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We describe the Bedside Patient Rescue (BPR) project, the goal of which is risk prediction of adverse events for non-ICU patients using ~200 variables (vitals, lab results, assessments, ...). There are several missing predictor values for…

In Part I (arXiv:1911.00619) of this article, we proposed an importance sampling algorithm to compute rare-event probabilities in forward uncertainty quantification problems. The algorithm, which we termed the "Bayesian Inverse Monte Carlo…

Computation · Statistics 2019-11-06 Siddhant Wahal , George Biros

We consider a well defined joint detection and parameter estimation problem. By combining the Baysian formulation of the estimation subproblem with suitable constraints on the detection subproblem we develop optimum one- and two-step test…

Applications · Statistics 2011-01-27 George V. Moustakides , Guido H. Jajamovich , Ali Tajer , Xiaodong Wang

Models for analyzing multivariate data sets with missing values require strong, often unassessable, assumptions. The most common of these is that the mechanism that created the missing data is ignorable - a twofold assumption dependent on…

Applications · Statistics 2020-02-17 Iavor Bojinov , Natesh Pillai , Donald Rubin

Individual events at high-energy colliders like the LHC can be represented by a sequence of measurements, or 'point patterns' in an observable space. Starting from this data representation, we build a simple Bayesian probabilistic model for…

High Energy Physics - Phenomenology · Physics 2020-12-17 Darius A. Faroughy

In this paper, distributed Bayesian detection problems with unknown prior probabilities of hypotheses are considered. The sensors obtain observations which are conditionally dependent across sensors and their probability density functions…

Information Theory · Computer Science 2012-09-20 Xiaojing Shen , Pramod K. Varshney , Yunmin Zhu

Ideally, a meta-analysis will summarize data from several unbiased studies. Here we consider the less than ideal situation in which contributing studies may be compromised by measurement error. Measurement error affects every study design,…

Predictive mean matching (PMM) is a popular imputation strategy that imputes missing values by borrowing observed values from other cases with similar expectations. We show that, unlike other imputation strategies, PMM is not guaranteed to…

Methodology · Statistics 2025-07-01 Paul T. von Hippel

Background: Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies required in MR is often…

Methodology · Statistics 2021-12-16 Linyi Zou , Hui Guo , Carlo Berzuini

Meta-analyses of clinical trials targeting rare events face particular challenges when the data lack adequate numbers of events for all treatment arms. Especially when the number of studies is low, standard meta-analysis methods can lead to…

Applications · Statistics 2020-01-20 Burak Kürsad Günhan , Christian Röver , Tim Friede

Discovering statistically significant patterns from databases is an important challenging problem. The main obstacle of this problem is in the difficulty of taking into account the selection bias, i.e., the bias arising from the fact that…

Machine Learning · Statistics 2016-03-10 Shinya Suzumura , Kazuya Nakagawa , Mahito Sugiyama , Koji Tsuda , Ichiro Takeuchi

It is generally believed that more observations provide more information. However, we observe that in the independence test for rare events, the power of the test is, surprisingly, determined by the number of rare events rather than the…

Methodology · Statistics 2025-06-17 Danyang Huang , Liyuan Wang , Liping Zhu

Count outcomes in longitudinal studies are frequent in clinical and engineering studies. In frequentist and Bayesian statistical analysis, methods such as Mixed linear models allow the variability or correlation within individuals to be…

Methodology · Statistics 2024-07-15 Alejandra Estefanía Patiño Hoyos , Johnatan Cardona Jiménez

We develop a supervised machine learning model that detects anomalies in systems in real time. Our model processes unbounded streams of data into time series which then form the basis of a low-latency anomaly detection model. Moreover, we…

Machine Learning · Computer Science 2016-11-16 Derek Farren , Thai Pham , Marco Alban-Hidalgo

To address the challenges of imbalanced multi-class datasets typically used for rare event detection in critical cyber-physical systems, we propose an optimal, efficient, and adaptable mixed integer programming (MIP) ensemble weighting…

Machine Learning · Computer Science 2025-04-16 Georgios Tertytchny , Georgios L. Stavrinides , Maria K. Michael

In this note, an alternative for presenting the distribution of `significant' events in searches for new phenomena is described. The alternative is based on probability density functions used in the evaluation of the `significance' of an…

High Energy Physics - Experiment · Physics 2019-02-25 Nicholas Wardle

This paper addresses the problem of detecting anomalous activity in traffic networks where the network is not directly observed. Given knowledge of what the node-to-node traffic in a network should be, any activity that differs…

Methodology · Statistics 2019-02-20 Elizabeth Hou , Yasin Yilmaz , Alfred Hero

The widespread adoption of online randomized controlled experiments (A/B Tests) for decision-making has created ongoing capacity constraints which necessitate interim analyses. As a consequence, platform users are increasingly motivated to…

Applications · Statistics 2025-11-11 Abbas Zaidi , Rina Friedberg , Samir Khan , Yao-Yang Leow , Maulik Soneji , Houssam Nassif , Richard Mudd

In this paper we present an application of techniques from statistical signal processing to the problem of event detection in wireless sensor networks used for environmental monitoring. The proposed approach uses the well-established…

Networking and Internet Architecture · Computer Science 2009-01-27 Jayant Gupchup , Andreas Terzis , Randal Burns , Alex Szalay

Traditionally, research in Business Process Management has put a strong focus on centralized and intra-organizational processes. However, today's business processes are increasingly distributed, deviating from a centralized layout, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-01-10 Michael Borkowski , Walid Fdhila , Matteo Nardelli , Stefanie Rinderle-Ma , Stefan Schulte