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When the cost of misclassifying a sample is high, it is useful to have an accurate estimate of uncertainty in the prediction for that sample. There are also multiple types of uncertainty which are best estimated in different ways, for…

Machine Learning · Computer Science 2019-03-18 Richard Harang , Ethan M. Rudd

Despite AI's impressive achievements, including recent advances in generative and large language models, there remains a significant gap in the ability of AI systems to handle uncertainty and generalize beyond their training data. AI models…

Artificial Intelligence · Computer Science 2025-06-30 Shireen Kudukkil Manchingal , Andrew Bradley , Julian F. P. Kooij , Keivan Shariatmadar , Neil Yorke-Smith , Fabio Cuzzolin

Deep neural networks are powerful tools to detect hidden patterns in data and leverage them to make predictions, but they are not designed to understand uncertainty and estimate reliable probabilities. In particular, they tend to be…

Machine Learning · Statistics 2022-11-10 Bat-Sheva Einbinder , Yaniv Romano , Matteo Sesia , Yanfei Zhou

Uncertainty quantification in automated image analysis is highly desired in many applications. Typically, machine learning models in classification or segmentation are only developed to provide binary answers; however, quantifying the…

Artificial neural networks will always make a prediction, even when completely uncertain and regardless of the consequences. This obliviousness of uncertainty is a major obstacle towards their adoption in practice. Techniques exist,…

Machine Learning · Computer Science 2021-05-13 Hans Weytjens , Jochen De Weerdt

Artificial Intelligence (AI) holds the potential to dramatically improve patient care. However, it is not infallible, necessitating human-AI-collaboration to ensure safe implementation. One aspect of AI safety is the models' ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Anna M. Wundram , Christian F. Baumgartner

In machine learning, accurately predicting the probability that a specific input is correct is crucial for risk management. This process, known as uncertainty (or confidence) estimation, is particularly important in mission-critical…

Machine Learning · Computer Science 2023-01-12 Gabriella Chouraqui , Liron Cohen , Gil Einziger , Liel Leman

Proper quantification of predictive uncertainty is essential for the use of machine learning in safety-critical applications. Various uncertainty measures have been proposed for this purpose, typically claiming superiority over other…

Machine Learning · Computer Science 2025-12-16 Paul Hofman , Yusuf Sale , Eyke Hüllermeier

Deep learning models have demonstrated remarkable success in various fields, including seismology. However, one major challenge in deep learning is the presence of mislabeled examples. Additionally, accurately estimating model uncertainty…

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

Deep learning models are now used in many different industries, while in certain domains safety is not a critical issue in the medical field it is a huge concern. Not only, we want the models to generalize well but we also want to know the…

Machine Learning · Computer Science 2019-07-08 Jae Duk Seo

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Ensemble learning is widely applied in Machine Learning (ML) to improve model performance and to mitigate decision risks. In this approach, predictions from a diverse set of learners are combined to obtain a joint decision. Recently,…

Machine Learning · Computer Science 2020-07-14 Yingshui Tan , Baihong Jin , Xiangyu Yue , Yuxin Chen , Alberto Sangiovanni Vincentelli

Modern neural networks (NNs) often achieve high predictive accuracy but are poorly calibrated, producing overconfident predictions even when wrong. This miscalibration poses serious challenges in applications where reliable uncertainty…

Machine Learning · Computer Science 2025-09-12 Pedro Mendes , Paolo Romano , David Garlan

As interpretability has been pointed out as the obstacle to the adoption of Deep Neural Networks (DNNs), there is an increasing interest in solving a transparency issue to guarantee the impressive performance. In this paper, we demonstrate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Woo-Jeoung Nam , Seong-Whan Lee

Deep learning models frequently make incorrect predictions with high confidence when presented with test examples that are not well represented in their training dataset. We propose a novel and straightforward approach to estimate…

Machine Learning · Computer Science 2019-10-04 Tiago Ramalho , Miguel Miranda

Uncertainty estimation methods are expected to improve the understanding and quality of computer-assisted methods used in medical applications (e.g., neurosurgical interventions, radiotherapy planning), where automated medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Alain Jungo , Raphael Meier , Ekin Ermis , Marcela Blatti-Moreno , Evelyn Herrmann , Roland Wiest , Mauricio Reyes

There are two major types of uncertainty one can model. Aleatoric uncertainty captures noise inherent in the observations. On the other hand, epistemic uncertainty accounts for uncertainty in the model -- uncertainty which can be explained…

Computer Vision and Pattern Recognition · Computer Science 2017-10-06 Alex Kendall , Yarin Gal

Effective human-machine collaboration requires machine learning models to externalize uncertainty, so users can reflect and intervene when necessary. For language models, these representations of uncertainty may be impacted by sycophancy…

Computation and Language · Computer Science 2024-10-22 Anthony Sicilia , Mert Inan , Malihe Alikhani

As machine learning models are increasingly employed to assist human decision-makers, it becomes critical to communicate the uncertainty associated with these model predictions. However, the majority of work on uncertainty has focused on…

Computer Vision and Pattern Recognition · Computer Science 2021-07-29 Daniel D'souza , Zach Nussbaum , Chirag Agarwal , Sara Hooker
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