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Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

Optics · Physics 2021-07-07 Ivan Vishniakou , Johannes D. Seelig

Lensless imaging is an elegant approach to high-resolution microscopy, which is rapidly gaining popularity in applications where imaging optics are problematic. However, current lensless imaging methods require objects to be placed within a…

Multimode fibers (MMFs) show great promise as miniature probes for sensing, imaging and spectroscopy applications. Different parameters of the fibers, such as numerical aperture, refractive index profile and length, have been already…

Rigid endoscopes like graded-index (GRIN) lenses are known tools in biological imaging, but it is conceptually difficult to miniaturize them. In this letter, we demonstrate an ultra-thin rigid endoscope with a diameter of only 125 microns.…

Diffraction-limited imaging through complex scattering media is a long sought after goal with important applications in biomedical research. In recent years, high resolution wavefront-shaping has emerged as a powerful approach to generate a…

Optics · Physics 2014-10-17 Ori Katz , Eran Small , Yefeng Guan , Yaron Silberberg

Observations from ground based telescopes are affected by the presence of the Earth atmosphere, which severely perturbs them. The use of adaptive optics techniques has allowed us to partly beat this limitation. However, image selection or…

Instrumentation and Methods for Astrophysics · Physics 2021-02-17 A. Asensio Ramos , N. Olspert

Raman spectroscopy is a label-free, chemically specific optical technique which provides detailed information about the chemical composition and structure of the excited analyte. Because of this, there is growing research interest in…

We present a robust, fiber based endoscope with a silver direct-laser-written (DLW) structure for radio frequency (RF) emission next to the optical fiber facet. Thereby, we are able to excite and probe a sample, such as nitrogen vacancy…

Instrumentation and Detectors · Physics 2022-10-12 Stefan Dix , Jonas Gutsche , Erik Waller , Georg von Freymann , Artur Widera

We are now moving into an era where multi-object wide-field surveys, which traditionally use single fibres to observe many targets simultaneously, can exploit compact integral field units in place of single fibres. Current multi-object…

Instrumentation and Methods for Astrophysics · Physics 2015-06-18 Julia Bryant , Joss Bland-Hawthorn , Lisa Fogarty , Jon Lawrence , Scott Croom

Optical focusing at depths in tissue is the Holy Grail of biomedical optics that may bring revolutionary advancement to the field. Wavefront shaping is a widely accepted approach to solve this problem, but most implementations thus far have…

Applied Physics · Physics 2019-09-04 Yunqi Luo , Suxia Yan , Huanhao Li , Puxiang Lai , Yuanjin Zheng

Optical tweezers enable non-contact trapping of micro-scale objects using light. Despite their widespread use, it is currently not known how tightly it is possible to three-dimensionally trap micro-particles with a given photon budget.…

Quantum imaging with spatially entangled photons offers advantages such as enhanced spatial resolution, robustness against noise, and counter-intuitive phenomena, while a biphoton spatial aberration generally degrades its performance.…

Quantum Physics · Physics 2025-09-10 Yi Zheng , Zhao-Di Liu , Jian-Shun Tang , Jin-Shi Xu , Chuan-Feng Li , Guang-Can Guo

Adaptive optics enables the deployment of interferometer-based spectroscopy without the need for moving parts necessary for scanning the interferometer arms. Here, we employ a Michelson Interferometer in conjunction with a Spatial Light…

Optics · Physics 2025-12-05 Jesneil Lauren Lewis , Ayan Banerjee

We report two-photon lensless imaging through a novel golden spiral multicore fiber. This unique layout optimizes the sidelobe levels, field of view, cross-talk, group delay and mode density to achieve a sidelobe contrast of atleast 10.9…

Wavefront shaping enables targeted delivery of coherent light into random-scattering media, such as biological tissue, by constructive interference of scattered waves. However, broadband waves have short coherence times, weakening the…

Imaging techniques such as functional near-infrared spectroscopy (fNIRS) and diffuse optical tomography (DOT) achieve deep, non-invasive sensing in turbid media, but they are constrained by the photon budget. Wavefront shaping (WFS) can…

Optics · Physics 2026-04-21 Pablo Jara , Arthur Goetschy , Hui Cao , Alexey Yamilov

Wavefront shaping enables precise control of light propagation through multimode fibers (MMFs), facilitating diffraction-limited focusing for applications such as high-resolution single-fiber imaging and high-power fiber amplifiers. While…

Optics · Physics 2025-11-06 Amna Ammar , Sarp Feykun Şener , Mert Ercan , Hasan Yılmaz

The usage of a GaAsP (gallium arsenide phosphide) photomultiplier for microscopical imaging allows the evaluation of low-light luminescent objects. We designed a setup for collecting a confocal microscopic image signal, which is divided…

Modern extreme adaptive optics (AO) systems achieving diffraction-limited performance open up new possibilities for instrumentation. Especially important for the fields of spectroscopy and interferometry is that it enables the prospect to…

Shack-Hartmann wavefront sensors using wound fibre bundles are desired for multi-object adaptive optical systems to provide large multiplex positioned by Starbugs. The use of the large-sized wound fibre bundle provides the exibility to use…

Instrumentation and Methods for Astrophysics · Physics 2018-04-11 Jessica R. Zheng , Michael Goodwin , Jon Lawrence
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