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Medical image synthesis generates additional imaging modalities that are costly, invasive or harmful to acquire, which helps to facilitate the clinical workflow. When training pairs are substantially misaligned (e.g., lung MRI-CT pairs with…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Bowen Xin , Tony Young , Claire E Wainwright , Tamara Blake , Leo Lebrat , Thomas Gaass , Thomas Benkert , Alto Stemmer , David Coman , Jason Dowling

Magnetic Resonance (MR) Imaging and Computed Tomography (CT) are the primary diagnostic imaging modalities quite frequently used for surgical planning and analysis. A general problem with medical imaging is that the acquisition process is…

Image and Video Processing · Electrical Eng. & Systems 2020-06-08 Vismay Agrawal , Avinash Kori , Vikas Kumar Anand , Ganapathy Krishnamurthi

Compared to traditional methods, Deep Learning (DL) becomes a key technology for computer vision tasks. Synthetic data generation is an interesting use case for DL, especially in the field of medical imaging such as Magnetic Resonance…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Md Sumon Ali , Muzammil Behzad

Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , Xiu Li , Jayender Jagadeesan

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Medical Physics · Physics 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

In medical image synthesis, model training could be challenging due to the inconsistencies between images of different modalities even with the same patient, typically caused by internal status/tissue changes as different modalities are…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Hajar Emami , Ming Dong , Siamak Nejad-Davarani , Carri Glide-Hurst

In medical imaging, a general problem is that it is costly and time consuming to collect high quality data from healthy and diseased subjects. Generative adversarial networks (GANs) is a deep learning method that has been developed for…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Per Welander , Simon Karlsson , Anders Eklund

Deep learning (DL) has led to significant improvements in medical image synthesis, enabling advanced image-to-image translation to generate synthetic images. However, DL methods face challenges such as domain shift and high demands for…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Savannah P. Hays , Lianrui Zuo , Yihao Liu , Anqi Feng , Jiachen Zhuo , Jerry L. Prince , Aaron Carass

In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Medical Physics · Physics 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

Organ at Risk (OAR) segmentation from CT scans is a key component of the radiotherapy treatment workflow. In recent years, deep learning techniques have shown remarkable potential in automating this process. In this paper, we investigate…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Leonardo Crespi , Mattia Portanti , Daniele Loiacono

In biomedical image analysis, the applicability of deep learning methods is directly impacted by the quantity of image data available. This is due to deep learning models requiring large image datasets to provide high-level performance.…

Machine Learning · Computer Science 2023-08-14 Muhammad Muneeb Saad , Ruairi O'Reilly , Mubashir Husain Rehmani

In medical imaging, image synthesis is the estimation process of one image (sequence, modality) from another image (sequence, modality). Since images with different modalities provide diverse biomarkers and capture various features,…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Firoozeh Shomal Zadeh , Sevda Molani , Maysam Orouskhani , Marziyeh Rezaei , Mehrzad Shafiei , Hossein Abbasi

Medical image processing has been highlighted as an area where deep learning-based models have the greatest potential. However, in the medical field in particular, problems of data availability and privacy are hampering research progress…

Image and Video Processing · Electrical Eng. & Systems 2023-10-27 Christoph Angermann , Johannes Bereiter-Payr , Kerstin Stock , Markus Haltmeier , Gerald Degenhart

Deep learning has been extensively used in medical imaging applications, assuming that the test and training datasets belong to the same probability distribution. However, a common challenge arises when working with medical images generated…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Mohd Usama , Belal Ahmad , Christer Gronlund , Faleh Menawer R Althiyabi

With the development of image segmentation in computer vision, biomedical image segmentation have achieved remarkable progress on brain tumor segmentation and Organ At Risk (OAR) segmentation. However, most of the research only uses single…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Kuan-Lun Tseng , Winston Hsu , Chun-ting Wu , Ya-Fang Shih , Fan-Yun Sun

MR-only radiotherapy treatment planning requires accurate MR-to-CT synthesis. Current deep learning methods for MR-to-CT synthesis depend on pairwise aligned MR and CT training images of the same patient. However, misalignment between…

Computer Vision and Pattern Recognition · Computer Science 2017-08-04 Jelmer M. Wolterink , Anna M. Dinkla , Mark H. F. Savenije , Peter R. Seevinck , Cornelis A. T. van den Berg , Ivana Isgum

Online adaptive radiation therapy (ART) promises the ability to deliver an optimal treatment in response to daily patient anatomic variation. A major technical barrier for the clinical implementation of online ART is the requirement of…

Recently, the cycle-consistent generative adversarial networks (CycleGAN) has been widely used for synthesis of multi-domain medical images. The domain-specific nonlinear deformations captured by CycleGAN make the synthesized images…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Chengjia Wang , Gillian Macnaught , Giorgos Papanastasiou , Tom MacGillivray , David Newby

Electron density maps must be accurately estimated to achieve valid dose calculation in MR-only radiotherapy. The goal of this study is to assess whether two deep learning models, the conditional generative adversarial network (cGAN) and…

Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25…

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