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Ordinary differential equations (ODEs) are widely used to model biological, (bio-)chemical and technical processes. The parameters of these ODEs are often estimated from experimental data using ODE-constrained optimisation. This article…

Optimization and Control · Mathematics 2015-11-06 Anna Fiedler , Fabian J. Theis , Jan Hasenauer

We propose the Sequential Synthetic Difference-in-Differences (Sequential SDiD) estimator for event studies with staggered treatment adoption, particularly when the parallel trends assumption fails. The method uses an iterative imputation…

Econometrics · Economics 2025-06-23 Dmitry Arkhangelsky , Aleksei Samkov

A new simulation package, GSEIM, for solving a set of ordinary differential equations is presented. The organisation of the program is illustrated with the help of a block diagram. Various features of GSEIM are discussed. Two ways of…

Computational Engineering, Finance, and Science · Computer Science 2021-04-15 Mahesh B. Patil , Ruchita D. Korgaonkar , Kumar Appaiah

The differentiable programming paradigm is a cornerstone of modern scientific computing. It refers to numerical methods for computing the gradient of a numerical model's output. Many scientific models are based on differential equations,…

Sparse spectral methods for solving partial differential equations have been derived in recent years using hierarchies of classical orthogonal polynomials on intervals, disks, and triangles. In this work we extend this methodology to a…

Numerical Analysis · Mathematics 2020-01-17 Ben Snowball , Sheehan Olver

Asymptotic goodness-of-fit methods in contingency table analysis can struggle with sparse data, especially in multi-way tables where it can be infeasible to meet sample size requirements for a robust application of distributional…

Methodology · Statistics 2023-12-29 Shishir Agrawal , Luis David Garcia Puente , Minho Kim , Flavia Sancier-Barbosa

Fundamentals on Lie group methods and applications to differential equations are surveyed. Many examples are included to elucidate their extensive applicability for analytically solving both ordinary and partial differential equations.

Classical Analysis and ODEs · Mathematics 2025-04-18 F. Güngör

Parameter inference for stochastic differential equation mixed effects models (SDEMEMs) is a challenging problem. Analytical solutions for these models are rarely available, which means that the likelihood is also intractable. In this case,…

Computation · Statistics 2019-09-30 Imke Botha , Robert Kohn , Christopher Drovandi

Discovering patterns of the complex high-dimensional data is a long-standing problem. Dimension Reduction (DR) and Intrinsic Dimension Estimation (IDE) are two fundamental thematic programs that facilitate geometric understanding of the…

Machine Learning · Statistics 2022-09-13 Kisung You

The numerical solution of differential equations can be formulated as an inference problem to which formal statistical approaches can be applied. However, nonlinear partial differential equations (PDEs) pose substantial challenges from an…

Numerical Analysis · Mathematics 2021-08-26 Junyang Wang , Jon Cockayne , Oksana Chkrebtii , T. J. Sullivan , Chris. J. Oates

A new numerical method for solving a scalar ordinary differential equation with a given initial condition is introduced. The method is using a numerical integration procedure for an equivalent integral equation and is called in this paper…

Numerical Analysis · Mathematics 2011-09-06 Alexander Lozovskiy

The aim of this work is to give an overview of the recent developments in the area of statistical inference for parabolic stochastic partial differential equations. Significant part of the paper is devoted to the spectral approach, which is…

Probability · Mathematics 2017-12-18 Igor Cialenco

This paper considers sparse linear discriminant analysis of high-dimensional data. In contrast to the existing methods which are based on separate estimation of the precision matrix $\O$ and the difference $\de$ of the mean vectors, we…

Methodology · Statistics 2011-07-19 Tony Cai , Weidong Liu

orthoDr is a package in R that solves dimension reduction problems using orthogonality constrained optimization approach. The package serves as a unified framework for many regression and survival analysis dimension reduction models that…

Computation · Statistics 2019-07-05 Ruoqing Zhu , Jiyang Zhang , Ruilin Zhao , Peng Xu , Wenzhuo Zhou , Xin Zhang

In this paper, we further consider the symmetry-based method for seeking nonlocally related systems for partial differential equations. In particular, we show that the symmetry-based method for partial differential equations is the natural…

Analysis of PDEs · Mathematics 2024-07-15 George W. Bluman , Rafael de la Rosa

The prediction interval is gaining prominence in meta-analysis as it enables the assessment of uncertainties in treatment effects and heterogeneity between studies. However, coverage probabilities of the current standard method for…

Methodology · Statistics 2021-10-18 Kengo Nagashima , Hisashi Noma , Toshi A. Furukawa

Differential equations are commonly used to model dynamical deterministic systems in applications. When statistical parameter estimation is required to calibrate theoretical models to data, classical statistical estimators are often…

Methodology · Statistics 2014-10-29 Nicolas J-B Brunel , Quentin Clairon , Florence d'Alche-Buc

The interpretation of numerical methods, such as finite difference methods for differential equations, as point estimators suggests that formal uncertainty quantification can also be performed in this context. Competing statistical…

Other Statistics · Statistics 2019-09-24 Junyang Wang , Jon Cockayne , Chris J. Oates

Differential algebra approaches to structural identifiability analysis of a dynamic system model in many instances heavily depend upon Ritt's pseudodivision at an early step in analysis. The pseudodivision algorithm is used to find the…

Algebraic Geometry · Mathematics 2012-03-21 Nicolette Meshkat , Chris Anderson , Joseph J. DiStefano

Identifying from observation data the governing differential equations of a physical dynamics is a key challenge in machine learning. Although approaches based on SINDy have shown great promise in this area, they still fail to address a…

Machine Learning · Computer Science 2025-10-22 Fayad Ali Banna , Antoine Caradot , Eduardo Brandao , Jean-Philippe Colombier , Rémi Emonet , Marc Sebban