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In video-assisted thoracoscopic surgeries, successful procedures of nodule resection are highly dependent on the precise estimation of lung deformation between the inflated lung in the computed tomography (CT) images during preoperative…

Computer Vision and Pattern Recognition · Computer Science 2021-08-20 Utako Yamamoto , Megumi Nakao , Masayuki Ohzeki , Junko Tokuno , Toyofumi Fengshi Chen-Yoshikawa , Tetsuya Matsuda

Diffeomorphic deformable image registration is crucial in many medical image studies, as it offers unique, special properties including topology preservation and invertibility of the transformation. Recent deep learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Tony C. W. Mok , Albert C. S. Chung

Explainability of deep neural networks is one of the most challenging and interesting problems in the field. In this study, we investigate the topic focusing on the interpretability of deep learning-based registration methods. In…

The majority of current research in deep learning based image registration addresses inter-patient brain registration with moderate deformation magnitudes. The recent Learn2Reg medical registration benchmark has demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Mattias P. Heinrich , Lasse Hansen

Purpose: In surgical navigation, pre-operative organ models are presented to surgeons during the intervention to help them in efficiently finding their target. In the case of soft tissue, these models need to be deformed and adapted to the…

Graphics · Computer Science 2019-04-02 Micha Pfeiffer , Carina Riediger , Jürgen Weitz , Stefanie Speidel

Image registration is a key technique in medical image analysis to estimate deformations between image pairs. A good deformation model is important for high-quality estimates. However, most existing approaches use ad-hoc deformation models…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Marc Niethammer , Roland Kwitt , Francois-Xavier Vialard

Cone-beam CT (CBCT)-based online adaptive radiotherapy calls for accurate auto-segmentation to reduce the time cost for physicians to edit contours. However, deep learning (DL)-based direct segmentation of CBCT images is a challenging task,…

Medical Physics · Physics 2023-02-22 Xiao Liang , Howard Morgan , Ti Bai , Michael Dohopolski , Dan Nguyen , Steve Jiang

Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) enables us to probe the microstructural arrangement of cardiomyocytes within the myocardium in vivo and non-invasively, which no other imaging modality allows. This innovative technology…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Michael Tanzer , Pedro Ferreira , Andrew Scott , Zohya Khalique , Maria Dwornik , Dudley Pennell , Guang Yang , Daniel Rueckert , Sonia Nielles-Vallespin

Purpose: To validate the accuracy of 4D Monte Carlo (4DMC) simulations to calculate dose deliveries to a deforming anatomy in the presence of realistic respiratory motion traces. A previously developed deformable lung phantom comprising an…

Medical Physics · Physics 2023-05-04 Sara Gholampourkashi , Joanna E. Cygler , Bernie Lavigne , Emily Heath

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

In laparoscopic liver surgery, augmented reality technology enhances intraoperative anatomical guidance by overlaying 3D liver models from preoperative CT/MRI onto laparoscopic 2D views. However, existing registration methods lack explicit…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ruize Cui , Jialun Pei , Haiqiao Wang , Jun Zhou , Jeremy Yuen-Chun Teoh , Pheng-Ann Heng , Jing Qin

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

MRI-guided radiation therapy (MRgRT) offers a precise and adaptive approach to treatment planning. Deep learning applications which augment the capabilities of MRgRT are systematically reviewed. MRI-guided radiation therapy offers a…

Medical Physics · Physics 2023-03-31 Zach Eidex , Yifu Ding , Jing Wang , Elham Abouei , Richard L. J. Qiu , Tian Liu , Tonghe Wang , Xiaofeng Yang

3D ultrasound (3DUS) becomes more interesting for target tracking in radiation therapy due to its capability to provide volumetric images in real-time without using ionizing radiation. It is potentially usable for tracking without using…

Image and Video Processing · Electrical Eng. & Systems 2022-01-11 Daniel Wulff , Jannis Hagenah , Floris Ernst

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

Diffeomorphic deformable image registration ensures smooth invertible transformations across inspiratory and expiratory chest CT scans. Yet, in practice, deep learning-based diffeomorphic methods struggle to capture large deformations…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Muhammad F. A. Chaudhary , Stephanie M. Aguilera , Arie Nakhmani , Joseph M. Reinhardt , Surya P. Bhatt , Sandeep Bodduluri

We propose a supervised nonrigid image registration method, trained using artificial displacement vector fields (DVF), for which we propose and compare three network architectures. The artificial DVFs allow training in a fully supervised…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Hessam Sokooti , Bob de Vos , Floris Berendsen , Mohsen Ghafoorian , Sahar Yousefi , Boudewijn P. F. Lelieveldt , Ivana Isgum , Marius Staring

Applications in fields ranging from home care to warehouse fulfillment to surgical assistance require robots to reliably manipulate the shape of 3D deformable objects. Analytic models of elastic, 3D deformable objects require numerous…

Robotics · Computer Science 2024-02-20 Bao Thach , Brian Y. Cho , Shing-Hei Ho , Tucker Hermans , Alan Kuntz

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

Medical Physics · Physics 2025-07-22 Xia Li , Runzhao Yang , Muheng Li , Xiangtai Li , Antony J. Lomax , Joachim M. Buhmann , Ye Zhang

Lung cancer is the leading cause of cancer-related death worldwide, and early diagnosis is critical to improving patient outcomes. To diagnose cancer, a highly trained pulmonologist must navigate a flexible bronchoscope deep into the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-19 Jake Sganga , David Eng , Chauncey Graetzel , David B. Camarillo
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