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We investigate general properties of non-deterministic self-assembly with asymmetric interactions, using a computational model and DNA tile assembly experiments. By contrasting symmetric and asymmetric interactions we show that the latter…

Soft Condensed Matter · Physics 2016-08-24 S. Tesoro , K. Göpfrich , T. Kartanas , U. F. Keyser , S. E. Ahnert

Experiments have reached a monumental capacity for designing and synthesizing microscopic particles for self-assembly, making it possible to precisely control particle concentrations, shapes, and interactions. However, more physical insight…

Soft Condensed Matter · Physics 2026-02-19 Maximilian C. Hübl , Thomas E. Videbæk , Daichi Hayakawa , W. Benjamin Rogers , Carl P. Goodrich

The trade-off between strength and ductility has plagued the design of macroscopic assemblies of two-dimensional materials for a long time. In order to break the strength-ductility paradox, the design of self-folded two-dimensional…

Materials Science · Physics 2021-12-08 Anran Wei , Fenglin Guo

Biological systems exploit self-assembly to create complex structures whose arrangements are finely controlled from molecular to mesoscopic level. Herein we report an example of using fully synthetic systems that mimic two levels of…

Living cells dynamically modulate the local morphologies of their actin cytoskeletons to perform biological functions, including force transduction, intracellular transport, and cell division. A major challenge is to understand how diverse…

Biological Physics · Physics 2018-12-07 Simon L. Freedman , Glen M. Hocky , Shiladitya Banerjee , Aaron R. Dinner

The study of elastic structures embedded with fluid-filled cavities received considerable attention in fields such as autonomous materials, sensors, actuators, and smart systems. This work studies an elastic beam embedded with a set of…

Fluid Dynamics · Physics 2021-12-06 Yoav Matia , Amir D. Gat

In the age of artificial intelligence and biotechnology, a unified understanding of technology and biology is critically needed but still lacking. A cornerstone of such unification is evolvable design. I present a formalism, called goal…

Physics and Society · Physics 2025-07-15 Dániel Czégel

We describe some of the important physical characteristics of the `pathways', i.e. dynamical processes, by which molecular, nanoscale and micron-scale self-assembly occurs. We highlight the fact that there exist features of self-assembly…

Statistical Mechanics · Physics 2016-03-22 Stephen Whitelam , Robert L. Jack

We discuss the phenomenon of spontaneous self-compactification in a model colloidal system, proposed in a recent work on DNA-mediated self-assembly. We focus on the effect of thermal fluctuations on the stability of membrane-like…

Soft Condensed Matter · Physics 2007-05-23 Juyong Park , Alexei V. Tkachenko

Inspired by protein folding, we explored the construction of three-dimensional structures and machines from one-dimensional chains of simple building blocks. This approach not only allows us to recreate the self-replication mechanism…

Computation and Language · Computer Science 2024-08-15 Ralph P. Lano

Self-assembly is traditionally described as the process through which an initially disordered system relaxes towards an equilibrium ordered phase only driven by local interactions between its building blocks. However, This definition is too…

Soft Condensed Matter · Physics 2015-06-15 Lorenzo Di Michele , Francesco Varrato , Jurij Kotar , Simon H. Nathan , Giuseppe Foffi , Erika Eiser

Imagine a robot that can assemble a functional product from the individual parts presented in any configuration to the robot. Designing such a robotic system is a complex problem which presents several open challenges. To bypass these…

Self-assembly is a key process in living systems - from the microscopic biological level (e.g. assembly of proteins into fibrils within biomolecular condensates in a human cell) through to the macroscopic societal level (e.g. assembly of…

Biological Physics · Physics 2023-12-15 Pedro D. Manrique , Frank Yingjie Huo , Sara El Oud , Neil F. Johnson

A hallmark of living systems is the ability to employ a common set of versatile building blocks that can self-organize into a multitude of different structures, in a way that can be controlled with minimal cost. This capability can only be…

Statistical Mechanics · Physics 2022-01-26 Saeed Osat , Ramin Golestanian

Building structures with hierarchical order through the self-assembly of smaller blocks is not only a prerogative of nature, but also a strategy to design artificial materials with tailored functions. We explore in simulation the…

Soft Condensed Matter · Physics 2020-02-17 Santi Prestipino , Domenico Gazzillo , Gianmarco Munaò , Dino Costa

In this work, we propose a framework called Auto-Assembly for automated robotic assembly from design files and demonstrate a practical implementation on modular parts joined by fastening using a robotic cell consisting of two robots. We…

Robotics · Computer Science 2023-01-09 Sergei Zobov , Fedor Chervinskii , Aleksandr Rybnikov , Danil Petrov , Komal Vendidandi

This perspective will overview an emerging paradigm for self-organized soft materials, {\it geometrically-frustrated assemblies}, where interactions between self-assembling elements (e.g. particles, macromolecules, proteins) favor local…

Soft Condensed Matter · Physics 2016-09-20 Gregory M. Grason

Tile displacement is a newly-recognized mechanism in DNA nanotechnology that exploits principles analogous to toehold-mediated strand displacement but within the context of self-assembled DNA origami tile arrays. Here, we formulate an…

Emerging Technologies · Computer Science 2023-01-06 Erik Winfree , Lulu Qian

Non-equilibrium assembly, driven by fluxes controllable by continuous external energy inputs, enables dynamic and reconfigurable structures. Such controlled 3D assembly is desired for the design of adaptive materials that exploit…

Soft Condensed Matter · Physics 2024-12-17 Desmond J. Quinn , Diptabrata Paul , Frank Cichos

Three-dimensional self-assembly of lithographically patterned ultrathin films opens a path to manufacture microelectronic architectures with functionalities and integration schemes not accessible by conventional two-dimensional…