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The class of non-rigid registration methods proposed in the framework of PDE-constrained Large Deformation Diffeomorphic Metric Mapping is a particularly interesting family of physically meaningful diffeomorphic registration methods.…

Optimization and Control · Mathematics 2018-08-01 Monica Hernandez

The family of PDE-constrained LDDMM methods is emerging as a particularly interesting approach for physically meaningful diffeomorphic transformations. The original combination of Gauss--Newton--Krylov optimization and Runge--Kutta…

Numerical Analysis · Mathematics 2020-06-15 Monica Hernandez

We propose numerical algorithms for solving large deformation diffeomorphic image registration problems. We formulate the nonrigid image registration problem as a problem of optimal control. This leads to an infinite-dimensional partial…

Numerical Analysis · Mathematics 2015-05-08 Andreas Mang , George Biros

Diffeomorphic registration using optimal control on the diffeomorphism group and on shape spaces has become widely used since the development of the Large Deformation Diffeomorphic Metric Mapping (LDDMM) algorithm. More recently, a series…

Optimization and Control · Mathematics 2015-03-04 Sylvain Arguillère , Michael Miller , Laurent Younes

We present an efficient solver for diffeomorphic image registration problems in the framework of Large Deformations Diffeomorphic Metric Mappings (LDDMM). We use an optimal control formulation, in which the velocity field of a hyperbolic…

Computer Vision and Pattern Recognition · Computer Science 2017-11-02 Andreas Mang , Lars Ruthotto

Many physics-informed machine learning methods for PDE-based problems rely on Gaussian processes (GPs) or neural networks (NNs). However, both face limitations when data are scarce and the dimensionality is high. Although GPs are known for…

Machine Learning · Computer Science 2025-01-31 Weihao Yan , Christoph Brune , Mengwu Guo

In deformable registration, the geometric framework - large deformation diffeomorphic metric mapping or LDDMM, in short - has inspired numerous techniques for comparing, deforming, averaging and analyzing shapes or images. Grounded in…

Artificial Intelligence · Computer Science 2022-05-11 Boulbaba Ben Amor , Sylvain Arguillère , Ling Shao

In computational anatomy, the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework has become a central tool for modeling smooth, invertible transformations between shapes such as curves or landmarks. In this paper, we extend…

Differential Geometry · Mathematics 2025-11-19 Rayane Mouhli , Thomas Pierron

We introduce a region-specific diffeomorphic metric mapping (RDMM) registration approach. RDMM is non-parametric, estimating spatio-temporal velocity fields which parameterize the sought-for spatial transformation. Regularization of these…

Computer Vision and Pattern Recognition · Computer Science 2019-11-12 Zhengyang Shen , François-Xavier Vialard , Marc Niethammer

The space mapping technique is used to efficiently solve complex optimization problems. It combines the accuracy of fine model simulations with the speed of coarse model optimizations to approximate the solution of the fine model…

Optimization and Control · Mathematics 2025-10-14 Sebastian Blauth

In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Alexis Arnaudon , Darryl D. Holm , Akshay Pai , Stefan Sommer

We propose regularization schemes for deformable registration and efficient algorithms for their numerical approximation. We treat image registration as a variational optimal control problem. The deformation map is parametrized by its…

Optimization and Control · Mathematics 2016-09-09 Andreas Mang , George Biros

Lagrangian particle formulations of the large deformation diffeomorphic metric mapping algorithm (LDDMM) only allow for the study of a single shape. In this paper, we introduce and discuss both a theoretical and practical setting for the…

Optimization and Control · Mathematics 2015-03-04 Sylvain Arguillère , Emmanuel Trélat , Alain Trouvé , Laurent Younes

Dynamic Mode Decomposition (DMD) is a powerful tool for extracting spatial and temporal patterns from multi-dimensional time series, and it has been used successfully in a wide range of fields, including fluid mechanics, robotics, and…

Dynamical Systems · Mathematics 2021-09-07 Ziyou Wu , Steven L. Brunton , Shai Revzen

Cardiac deformation is a crucial biomarker for the evaluation of cardiac function. Current methods for estimating cardiac strain might underestimate local deformation due to through-plane motion and segmental averaging. Mesh-based mapping…

Tissues and Organs · Quantitative Biology 2025-04-07 Beatrice Moscoloni , Patrick Segers , Mathias Peirlinck

Anatomy is undergoing a renaissance driven by availability of large digital data sets generated by light microscopy. A central computational task is to map individual data volumes to standardized templates. This is accomplished by…

Image and Video Processing · Electrical Eng. & Systems 2018-09-19 Daniel J. Tward , Partha Mitra , Michael I. Miller

In this paper, we present numerical methods suitable for solving convex quadratic Fractional Differential Equation (FDE) constrained optimization problems, with box constraints on the state and/or control variables. We develop an…

Optimization and Control · Mathematics 2021-02-01 Spyridon Pougkakiotis , John W. Pearson , Santolo Leveque , Jacek Gondzio

Diffeomorphic registration frameworks such as Large Deformation Diffeomorphic Metric Mapping (LDDMM) are used in computer graphics and the medical domain for atlas building, statistical latent modeling, and pairwise and groupwise…

Image and Video Processing · Electrical Eng. & Systems 2024-07-31 Sven Dummer , Nicola Strisciuglio , Christoph Brune

We propose a PDE-constrained shape registration algorithm that captures the deformation and growth of biological tissue from imaging data. Shape registration is the process of evaluating optimum alignment between pairs of geometries through…

Biological Physics · Physics 2022-04-07 Aishwarya Pawar , Linlin Li , Arun K Gosain , David M Umulis , Adrian B Tepole

Deterministic approaches using iterative optimisation have been historically successful in diffeomorphic image registration (DiffIR). Although these approaches are highly accurate, they typically carry a significant computational burden.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Alexander Thorley , Xi Jia , Hyung Jin Chang , Boyang Liu , Karina Bunting , Victoria Stoll , Antonio de Marvao , Declan P. O'Regan , Georgios Gkoutos , Dipak Kotecha , Jinming Duan
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