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We propose a new optimization framework for aleatoric uncertainty estimation in regression problems. Existing methods can quantify the error in the target estimation, but they tend to underestimate it. To obtain the predictive uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2021-03-12 Takumi Kawashima , Qing Yu , Akari Asai , Daiki Ikami , Kiyoharu Aizawa

Being able to adequately process and combine data arising from different sites is crucial in neuroimaging, but is difficult, owing to site, sequence and acquisition-parameter dependent biases. It is important therefore to design algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Pedro Borges , Richard Shaw , Thomas Varsavsky , Kerstin Klaser , David Thomas , Ivana Drobnjak , Sebastien Ourselin , M Jorge Cardoso

Learning a medical image segmentation model is an inherently ambiguous task, as uncertainties exist in both images (noise) and manual annotations (human errors and bias) used for model training. To build a trustworthy image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Xinyu Bai , Wenjia Bai

Surface normal estimation from a single image is an important task in 3D scene understanding. In this paper, we address two limitations shared by the existing methods: the inability to estimate the aleatoric uncertainty and lack of detail…

Computer Vision and Pattern Recognition · Computer Science 2021-09-22 Gwangbin Bae , Ignas Budvytis , Roberto Cipolla

Inverse problems, such as accelerated MRI reconstruction, are ill-posed and an infinite amount of possible and plausible solutions exist. This may not only lead to uncertainty in the reconstructed image but also in downstream tasks such as…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Jan Nikolas Morshuis , Matthias Hein , Christian F. Baumgartner

In recent years, machine learning has witnessed extensive adoption across various sectors, yet its application in medical image-based disease detection and diagnosis remains challenging due to distribution shifts in real-world data. In…

Machine Learning · Computer Science 2024-02-13 Masoumeh Javanbakhat , Md Tasnimul Hasan , Cristoph Lippert

Prediction uncertainty estimation has clinical significance as it can potentially quantify prediction reliability. Clinicians may trust 'blackbox' models more if robust reliability information is available, which may lead to more models…

Machine Learning · Computer Science 2022-10-04 Michael Dohopolski , Kai Wang , Biling Wang , Ti Bai , Dan Nguyen , David Sher , Steve Jiang , Jing Wang

Active learning (AL) has found wide applications in medical image segmentation, aiming to alleviate the annotation workload and enhance performance. Conventional uncertainty-based AL methods, such as entropy and Bayesian, often rely on an…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Siteng Ma , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Fully convolutional neural networks (FCNs), and in particular U-Nets, have achieved state-of-the-art results in semantic segmentation for numerous medical imaging applications. Moreover, batch normalization and Dice loss have been used…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Alireza Mehrtash , William M. Wells , Clare M. Tempany , Purang Abolmaesumi , Tina Kapur

Quality control (QC) of medical images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually at significant time and operator cost. We aim to…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Richard Shaw , Carole H. Sudre , Sebastien Ourselin , M. Jorge Cardoso

Semantic segmentation of medical images is an essential first step in computer-aided diagnosis systems for many applications. However, given many disparate imaging modalities and inherent variations in the patient data, it is difficult to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Bhavani Sambaturu , Ashutosh Gupta , C. V. Jawahar , Chetan Arora

Recently, deep convolutional neural networks have achieved great success for medical image segmentation. However, unlike segmentation of natural images, most medical images such as MRI and CT are volumetric data. In order to make full use…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Yichi Zhang , Qingcheng Liao , Le Ding , Jicong Zhang

In medical image segmentation, uncertainty estimates are often reported but rarely used to guide decisions. We study the missing step: how uncertainty maps are converted into actionable policies such as accepting, flagging, or deferring…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Saket Maganti

2D echocardiography is the most common imaging modality for cardiovascular diseases. The portability and relatively low-cost nature of Ultrasound (US) enable the US devices needed for performing echocardiography to be made widely available.…

Computer Vision and Pattern Recognition · Computer Science 2020-05-20 Lavsen Dahal , Aayush Kafle , Bishesh Khanal

Uncertainty quantification in inverse medical imaging tasks with deep learning has received little attention. However, deep models trained on large data sets tend to hallucinate and create artifacts in the reconstructed output that are not…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Max-Heinrich Laves , Malte Tölle , Tobias Ortmaier

We address the selection and evaluation of uncertain segmentation methods in medical imaging and present two case studies: prostate segmentation, illustrating that for minimal annotator variation simple deterministic models can suffice, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Kilian Zepf , Jes Frellsen , Aasa Feragen

Monte-Carlo (MC) Dropout provides a practical solution for estimating predictive distributions in deterministic neural networks. Traditional dropout, applied within the signal space, may fail to account for frequency-related noise common in…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Tal Zeevi , Lawrence H. Staib , John A. Onofrey

Recent developments in deep learning (DL) techniques have led to great performance improvement in medical image segmentation tasks, especially with the latest Transformer model and its variants. While labels from fusing multi-rater manual…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Parinaz Roshanzamir , Hassan Rivaz , Joshua Ahn , Hamza Mirza , Neda Naghdi , Meagan Anstruther , Michele C. Battié , Maryse Fortin , Yiming Xiao

Medical image segmentation is critical for clinical diagnosis, treatment planning, and monitoring, yet segmentation models often struggle with uncertainties stemming from occlusions, ambiguous boundaries, and variations in imaging devices.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Xiao Ma , Yuhui Tao , Zetian Zhang , Yuhan Zhang , Xi Wang , Sheng Zhang , Zexuan Ji , Yizhe Zhang , Qiang Chen , Guang Yang

With the rise of Deep Neural Networks, machine learning systems are nowadays ubiquitous in a number of real-world applications, which bears the need for highly reliable models. This requires a thorough look not only at the accuracy of such…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Pedro Conde , Tiago Barros , Rui L. Lopes , Cristiano Premebida , Urbano J. Nunes