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Magnetic Resonance Imaging (MRI) can characterize and discriminate among tissues using their diverse physical and biochemical properties. Unfortunately, submicrometer screening of biological specimens is presently not possible, mainly due…

Mesoscale and Nanoscale Physics · Physics 2010-11-03 C. A. Meriles , L. Jiang , G. Goldstein , J. S. Hodges , J. R. Maze , M. D. Lukin , P. Cappellaro

Magnetic resonance spectroscopy is universally regarded as one of the most important tools in chemical and bio-medical research. However, sensitivity limitations typically restrict imaging resolution to length scales greater than 10 \mu m.…

Nuclear magnetic resonance (NMR) is a powerful method for determining the structure of molecules and proteins. While conventional NMR requires averaging over large ensembles, recent progress with single-spin quantum sensors has created the…

Nitrogen vacancy (NV) color centers in diamond are a leading modality for both superresolution optical imaging and nanoscale magnetic field sensing. In this work, we solve the remaining key challenge of performing optical magnetic imaging…

Nuclear spin imaging at the atomic level is essential for the understanding of fundamental biological phenomena and for applications such as drug discovery. The advent of novel nano-scale sensors has given hope of achieving the…

Quantum Physics · Physics 2015-11-25 Ashok Ajoy , Ulf Bissbort , Mikhail D. Lukin , Ronald L. Walsworth , Paola Cappellaro

Quantum sensors based on solid-state spins provide tremendous opportunities in a wide range of fields from basic physics and chemistry to biomedical imaging. However, integrating them into a scanning probe microscope to enable practical,…

Mesoscale and Nanoscale Physics · Physics 2016-01-19 Jean-Philippe Tetienne , Alain Lombard , David A. Simpson , Cameron Ritchie , Jianing Lu , Paul Mulvaney , Lloyd C. L. Hollenberg

Magnetic resonance imaging, based on the manipulation and detection of nuclear spins, is a powerful imaging technique that typically operates on the scale of millimeters to microns. Using magnetic resonance force microscopy, we have…

Other Condensed Matter · Physics 2007-06-27 H. J. Mamin , M. Poggio , C. L. Degen , D. Rugar

Measuring spins is the corner stone of a variety of analytical techniques including modern magnetic resonance imaging (MRI). The full potential of spin imaging and sensing across length scales is hindered by the achievable signal-to-noise…

Mesoscale and Nanoscale Physics · Physics 2015-06-12 S. Steinert , F. Ziem , L. Hall , A. Zappe , M. Schweikert , A. Aird , G. Balasubramanian , L. Hollenberg , J. Wrachtrup

The detection of ensembles of spins under ambient conditions has revolutionized the biological, chemical, and physical sciences through magnetic resonance imaging and nuclear magnetic resonance. Pushing sensing capabilities to the…

Mesoscale and Nanoscale Physics · Physics 2013-04-05 M. S. Grinolds , S. Hong , P. Maletinsky , L. Luan , M. D. Lukin , R. L. Walsworth , A. Yacoby

We demonstrate a wide-band all-optical method of nanoscale magnetic resonance (MR) spectroscopy under ambient conditions. Our method relies on cross-relaxation between a probe spin, the electronic spin of a nitrogen-vacancy centre in…

Nuclear magnetic resonance spectroscopy with solid-state spin sensors is a promising pathway for the detection of nuclear spins at the micro- and nanoscale. Although many nanoscale experiments rely on a single sensor spin for the detection…

We present a technique that uses an ensemble of nitrogen-vacancy (NV) centers in diamond to image magnetic fields with high spatio-temporal resolution and sensitivity. A focused laser beam is raster-scanned using an acousto-optic deflector…

Optically-detected magnetic resonance using Nitrogen Vacancy (NV) color centres in diamond is a leading modality for nanoscale magnetic field imaging, as it provides single electron spin sensitivity, three-dimensional resolution better than…

Mesoscale and Nanoscale Physics · Physics 2015-10-28 K. Arai , C. Belthangady , H. Zhang , N. Bar-Gill , S. J. DeVience , P. Cappellaro , A. Yacoby , R. L. Walsworth

Nuclear magnetic resonance imaging (MRI) at the atomic scale offers exciting prospects for determining the structure and function of individual molecules and proteins. Quantum defects in diamond have recently emerged as a promising platform…

Quantum Physics · Physics 2022-04-06 K. S. Cujia , K. Herb , J. Zopes , J. M. Abendroth , C. L. Degen

The implementation of nuclear magnetic resonance (NMR) at the nanoscale is a major challenge, as conventional systems require relatively large ensembles of spins and limit resolution to mesoscopic scales. New approaches based on quantum…

Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are well-established techniques that provide valuable information in a diverse set of disciplines but are currently limited to macroscopic sample volumes. Here we…

Detecting nuclear spins using single Nitrogen-Vacancy (NV) centers is of particular importance in nano-scale science and engineering, but often suffers from the heating effect of microwave fields for spin manipulation, especially under high…

Quantum Physics · Physics 2024-09-06 Zhiyi Hu , Fengjian Jiang , Jingyan He , Yulin Dai , Ya Wang , Nanyang Xu , Jiangfeng Du

Two-dimensional Nuclear Magnetic Resonance (NMR) is essential in molecular structure determination. The Nitrogen-Vacancy (NV) center in diamond has been proposed and developed as an outstanding quantum sensor to realize NMR in nanoscale. In…

The application of magnetic resonance (MR) spectroscopy at progressively smaller length scales may eventually permit "chemical imaging" of spins at the surfaces of materials and biological complexes. In particular, the negatively charged…

Mesoscale and Nanoscale Physics · Physics 2015-06-18 Hai-Jing Wang , Chang S. Shin , Scott J. Seltzer , Claudia E. Avalos , Alexander Pines , Vikram S. Bajaj

We perform sensitive nuclear magnetic resonance (NMR) with spin ensembles which are polarized by nitrogen vacancy centers (NV centers) in diamond at room-temperature. With a near shot-noise-limited photoluminescence detection and a highly…

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