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Obtaining accurate forecasts for the evolution of epidemic outbreaks from deterministic compartmental models represents a major theoretical challenge. Recently, it has been shown that these models typically exhibit trajectories' degeneracy,…

Two simple agent based models are often employed in epidemic studies: the susceptible-infected (SI) and the susceptible-infected-susceptible (SIS). Both models describe the time evolution of infectious diseases in networks in which vertices…

Epidemic models often reflect characteristic features of infectious spreading processes by coupled non-linear differential equations considering different states of health (such as Susceptible, Infected, or Recovered). This compartmental…

Physics and Society · Physics 2021-12-01 Vaiva Vasiliauskaite , Nino Antulov-Fantulin , Dirk Helbing

This article explores mathematical models for understanding the evolution of contagious diseases. The most widely known set of models are the compartmental ones, which are based on a set of differential equations. But these are not the only…

Populations and Evolution · Quantitative Biology 2021-12-07 C. O. S. Sorzano

In this survey we report some recent results in the mathematical modeling of epidemic phenomena through the use of kinetic equations. We initially consider models of interaction between agents in which social characteristics play a key role…

Populations and Evolution · Quantitative Biology 2023-09-11 Giacomo Albi , Giulia Bertaglia , Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi , Giuseppe Toscani , Mattia Zanella

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

Populations and Evolution · Quantitative Biology 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

We present an epidemiological compartment model, SAIR(S), that explicitly captures the dynamics of asymptomatic infected individuals in an epidemic spread process. We first present a group model and then discuss networked versions. We…

Populations and Evolution · Quantitative Biology 2021-03-23 Xiaoqi Bi , Carolyn L. Beck

Effective intervention strategies for epidemics rely on the identification of their origin and on the robustness of the predictions made by network disease models. We introduce a Bayesian uncertainty quantification framework to infer model…

Populations and Evolution · Quantitative Biology 2020-04-02 Karen Larson , Clark Bowman , Zhizhong Chen , Panagiotis Hadjidoukas , Costas Papadimitriou , Petros Koumoutsakos , Anastasios Matzavinos

The spreading of epidemics is very much determined by the structure of the contact network, which may be impacted by the mobility dynamics of the individuals themselves. In confined scenarios where a small, closed population spends most of…

Physics and Society · Physics 2018-05-09 Clara Granell , Peter J. Mucha

Mathematical modeling of epidemic propagation on networks is extended to hypergraphs in order to account for both the community structure and the nonlinear dependence of the infection pressure on the number of infected neighbours. The exact…

Dynamical Systems · Mathematics 2016-10-31 Ágnes Bodó , Gyula Y. Katona , Péter L. Simon

The susceptible-infected-susceptible (SIS) agent-based model is usually employed in the investigation of epidemics. The model describes a Markov process for a single communicable disease among susceptible (S) and infected (I) agents.…

Physics and Society · Physics 2016-09-28 Gilberto M. Nakamura , Alexandre S. Martinez

The compartmental models used to study epidemic spreading often assume the same susceptibility for all individuals, and are therefore, agnostic about the effects that differences in susceptibility can have on epidemic spreading. Here we…

Physics and Society · Physics 2014-03-12 Daniel Smilkov , Cesar A. Hidalgo , Ljupco Kocarev

Epidemiological compartmental models are useful for understanding infectious disease propagation and directing public health policy decisions. Calibration of these models is an important step in offering accurate forecasts of disease…

Machine Learning · Computer Science 2023-12-12 Nikunj Gupta , Anh Mai , Azza Abouzied , Dennis Shasha

Sequential Monte Carlo (SMC) algorithms represent a suite of robust computational methodologies utilized for state estimation and parameter inference within dynamical systems, particularly in real-time or online environments where data…

Uncertainty can be classified as either aleatoric (intrinsic randomness) or epistemic (imperfect knowledge of parameters). The majority of frameworks assessing infectious disease risk consider only epistemic uncertainty. We only ever…

Compartmental models are widely adopted to describe and predict the spreading of infectious diseases. The unknown parameters of such models need to be estimated from the data. Furthermore, when some of the model variables are not…

Physics and Society · Physics 2021-01-18 Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

The Susceptible-Infected-Susceptible model is a canonical model for emerging disease outbreaks. Such outbreaks are naturally modeled as taking place on networks. A theoretical challenge in network epidemiology is the dynamic correlations…

Physics and Society · Physics 2016-06-29 Chao-Ran Cai , Zhi-Xi Wu , Michael Z. Q. Chen , Petter Holme , Jian-Yue Guan

We predict the future course of ongoing susceptible-infected-susceptible (SIS) epidemics on regular, Erd\H{o}s-R\'{e}nyi and Barab\'asi-Albert networks. It is known that the contact network influences the spread of an epidemic within a…

Populations and Evolution · Quantitative Biology 2021-11-11 Tanja Zerenner , Francesco Di Lauro , Masoumeh Dashti , Luc Berthouze , Istvan Z. Kiss
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