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Reliable analysis of intracellular dynamic processes in time-lapse fluorescence microscopy images requires complete and accurate tracking of all small particles in all time frames of the image sequences. A fundamental first step towards…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Yao Yao , Ihor Smal , Ilya Grigoriev , Anna Akhmanova , Erik Meijering

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

As a hybrid imaging technology, photoacoustic microscopy (PAM) imaging suffers from noise due to the maximum permissible exposure of laser intensity, attenuation of ultrasound in the tissue, and the inherent noise of the transducer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Da He , Jiasheng Zhou , Xiaoyu Shang , Jiajia Luo , Sung-Liang Chen

Non-negative matrix factorization (NMF) is a dimensionality reduction technique that has shown promise for analyzing noisy data, especially astronomical data. For these datasets, the observed data may contain negative values due to noise…

Instrumentation and Methods for Astrophysics · Physics 2024-10-04 Dylan Green , Stephen Bailey

Non-negative Matrix Factorization (NMF) asks to decompose a (entry-wise) non-negative matrix into the product of two smaller-sized nonnegative matrices, which has been shown intractable in general. In order to overcome this issue, the…

Data Structures and Algorithms · Computer Science 2019-07-15 Zhihuai Chen , Yinan Li , Xiaoming Sun , Pei Yuan , Jialin Zhang

Color image denoising is frequently encountered in various image processing and computer vision tasks. One traditional strategy is to convert the RGB image to a less correlated color space and denoise each channel of the new space…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Yiwen Shan , Dong Hu , Zhi Wang , Tao Jia

The advancement of imaging devices and countless images generated everyday pose an increasingly high demand on image denoising, which still remains a challenging task in terms of both effectiveness and efficiency. To improve denoising…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Zhaoming Kong , Fangxi Deng , Haomin Zhuang , Jun Yu , Lifang He , Xiaowei Yang

Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Satu I. Inkinen , Mikael A. K. Brix , Miika T. Nieminen , Simon Arridge , Andreas Hauptmann

Calcium imaging permits optical measurement of neural activity. Since intracellular calcium concentration is an indirect measurement of neural activity, computational tools are necessary to infer the true underlying spiking activity from…

Machine Learning · Statistics 2017-11-07 Artur Speiser , Jinyao Yan , Evan Archer , Lars Buesing , Srinivas C. Turaga , Jakob H. Macke

Magnetic resonance imaging (MRI) is a non-invasive medical imaging technique offering high-resolution 3D images and valuable insights into human tissue conditions. Even at present, the refinement of denoising methods for MRI remains a…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Shiao Li

Calcium imaging is one of the most important tools in neurophysiology as it enables the observation of neuronal activity for hundreds of cells in parallel and at single-cell resolution. In order to use the data gained with calcium imaging,…

Neurons and Cognition · Quantitative Biology 2020-04-07 Elke Kirschbaum , Alberto Bailoni , Fred A. Hamprecht

The nonnegative matrix factorization (NMF) is widely used in signal and image processing, including bio-informatics, blind source separation and hyperspectral image analysis in remote sensing. A great challenge arises when dealing with a…

Computer Vision and Pattern Recognition · Computer Science 2016-03-29 Fei Zhu , Paul Honeine , Maya Kallas

Motivated by the analysis of high-dimensional neuroimaging signals located over the cortical surface, we introduce a novel Principal Component Analysis technique that can handle functional data located over a two-dimensional manifold. For…

Applications · Statistics 2019-08-02 Eardi Lila , John A. D. Aston , Laura M. Sangalli

We propose a flexible and theoretically supported framework for scalable nonnegative matrix factorization. The goal is to find nonnegative low-rank components directly from compressed measurements, accessing the original data only once or…

Optimization and Control · Mathematics 2026-02-17 Abraar Chaudhry , Elizaveta Rebrova

Non-negative matrix factorization (NMF) and non-negative tensor factorization (NTF) decompose non-negative high-dimensional data into non-negative low-rank components. NMF and NTF methods are popular for their intrinsic interpretability and…

Machine Learning · Computer Science 2024-12-02 Alexander Sietsema , Zerrin Vural , James Chapman , Yotam Yaniv , Deanna Needell

Image denoising is a fundamental operation in image processing and holds considerable practical importance for various real-world applications. Arguably several thousands of papers are dedicated to image denoising. In the past decade,…

Computer Vision and Pattern Recognition · Computer Science 2016-09-22 Wensen Feng , Peng Qiao , Xuanyang Xi , Yunjin Chen

Lossy image compression is essential for efficient transmission and storage. Traditional compression methods mainly rely on discrete cosine transform (DCT) or singular value decomposition (SVD), both of which represent image data in…

Image and Video Processing · Electrical Eng. & Systems 2025-03-28 Pooya Ashtari , Pourya Behmandpoor , Fateme Nateghi Haredasht , Jonathan H. Chen , Panagiotis Patrinos , Sabine Van Huffel

In this work, we consider nonnegative matrix factorization (NMF) with a regularization that promotes small volume of the convex hull spanned by the basis matrix. We present highly efficient algorithms for three different volume…

Numerical Analysis · Computer Science 2020-01-14 M. S. Ang , Nicolas Gillis

Typically, a medical image offers spatial information on the anatomy (and pathology) modulated by imaging specific characteristics. Many imaging modalities including Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) can be…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Agisilaos Chartsias , Thomas Joyce , Giorgos Papanastasiou , Michelle Williams , David Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

We investigate the sparse functional identification of complex cells and the decoding of visual stimuli encoded by an ensemble of complex cells. The reconstruction algorithm of both temporal and spatio-temporal stimuli is formulated as a…

Neurons and Cognition · Quantitative Biology 2017-06-20 Aurel A. Lazar , Nikul H. Ukani , Yiyin Zhou