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Radiomics-based machine learning models show promise for clinical decision support but are vulnerable to distribution shifts caused by variations in imaging protocols, positioning, and segmentation. This study systematically investigates…

Machine Learning · Computer Science 2025-10-30 Sarmad Ahmad Khan , Simon Bernatz , Zahra Moslehi , Florian Buettner

While remarkable advances have been made in Computed Tomography (CT), capturing CT images with non-standardized protocols causes low reproducibility regarding radiomic features, forming a barrier on CT image analysis in a large scale.…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Md Selim , Jie Zhang , Baowei Fei , Guo-Qiang Zhang , Jin Chen

Background: Radiogenomics allows identification of radiological biomarkers for genomic phenotypes. In glioblastoma, these biomarkers could potentially complement patient stratification strategies. We aim to develop and analytically validate…

Machine Learning · Computer Science 2026-05-12 Prajwal Ghimire , Junjie Li , Liu Yaou , Marc Modat , Thomas Booth

Image features need to be robust against differences in positioning, acquisition and segmentation to ensure reproducibility. Radiomic models that only include robust features can be used to analyse new images, whereas models with non-robust…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Alex Zwanenburg , Stefan Leger , Linda Agolli , Karoline Pilz , Esther G. C. Troost , Christian Richter , Steffen Löck

Outcome prediction is crucial for head and neck cancer patients as it can provide prognostic information for early treatment planning. Radiomics methods have been widely used for outcome prediction from medical images. However, these…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

Radiomics is a relatively new field which utilises automatically identified features from radiological scans. It has found a widespread application, particularly in oncology because many of the important oncological biomarkers are not…

Quantitative Methods · Quantitative Biology 2024-09-26 Stanislav Kozák

Magnetic resonance imaging (MRI) reconstruction is a fundamental task aimed at recovering high-quality images from undersampled or low-quality MRI data. This process enhances diagnostic accuracy and optimizes clinical applications. In…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Xiaoyan Kui , Zijie Fan , Zexin Ji , Qinsong Li , Chengtao Liu , Weixin Si , Beiji Zou

Early diagnosis of prostate cancer significantly improves a patient's 5-year survival rate. Biopsy of small prostate cancers is improved with image-guided biopsy. MRI-ultrasound fusion-guided biopsy is sensitive to smaller tumors but is…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Muhammad Imran , Brianna Nguyen , Jake Pensa , Sara M. Falzarano , Anthony E. Sisk , Muxuan Liang , John Michael DiBianco , Li-Ming Su , Yuyin Zhou , Wayne G. Brisbane , Wei Shao

Background and aim: This study aimed to predict methylation status of the O-6 methyl guanine-DNA methyl transferase (MGMT) gene promoter status by using MRI radiomics features, as well as univariate and multivariate analysis. Material and…

Magnetic Particle Imaging (MPI) is a tomographic imaging technique for determining the spatial distribution of superparamagnetic nanoparticles. Current MPI systems are capable of imaging iron masses over a wide dynamic range of more than…

Consistency and duplicability in Computed Tomography (CT) output is essential to quantitative imaging for lung cancer detection and monitoring. This study of CT-detected lung nodules investigated the reproducibility of volume-, density-,…

Breast X-ray CT imaging is being considered in screening as an extension to mammography. As a large fraction of the population will be exposed to radiation, low-dose imaging is essential. Iterative image reconstruction based on solving an…

Medical Physics · Physics 2011-11-14 Jakob H. Jørgensen , Emil Y. Sidky , Xiaochuan Pan

Longitudinal imaging analysis tracks disease progression and treatment response over time, providing dynamic insights into treatment efficacy and disease evolution. Radiomic features extracted from medical imaging can support the study of…

Applications · Statistics 2025-05-14 Isabella Cama , Michele Piana , Cristina Campi , Sara Garbarino

Magnetic resonance fingerprinting (MRF) provides a unique concept for simultaneous and fast acquisition of multiple quantitative MR parameters. Despite acquisition efficiency, adoption of MRF into the clinics is hindered by its dictionary…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Fabian Balsiger , Alain Jungo , Olivier Scheidegger , Pierre G. Carlier , Mauricio Reyes , Benjamin Marty

Hypertension is a medical condition that is well-established as a risk factor for many major diseases. For example, it can cause alterations in the cardiac structure and function over time that can lead to heart related morbidity and…

In many applications of tomography, the acquired projections are either limited in number or contain a significant amount of noise. In these cases, standard reconstruction methods tend to produce artifacts that can make further analysis…

Numerical Analysis · Mathematics 2016-04-11 D. M. Pelt , K. J. Batenburg

Radiomic representations can quantify properties of regions of interest in medical image data. Classically, they account for pre-defined statistics of shape, texture, and other low-level image features. Alternatively, deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Hongwei Li , Fei-Fei Xue , Krishna Chaitanya , Shengda Luo , Ivan Ezhov , Benedikt Wiestler , Jianguo Zhang , Bjoern Menze

While multislice electron ptychography can provide thermal-vibration limited resolution and 3D information, it relies on the proper selection of many intertwined experimental and computational parameters. Here, we outline a theoretical…

Materials Science · Physics 2023-11-28 Colin Gilgenbach , Xi Chen , James M. LeBeau

Purpose: This study examines the core traits of image-to-image translation (I2I) networks, focusing on their effectiveness and adaptability in everyday clinical settings. Methods: We have analyzed data from 794 patients diagnosed with…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Mohammad R. Salmanpour , Amin Mousavi , Yixi Xu , William B Weeks , Ilker Hacihaliloglu

A main barrier for the deployment of AI radiomic systems in clinical routine is their drop in performance under heterogeneous multicentre acquisition protocols. This work presents a performance-oriented framework for quantifying scan…

Artificial Intelligence · Computer Science 2026-05-15 D. Gil , I. Sanchez , C. Sanchez