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Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

The remarkable success of deep learning in recent years has prompted applications in medical image classification and diagnosis tasks. While classification models have demonstrated robustness in classifying simpler datasets like MNIST or…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Sushmita Sarker , Prithul Sarker , George Bebis , Alireza Tavakkoli

Humans are accustomed to environments that contain both regularities and exceptions. For example, at most gas stations, one pays prior to pumping, but the occasional rural station does not accept payment in advance. Likewise, deep neural…

Machine Learning · Computer Science 2021-06-16 Ziheng Jiang , Chiyuan Zhang , Kunal Talwar , Michael C. Mozer

This paper proposes a new way of regularizing an inverse problem in imaging (e.g., deblurring or inpainting) by means of a deep generative neural network. Compared to end-to-end models, such approaches seem particularly interesting since…

Computer Vision and Pattern Recognition · Computer Science 2021-01-22 Thomas Oberlin , Mathieu Verm

Score-based diffusion models demonstrate superior performance in generative tasks but encounter fundamental bottlenecks in inverse problems due to the analytical intractability of the time-dependent likelihood score. To bridge this gap, we…

Optimization and Control · Mathematics 2026-05-28 Boyang Zhang , Zhiguo Wang , Ya-Feng Liu

Generalist Anomaly Detection (GAD) aims to train a unified model on an original domain that can detect anomalies in new target domains. Previous GAD methods primarily use only normal samples as references, overlooking the valuable…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Yuexin Wang , Xiaolei Wang , Yizheng Gong , Jimin Xiao

Generative models are popular for medical imaging tasks such as anomaly detection, feature extraction, data visualization, or image generation. Since they are parameterized by deep learning models, they are often sensitive to distribution…

Machine Learning · Computer Science 2025-03-25 Miguel López-Pérez , Marco Miani , Valery Naranjo , Søren Hauberg , Aasa Feragen

We investigate the approximation efficiency of score functions by deep neural networks in diffusion-based generative modeling. While existing approximation theories utilize the smoothness of score functions, they suffer from the curse of…

Machine Learning · Computer Science 2023-09-21 Song Mei , Yuchen Wu

Graph anomaly detection (GAD) is a critical task in graph machine learning, with the primary objective of identifying anomalous nodes that deviate significantly from the majority. This task is widely applied in various real-world scenarios,…

Machine Learning · Computer Science 2025-07-03 Xiang Li , Jianpeng Qi , Zhongying Zhao , Guanjie Zheng , Lei Cao , Junyu Dong , Yanwei Yu

Anomaly detection on dynamic graphs refers to detecting entities whose behaviors obviously deviate from the norms observed within graphs and their temporal information. This field has drawn increasing attention due to its application in…

Machine Learning · Computer Science 2023-10-26 Shiqi Lou , Qingyue Zhang , Shujie Yang , Yuyang Tian , Zhaoxuan Tan , Minnan Luo

Probabilistic graphical models (PGMs) are widely used to discover latent structure in data, but their success hinges on selecting an appropriate model design. In practice, model specification is difficult and often requires iterative…

Machine Learning · Computer Science 2026-04-08 Kevin Zhang , Yixin Wang

Anomalies represent rare observations (e.g., data records or events) that deviate significantly from others. Over several decades, research on anomaly mining has received increasing interests due to the implications of these occurrences in…

Machine Learning · Computer Science 2022-04-21 Xiaoxiao Ma , Jia Wu , Shan Xue , Jian Yang , Chuan Zhou , Quan Z. Sheng , Hui Xiong , Leman Akoglu

Node outlier detection in attributed graphs is a challenging problem for which there is no method that would work well across different datasets. Motivated by the state-of-the-art results of score-based models in graph generative modeling,…

Machine Learning · Computer Science 2023-06-28 Dmitrii Gavrilev , Evgeny Burnaev

Deep generative models, such as Variational Autoencoders (VAEs) and Generative Adversarial Networks (GANs), have been employed widely in computational creativity research. However, such models discourage out-of-distribution generation to…

Computer Vision and Pattern Recognition · Computer Science 2022-05-27 Celia Cintas , Payel Das , Brian Quanz , Girmaw Abebe Tadesse , Skyler Speakman , Pin-Yu Chen

Reconstruction-based methods play an important role in unsupervised anomaly detection in images. Ideally, we expect a perfect reconstruction for normal samples and poor reconstruction for abnormal samples. Since the generalizability of deep…

Computer Vision and Pattern Recognition · Computer Science 2021-07-29 Jinlei Hou , Yingying Zhang , Qiaoyong Zhong , Di Xie , Shiliang Pu , Hong Zhou

Recent efforts towards video anomaly detection (VAD) try to learn a deep autoencoder to describe normal event patterns with small reconstruction errors. The video inputs with large reconstruction errors are regarded as anomalies at the test…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Yuandu Lai , Yahong Han , Yaowei Wang

We propose discriminative neighborhood smoothing of generative anomaly scores for anomalous sound detection. While the discriminative approach is known to achieve better performance than generative approaches often, we have found that it…

Audio and Speech Processing · Electrical Eng. & Systems 2024-03-19 Takuya Fujimura , Keisuke Imoto , Tomoki Toda

This paper addresses detecting anomalous patterns in images, time-series, and tensor data when the location and scale of the pattern is unknown a priori. The multiscale scan statistic convolves the proposed pattern with the image at various…

Statistics Theory · Mathematics 2018-06-22 James Sharpnack

We present a novel method for image anomaly detection, where algorithms that use samples drawn from some distribution of "normal" data, aim to detect out-of-distribution (abnormal) samples. Our approach includes a combination of encoder and…

Image and Video Processing · Electrical Eng. & Systems 2020-03-02 Nina Tuluptceva , Bart Bakker , Irina Fedulova , Anton Konushin

Recently, anomaly scores have been formulated using reconstruction loss of the adversarially learned generators and/or classification loss of discriminators. Unavailability of anomaly examples in the training data makes optimization of such…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Muhammad Zaigham Zaheer , Jin Ha Lee , Arif Mahmood , Marcella Astrid , Seung-Ik Lee