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The role of pulmonary surfactant is to reduce the surface tension in the lungs and to facilitate breathing. Surfactant replacement therapy (SRT) aims at bringing a substitute by instillation into the airways, a technique that has proven to…

Soft Condensed Matter · Physics 2021-09-21 L. P. A. Thai , F. Mousseau , E. K. Oikonomou , J. -F. Berret

Biological cells utilize membranes and liquid-like droplets, known as biomolecular condensates, to structure their interior. The interaction of droplets and membranes, despite being involved in several key biological processes, is so far…

Soft Condensed Matter · Physics 2024-02-21 Marcel Mokbel , Dominic Mokbel , Susanne Liese , Christoph A. Weber , Sebastian Aland

For most finite element simulations, boundary-conforming meshes have significant advantages in terms of accuracy or efficiency. This is particularly true for complex domains. However, with increased complexity of the domain, generating a…

Numerical Analysis · Mathematics 2021-04-07 Jan Helmig , Fabian Key , Marek Behr , Stefanie Elgeti

We develop a robust cut finite element method for a model of diffusion in fractured media consisting of a bulk domain with embedded cracks. The crack has its own pressure field and can cut through the bulk mesh in a very general fashion.…

Numerical Analysis · Mathematics 2020-06-03 Erik Burman , Peter Hansbo , Mats G. Larson

In this work, we investigate flow topology modifications produced by a swarm of large surfactant-laden droplets released in a turbulent channel flow. Droplets have same density and viscosity of the carrier fluid, so that only surface…

Fluid Dynamics · Physics 2023-09-26 Giovanni Soligo , Alessio Roccon , Alfredo Soldati

We study a finite element approximation of a coupled fluid-structure interaction consisting of a three-dimensional incompressible viscous fluid governed by the unsteady Stokes equations and a two-dimensional elastic plate. To avoid the use…

Numerical Analysis · Mathematics 2026-02-10 Lander Besabe , Hyesuk Lee

A Galerkin finite element method for the membrane elasticity problem on a meshed surface is constructed by using two-dimensional elements extended into three dimensions. The membrane finite element model is established using the intrinsic…

Numerical Analysis · Mathematics 2012-03-16 Peter Hansbo , Mats G. Larson

This work introduces a scaffolding framework to compactly parametrise solid structures with conforming NURBS elements for isogeometric analysis. A novel formulation introduces a topological, geometrical and parametric subdivision of the…

Computational Geometry · Computer Science 2022-06-10 Stefano Moriconi , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

We propose a novel cut finite element method for the numerical solution of the Biot system of poroelasticity. The Biot system couples elastic deformation of a porous solid with viscous fluid flow and commonly arises on domains with complex…

Numerical Analysis · Mathematics 2026-02-10 Nanna Berre , Kent-Andre Mardal , André Massing , Ivan Yotov

A microfluidic device is constructed from PDMS with a single channel having a short section that is a thin flexible membrane, in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a…

Soft Condensed Matter · Physics 2020-07-03 Debadi Chakraborty , J. Ravi Prakash , Leslie Yeo , James Friend

This paper studies a model of two-phase flow with an immersed material viscous interface and a finite element method for numerical solution of the resulting system of PDEs. The interaction between the bulk and surface media is characterized…

Numerical Analysis · Mathematics 2021-06-08 Maxim Olshanskii , Annalisa Quaini , Qi Sun

In this paper we study the dynamics of a layer of incompressible viscous fluid bounded below by a rigid boundary and above by a free boundary, in the presence of a uniform gravitational field. We assume that a mass of surfactant is present…

Analysis of PDEs · Mathematics 2017-02-09 Ian Tice , Lei Wu

This work presents a novel numerical investigation of the dynamics of free-boundary flows of viscoelastic liquid membranes. The governing equation describes the balance of linear momentum, in which the stresses include the viscoelastic…

Fluid Dynamics · Physics 2022-04-12 Valeria Barra , Shawn A. Chester , Shahriar Afkhami

A mechanical model and numerical method for structural membranes implied by all isosurfaces of a level-set function in a three-dimensional bulk domain are proposed. The mechanical model covers large displacements in the context of the…

Computational Engineering, Finance, and Science · Computer Science 2023-08-02 Thomas-Peter Fries , Michael W. Kaiser

A model for the limiting surface tension of surfactant solutions (surface tension at and above the critical micelle concentration, cmc) was developed. This model takes advantage of the equilibrium between the surfactant molecules on the…

Many lipid membrane-mediated transport processes--such as mechanically-gated channel activation and solute transport--involve structural and dynamical features on membrane thickness length scales. Most existing membrane models, however,…

Soft Condensed Matter · Physics 2025-08-29 Zachary G. Lipel , Yannick A. D. Omar , Dimitrios Fraggedakis

Using numerical simulations, we investigate the effects of Marangoni stresses induced by surfactants on the effective slip length of liquid-infused surfaces (LIS) with transverse grooves. The surfactants are assumed soluble in the external…

Fluid Dynamics · Physics 2022-11-09 Johan Sundin , Shervin Bagheri

Computational modelling offers a cost-effective and time-efficient alternative to experimental studies in biomedical engineering. In cardiac electro-mechanics, finite element method (FEM)-based simulations provide valuable insights into…

Computational Engineering, Finance, and Science · Computer Science 2025-08-20 Tan Tran , Denisa Martonova , Sigrid Leyendecker

A unified fluid-structure interaction (FSI) formulation is presented for solid, liquid and mixed membranes. Nonlinear finite elements (FE) and the generalized-alpha scheme are used for the spatial and temporal discretization. The membrane…

Computational Physics · Physics 2018-12-31 Roger A. Sauer , Tobias Luginsland

We develop a finite element method for a large deformation membrane elasticity problem on meshed surfaces using a tangential differential calculus approach that avoids the use of classical differential geometric methods. The method is also…

Numerical Analysis · Mathematics 2014-10-30 Peter Hansbo , Mats G. Larson , Fredrik Larsson