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Living systems operate far from equilibrium, yet few general frameworks provide global bounds on biological transients. In high-dimensional biological networks like ecosystems, long transients arise from the separate timescales of…

Biological Physics · Physics 2025-04-15 William Gilpin

The spatial character of territorial systems plays a crucial role in the emergence of their complexities. This contribution aims at illustrating to what extent different types of complexities can be exhibited in models of such systems. We…

Physics and Society · Physics 2019-01-29 Juste Raimbault

A broad class of systems, including ecological, epidemiological, and sociological ones, are characterized by populations of individuals assigned to specific categories, e.g., a chemical species, an opinion or an epidemic state, that are…

Statistical Mechanics · Physics 2025-07-17 Giorgio Vittorio Visco , Johannes Nauta , Tomas Scagliarini , Oriol Artime , Manlio De Domenico

Effective control requires knowledge of the process dynamics to guide the system toward desired states. In many control applications this knowledge is expressed mathematically or through data-driven models, however, as complexity grows…

Systems and Control · Electrical Eng. & Systems 2024-05-24 Joseph Park , George Sugihara , Gerald Pao

Systems engineering approaches use high-level models to capture the architecture and behavior of the system. However, when safety engineers conduct safety and reliability analysis, they have to create formal models, such as fault-trees,…

Software Engineering · Computer Science 2020-04-29 Simon József Nagy , Bence Graics , Kristóf Marussy , András Vörös

Molecular dynamics simulations provide theoretical insight into the microscopic behavior of materials in condensed phase and, as a predictive tool, enable computational design of new compounds. However, because of the large temporal and…

Chemical Physics · Physics 2020-06-18 Wujie Wang , Rafael Gómez-Bombarelli

Recent work in the field of multi-agent systems has sought to use techniques and concepts from the field of formal methods to provide rigorous theoretical analysis and guarantees on complex systems where multiple agents strategically…

Computer Science and Game Theory · Computer Science 2026-04-28 Senthil Rajasekaran , Moshe Y. Vardi

Improving the effectiveness of problem solving in teams is an important research topic due to the complexity and cross-disciplinary nature of modern problems. It is unlikely that an individual can successfully tackle alone such problems.…

Human-Computer Interaction · Computer Science 2023-08-15 Alex Doboli , Ryan Duke

Biological systems, unlike physical or chemical systems, are characterized by the very inhomogeneous distribution of their components. The immune system, in particular, is notable for self-organizing its structure. Classically, the dynamics…

Statistical Mechanics · Physics 2007-05-23 Yoram Louzoun , Sorin Solomon , Henri Atlan , Irun R. Cohen

A variety of computational models have been developed to describe active matter at different length and time scales. The diversity of the methods and the challenges in modeling active matter---ranging from molecular motors and cytoskeletal…

Soft Condensed Matter · Physics 2020-04-21 M Reza Shaebani , Adam Wysocki , Roland G Winkler , Gerhard Gompper , Heiko Rieger

Mathematical models play an increasingly important role in the interpretation of biological experiments. Studies often present a model that generates the observations, connecting hypothesized process to an observed pattern. Such generative…

Populations and Evolution · Quantitative Biology 2014-06-18 Steven A. Frank

We study special systems with infinitely many degrees of freedom with regard to dynamical evolution and fulfillment of constraint conditions. Attention is focused on establishing a meaningful functional framework, and for that purpose,…

Quantum Physics · Physics 2007-05-23 John R. Klauder

Contemporary tasks of complex system simulation are often related to the issue of uncertainty management. It comes from the lack of information or knowledge about the simulated system as well as from restrictions of the model set being…

The mathematical formalisms used to model biological systems induce both latent and ambiguous assumptions that can limit or distort their representational capabilities. Developing formalisms that can represent systems more precisely is…

Quantitative Methods · Quantitative Biology 2026-05-25 Léo Diaz , Sean T. Vittadello , Michael P. H. Stumpf

Biological systems, from a cell to the human brain, are inherently complex. A powerful representation of such systems, described by an intricate web of relationships across multiple scales, is provided by complex networks. Recently, several…

Quantitative Methods · Quantitative Biology 2018-02-06 M. De Domenico

Urban evolution processes occur at different scales, with intricate interactions between levels and relatively distinct type of processes. To what extent actual urban dynamics include an actual strong coupling between scales, in the sense…

Physics and Society · Physics 2021-02-01 Juste Raimbault

Neural systems, artificial and biological, show similar representations of inputs when optimized to perform similar tasks. In visual systems optimized for tasks similar to object recognition, we propose that representation similarities…

Neurons and Cognition · Quantitative Biology 2023-12-15 Tahereh Toosi

Production plants today are becoming more and more complicated through more automation and networking. It is becoming more difficult for humans to participate, due to higher speed and decreasing reaction time of these plants. Tendencies to…

Multiagent Systems · Computer Science 2020-04-02 Bastian Deutschmann , Javad Ghofrani , Dirk Reichelt

Heterogeneity is one important feature of complex systems, leading to the complexity of their construction and analysis. Moving the heterogeneity at model level helps in mastering the difficulty of composing heterogeneous models which…

Software Engineering · Computer Science 2017-07-24 J. Christian Attiogbé

With the birth of quantum information science, many tools have been developed to deal with many-body quantum systems. Although a complete description of such systems is desirable, it will not always be possible to achieve this goal, as the…

Quantum Physics · Physics 2020-12-01 Cristhiano Duarte , Barbara Amaral , Marcelo Terra Cunha , Matthew Leifer
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