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The purpose of this work is to provide a fast and accurate scatter artifacts correction algorithm for cone beam CT (CBCT) imaging. The method starts with an estimation of coarse scatter profiles for a set of CBCT data in either image domain…

The Computed Tomography (CT) for diagnosis of lesions in human internal organs is one of the most fundamental topics in medical imaging. Low-dose CT, which offers reduced radiation exposure, is preferred over standard-dose CT, and therefore…

X-ray images play a vital role in the intraoperative processes due to their high resolution and fast imaging speed and greatly promote the subsequent segmentation, registration and reconstruction. However, over-dosed X-rays superimpose…

X-ray imaging is a prevalent technique for non-invasively visualizing the interior of the human body and opaque instruments. In most commercial x-ray modalities, an image is formed by measuring the x-rays that pass through the object of…

Computer vision tasks require processing large amounts of data to perform image classification, segmentation, and feature extraction. Optical preprocessors can potentially reduce the number of floating point operations required by computer…

Objective Positron emission tomography (PET) allows imaging of patho-physiological information as a form of rate constants from a dynamic image. The rate constant image(s) may be affected from noise on the dynamic image. We introduced an…

X-ray computed tomography (CT) is widely utilized in the medical, industrial, and other fields to nondestructively generate three-dimensional structural images of objects. However, CT images are often affected by various artifacts, with…

One of the major challenges in design and developing of PET, scanners are the presence of inactive areas between the detector blocks which degrade the image spatial resolution and leads to streaking artifacts especially when we employ…

Computed tomography (CT) has become an essential part of modern science and medicine. A CT scanner consists of an X-ray source that is spun around an object of interest. On the opposite end of the X-ray source, a detector captures X-rays…

With the increasing popularity of PET-MR scanners in clinical applications, synthesis of CT images from MR has been an important research topic. Accurate PET image reconstruction requires attenuation correction, which is based on the…

Combined use of PET and dual-energy CT provides complementary information for multi-parametric imaging. PETenabled dual-energy CT combines a low-energy x-ray CT image with a high-energy &\gamma&-ray CT (GCT) image reconstructed from…

Purpose: This study proposes a systematic method for determining the optimal x-ray tube settings/energy windows and fluence for minimal noise and maximum CNR in material density images obtained from DECT scans by fixing the subject size and…

Computed tomography (CT) to cone-beam computed tomography (CBCT) deformable image registration (DIR) is a crucial step in adaptive radiation therapy. Current intensity-based registration algorithms, such as demons, may fail in the context…

Many clinical applications depend critically on the accurate differentiation and classification of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and…

In this paper, we first propose a variational model for the limited-angle computed tomography (CT) image reconstruction and then convert the model into an end-to-end deep network.We use the penalty method to solve the model and divide it…

In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is, therefore, challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable…

Multispectral computed tomography (CT) enables advanced material characterization by acquiring energy-resolved projection data. However, since the incoming X-ray flux is be distributed across multiple narrow energy bins, the photon count…

Defective and inconsistent responses in CT detectors can cause ring and streak artifacts in the reconstructed images, making them unusable for clinical purposes. In recent years, several ring artifact reduction solutions have been proposed…

Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR…

The low-density imaging performance of a zone plate based nano-resolution hard X-ray computed tomography (CT) system can be significantly improved by incorporating a grating-based Lau interferometer. Due to the diffraction, however, the…