxin Shi , Yuan Gao , Rui Pan , Hansheng Wang

To enhance the precision of cancer prognosis, recent research has increasingly focused on multimodal survival methods by integrating genomic data and histology images. However, current approaches overlook the fact that the proteome serves…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Junjie Zhou , Bao Xue , Meiling Wang , Wei Shao , Daoqiang Zhang

We present neural frailty machine (NFM), a powerful and flexible neural modeling framework for survival regressions. The NFM framework utilizes the classical idea of multiplicative frailty in survival analysis to capture unobserved…

Machine Learning · Computer Science 2023-10-05 Ruofan Wu , Jiawei Qiao , Mingzhe Wu , Wen Yu , Ming Zheng , Tengfei Liu , Tianyi Zhang , Weiqiang Wang

The management of chronic Heart Failure (HF) presents significant challenges in modern healthcare, requiring continuous monitoring, early detection of exacerbations, and personalized treatment strategies. In this paper, we present a…

In the context of clinical and biomedical studies, joint frailty models have been developed to study the joint temporal evolution of recurrent and terminal events, capturing both the heterogeneous susceptibility to experiencing a new…

Methodology · Statistics 2023-11-08 Chiara Masci , Marta Spreafico , Francesca Ieva

We introduce a HD DCC-HEAVY class of hierarchical-type factor models for high-dimensional covariance matrices, employing the realized measures built from higher-frequency data. The modelling approach features straightforward estimation and…

Econometrics · Economics 2024-07-17 Emilija Dzuverovic , Matteo Barigozzi

We present a new probabilistic model to address semi-nonnegative matrix factorization (SNMF), called Skellam-SNMF. It is a hierarchical generative model consisting of prior components, Skellam-distributed hidden variables and observed data.…

Machine Learning · Computer Science 2021-07-08 Benoit Fuentes , Gaël Richard

Black box variational inference allows researchers to easily prototype and evaluate an array of models. Recent advances allow such algorithms to scale to high dimensions. However, a central question remains: How to specify an expressive…

Machine Learning · Statistics 2016-06-01 Rajesh Ranganath , Dustin Tran , David M. Blei