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Dynamic Contrast Enhanced-Magnetic Resonance Imaging (DCE-MRI) is widely used to complement ultrasound examinations and x-ray mammography during the early detection and diagnosis of breast cancer. However, images generated by various MRI…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Gourav Modanwal , Adithya Vellal , Maciej A. Mazurowski

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in breast cancer screening, tumor assessment, and treatment planning and monitoring. The dynamic changes in contrast in different tissues help to…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Rui Wang , Yuexi Du , John Lewin , R. Todd Constable , Nicha C. Dvornek

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in diagnosis and grading of brain tumor. Although manual DCE biomarker extraction algorithms boost the diagnostic yield of DCE-MRI by providing…

Deep transfer learning using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has shown strong predictive power in characterization of breast lesions. However, pretrained convolutional neural networks (CNNs) require 2D inputs,…

Medical Physics · Physics 2019-11-11 Qiyuan Hu , Heather M. Whitney , Maryellen L. Giger

Purpose: We propose a deep learning-based computer-aided detection (CADe) method to detect breast lesions in ultrafast DCE-MRI sequences. This method uses both the three-dimensional spatial information and temporal information obtained from…

Image and Video Processing · Electrical Eng. & Systems 2021-11-12 Fazael Ayatollahi , Shahriar B. Shokouhi , Ritse M. Mann , Jonas Teuwen

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Purpose: To develop a deep network architecture that would achieve fully automated radiologist-level segmentation of cancers at breast MRI. Materials and Methods: In this retrospective study, 38229 examinations (composed of 64063 individual…

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

Objective: In this work, we perform margin assessment of human breast tissue from optical coherence tomography (OCT) images using deep neural networks (DNNs). This work simulates an intraoperative setting for breast cancer lumpectomy.…

Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in clinical setting, enhancing the…

Numerical Analysis · Mathematics 2020-07-21 Elena Morotti , Elena Loli Piccolomini

Computer-aided detection or decision support systems aim to improve breast cancer screening programs by helping radiologists to evaluate digital mammography (DM) exams. Commonly such methods proceed in two steps: selection of candidate…

Computer Vision and Pattern Recognition · Computer Science 2018-03-09 Timothy de Moor , Alejandro Rodriguez-Ruiz , Albert Gubern Mérida , Ritse Mann , Jonas Teuwen

Breast density estimation is one of the key tasks in recognizing individuals predisposed to breast cancer. It is often challenging because of low contrast and fluctuations in mammograms' fatty tissue background. Most of the time, the breast…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Vikash Gupta , Mutlu Demirer , Robert W. Maxwell , Richard D. White , Barbaros Selnur Erdal

Image synthesis learns a transformation from the intensity features of an input image to yield a different tissue contrast of the output image. This process has been shown to have application in many medical image analysis tasks including…

Computer Vision and Pattern Recognition · Computer Science 2018-12-13 Jacob C. Reinhold , Blake E. Dewey , Aaron Carass , Jerry L. Prince

Radiomics analysis has emerged as a promising approach for extracting quantitative features from medical images to aid in cancer diagnosis and treatment. However, radiomics research currently lacks standardization, and radiomics features…

Accurate molecular subtype classification is essential for personalized breast cancer treatment, yet conventional immunohistochemical analysis relies on invasive biopsies and is prone to sampling bias. Although dynamic contrast-enhanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

Breast cancer is the most common malignant tumor among women and the second cause of cancer-related death. Early diagnosis in clinical practice is crucial for timely treatment and prognosis. Dynamic contrast-enhanced magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zixian Li , Yuming Zhong , Yi Wang

This paper presents a method for virtual contrast enhancement in breast MRI, offering a promising non-invasive alternative to traditional contrast agent-based DCE-MRI acquisition. Using a conditional generative adversarial network, we…

Image and Video Processing · Electrical Eng. & Systems 2025-05-15 Richard Osuala , Smriti Joshi , Apostolia Tsirikoglou , Lidia Garrucho , Walter H. L. Pinaya , Daniel M. Lang , Julia A. Schnabel , Oliver Diaz , Karim Lekadir

Image normalization is a building block in medical image analysis. Conventional approaches are customarily utilized on a per-dataset basis. This strategy, however, prevents the current normalization algorithms from fully exploiting the…

Machine Learning · Computer Science 2020-10-06 Pierre-Luc Delisle , Benoit Anctil-Robitaille , Christian Desrosiers , Herve Lombaert
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