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In this paper we apply new geometric and combinatorial methods to the study of phylogenetic mixtures. The focus of the geometric approach is to describe the geometry of phylogenetic mixture distributions for the two state random cluster…

Populations and Evolution · Quantitative Biology 2007-11-08 Frederick A. Matsen , Elchanan Mossel , Mike Steel

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Most data in genome-wide phylogenetic analysis (phylogenomics) is essentially multidimensional, posing a major challenge to human comprehension and computational analysis. Also, we can not directly apply statistical learning models in data…

Combinatorics · Mathematics 2020-03-26 Xiaoxian Tang , Houjie Wang , Ruriko Yoshida

The tree metric theorem provides a combinatorial four point condition that characterizes dissimilarity maps derived from pairwise compatible split systems. A similar (but weaker) four point condition characterizes dissimilarity maps derived…

Combinatorics · Mathematics 2011-10-24 Aaron Kleinman , Matan Harel , Lior Pachter

We introduce a correspondence between phylogenetic trees and Brauer diagrams, inspired by links between binary trees and matchings described by Diaconis and Holmes (1998). This correspondence gives rise to a range of semigroup structures on…

Populations and Evolution · Quantitative Biology 2022-10-12 Andrew Francis , Peter D Jarvis

Hyperbolic space naturally encodes hierarchical structures such as phylogenies (binary trees), where inward-bending geodesics reflect paths through least common ancestors, and the exponential growth of neighborhoods mirrors the…

Machine Learning · Computer Science 2025-07-17 Alex Chen , Philipe Chlenski , Kenneth Munyuza , Antonio Khalil Moretti , Christian A. Naesseth , Itsik Pe'er

Using the wedge sum of metric spaces, for all compact metrizable spaces, we construct a topological embedding of the compact metrizable space into the set of all metric trees in the Gromov--Hausdorff space with finite prescribed values. As…

Metric Geometry · Mathematics 2021-12-13 Yoshito Ishiki

We introduce new methods for phylogenetic tree quartet construction by using machine learning to optimize the power of phylogenetic invariants. Phylogenetic invariants are polynomials in the joint probabilities which vanish under a model of…

Populations and Evolution · Quantitative Biology 2007-05-23 Nicholas Eriksson , Yuan Yao

In this paper we examine the relationship between hyperconvex hulls and metric trees. After providing a linking construction for hyperconvex spaces, we show that the four-point property is inherited by the hyperconvex hull, which leads to…

Metric Geometry · Mathematics 2007-05-23 A. G. Aksoy , B. Maurizi

We compare the phylogenetic tensors for various trees and networks for two, three and four taxa. If the probability spaces between one tree or network and another are not identical then there will be phylogenetic tensors that could have…

Populations and Evolution · Quantitative Biology 2016-06-24 Jonathan Mitchell

Motivated by applications to low-rank matrix completion, we give a combinatorial characterization of the independent sets in the algebraic matroid associated to the collection of $m\times n$ rank-2 matrices and $n\times n$ skew-symmetric…

Combinatorics · Mathematics 2017-07-17 Daniel Irving Bernstein

A widely used method for determining the similarity of two labeled trees is to compute a maximum agreement subtree of the two trees. Previous work on this similarity measure is only concerned with the comparison of labeled trees of two…

Computer Vision and Pattern Recognition · Computer Science 2007-05-23 Ming-Yang Kao , Tak-Wah Lam , Wing-Kin Sung , Hing-Fung Ting

The inference of evolutionary histories is a central problem in evolutionary biology. The analysis of a sample of phylogenetic trees can be conducted in Billera-Holmes-Vogtmann tree space, which is a CAT(0) metric space of phylogenetic…

Statistics Theory · Mathematics 2025-10-22 Yuki Takazawa , Tomonari Sei

In 1996, Bodlaender showed the celebrated result that an optimal tree decomposition of a graph of bounded treewidth can be found in linear time. The algorithm is based on an algorithm of Bodlaender and Kloks that computes an optimal tree…

Data Structures and Algorithms · Computer Science 2020-03-19 Ernst Althaus , Sarah Ziegler

The ongoing explosion of genome sequence data is transforming how we reconstruct and understand the histories of biological systems. Across biological scales, from individual cells to populations and species, trees-based models provide a…

Populations and Evolution · Quantitative Biology 2025-12-08 Yun Deng , Shing H. Zhan , Yulin Zhang , Chao Zhang , Bingjie Chen

A Supertree synthesizes the topologies of a set of phylogenetic trees carrying overlapping taxa set. In process, conflicts in the tree topologies are aimed to be resolved with the consensus clades. Such a problem is proved to be NP-hard.…

Populations and Evolution · Quantitative Biology 2016-11-01 Sourya Bhattacharyya , Jayanta Mukhopadhyay

The problem of realizing finite metric spaces in terms of weighted graphs has many applications. For example, the mathematical and computational properties of metrics that can be realized by trees have been well-studied and such research…

Combinatorics · Mathematics 2020-02-10 Momoko Hayamizu , Katharina T. Huber , Vincent Moulton , Yukihiro Murakami

Phylogenetic tree shapes capture fundamental signatures of evolution. We consider ``ranked'' tree shapes, which are equipped with a total order on the internal nodes compatible with the tree graph. Recent work has established an elegant…

Populations and Evolution · Quantitative Biology 2026-03-10 Chris Jennings-Shaffer , Ziyue , Chen , Julia A Palacios , Frederick A Matsen

Contour trees describe the topology of level sets in scalar fields and are widely used in topological data analysis and visualization. A main challenge of utilizing contour trees for large-scale scientific data is their computation at scale…

Computational Geometry · Computer Science 2024-10-01 Mingzhe Li , Hamish Carr , Oliver Rübel , Bei Wang , Gunther H. Weber

Algorithms for binary classification based on adaptive tree partitioning are formulated and analyzed for both their risk performance and their friendliness to numerical implementation. The algorithms can be viewed as generating a set…

Statistics Theory · Mathematics 2014-11-05 Peter Binev , Albert Cohen , Wolfgang Dahmen , Ronald DeVore
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