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Medical image segmentation plays a critical role in clinical decision-making, treatment planning, and disease monitoring. However, accurate segmentation of medical images is challenging due to several factors, such as the lack of…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Zihan Li , Yuan Zheng , Xiangde Luo , Dandan Shan , Qingqi Hong

Cardiac segmentation is an essential step for the diagnosis of cardiovascular diseases. However, pixel-wise dense labeling is both costly and time-consuming. Scribble, as a form of sparse annotation, is more accessible than full…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Ke Zhang , Xiahai Zhuang

Curating fully annotated datasets for medical image segmentation is labour-intensive and expertise-demanding. To alleviate this problem, prior studies have explored scribble annotations for weakly supervised segmentation. Existing solutions…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Ke Zhang , Bomin Wang , Hangqi Zhou , Xiahai Zhuang

High-quality pixel-level annotations of medical images are essential for supervised segmentation tasks, but obtaining such annotations is costly and requires medical expertise. To address this challenge, we propose a novel coarse-to-fine…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Anghong Du , Nay Aung , Theodoros N. Arvanitis , Stefan K. Piechnik , Joao A C Lima , Steffen E. Petersen , Le Zhang

Scribble supervision, a common form of weakly supervised learning, involves annotating pixels using hand-drawn curve lines, which helps reduce the cost of manual labelling. This technique has been widely used in medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jing Yuan , Tania Stathaki

Although deep learning can provide promising results in medical image analysis, the lack of very large annotated datasets confines its full potential. Furthermore, limited positive samples also create unbalanced datasets which limit the…

Computer Vision and Pattern Recognition · Computer Science 2018-05-09 Ken C. L. Wong , Alexandros Karargyris , Tanveer Syeda-Mahmood , Mehdi Moradi

Curating a large set of fully annotated training data can be costly, especially for the tasks of medical image segmentation. Scribble, a weaker form of annotation, is more obtainable in practice, but training segmentation models from…

Image and Video Processing · Electrical Eng. & Systems 2022-03-15 Ke Zhang , Xiahai Zhuang

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Sota Kato , Kazuhiro Hotta

Medical image segmentation methods typically rely on numerous dense annotated images for model training, which are notoriously expensive and time-consuming to collect. To alleviate this burden, weakly supervised techniques have been…

Computer Vision and Pattern Recognition · Computer Science 2022-12-26 Qing En , Yuhong Guo

The need for labour intensive pixel-wise annotation is a major limitation of many fully supervised learning methods for segmenting bioimages that can contain numerous object instances with thin separations. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Peter Schuetz , Carola-Bibiane Schönlieb

Annotation of medical images has been a major bottleneck for the development of accurate and robust machine learning models. Annotation is costly and time-consuming and typically requires expert knowledge, especially in the medical domain.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Holger Roth , Ling Zhang , Dong Yang , Fausto Milletari , Ziyue Xu , Xiaosong Wang , Daguang Xu

Segmentation in medical imaging is an essential and often preliminary task in the image processing chain, driving numerous efforts towards the design of robust segmentation algorithms. Supervised learning methods achieve excellent…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Pierre Rougé , Pierre-Henri Conze , Nicolas Passat , Odyssée Merveille

Medical experts often manually segment images to obtain diagnostic statistics and discard the resulting annotations. We aim to train segmentation models to alleviate this burden, but constrained to the retained summary statistics (e.g., the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Omkar Kulkarni , Edward Raff , Tim Oates

Large annotated datasets are vital for training segmentation models, but pixel-level labeling is time-consuming, error-prone, and often requires scarce expert annotators, especially in medical imaging. In contrast, coarse annotations are…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Le Zhang , Fuping Wu , Arun Thirunavukarasu , Kevin Bronik , Thomas Nichols , Bartlomiej W. Papiez

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Deep learning methods are the de-facto solutions to a multitude of medical image analysis tasks. Cardiac MRI segmentation is one such application which, like many others, requires a large number of annotated data so a trained network can…

Image and Video Processing · Electrical Eng. & Systems 2022-01-02 Youssef Skandarani , Pierre-Marc Jodoin , Alain Lalande

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Curating large-scale fully annotated datasets is expensive, laborious, and cumbersome, especially for medical images. Several methods have been proposed in the literature that make use of weak annotations in the form of scribbles. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Ke Zhang , Vishal M. Patel

Deep convolutional neural networks have driven substantial advancements in the automatic understanding of images. Requiring a large collection of images and their associated annotations is one of the main bottlenecks limiting the adoption…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Zahra Mirikharaji , Yiqi Yan , Ghassan Hamarneh

Although deep convolutional networks have reached state-of-the-art performance in many medical image segmentation tasks, they have typically demonstrated poor generalisation capability. To be able to generalise from one domain (e.g. one…

Computer Vision and Pattern Recognition · Computer Science 2020-11-05 Reuben Dorent , Samuel Joutard , Jonathan Shapey , Sotirios Bisdas , Neil Kitchen , Robert Bradford , Shakeel Saeed , Marc Modat , Sebastien Ourselin , Tom Vercauteren