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Drug name recognition (DNR) is an essential step in the Pharmacovigilance (PV) pipeline. DNR aims to find drug name mentions in unstructured biomedical texts and classify them into predefined categories. State-of-the-art DNR approaches…

Computation and Language · Computer Science 2016-09-27 Raghavendra Chalapathy , Ehsan Zare Borzeshi , Massimo Piccardi

Statistical Relational Learning (SRL) models have attracted significant attention due to their ability to model complex data while handling uncertainty. However, most of these models have been limited to discrete domains due to their…

Machine Learning · Computer Science 2021-10-20 Yuqiao Chen , Sriraam Natarajan , Nicholas Ruozzi

In recent years, large amounts of electronic health records (EHRs) concerning chronic diseases have been collected to facilitate medical diagnosis. Modeling the dynamic properties of EHRs related to chronic diseases can be efficiently done…

Machine Learning · Computer Science 2025-02-18 Di Wang , Yao Wang , Shao-Bo Lin

Reinforcement learning (RL) has garnered increasing recognition for its potential to optimise dynamic treatment regimes (DTRs) in personalised medicine, particularly for drug dosage prescriptions and medication recommendations. However, a…

Machine Learning · Computer Science 2024-05-30 Zhiyao Luo , Mingcheng Zhu , Fenglin Liu , Jiali Li , Yangchen Pan , Jiandong Zhou , Tingting Zhu

A recurrent neural network (RNN) is a universal approximator of dynamical systems, whose performance often depends on sensitive hyperparameters. Tuning of such hyperparameters may be difficult and, typically, based on a trial-and-error…

Neural and Evolutionary Computing · Computer Science 2017-02-22 Filippo Maria Bianchi , Lorenzo Livi , Cesare Alippi , Robert Jenssen

Countless learning tasks require dealing with sequential data. Image captioning, speech synthesis, and music generation all require that a model produce outputs that are sequences. In other domains, such as time series prediction, video…

Machine Learning · Computer Science 2015-10-20 Zachary C. Lipton , John Berkowitz , Charles Elkan

Real-world decision-making tasks are usually partially observable Markov decision processes (POMDPs), where the state is not fully observable. Recent progress has demonstrated that recurrent reinforcement learning (RL), which consists of a…

Machine Learning · Computer Science 2024-05-27 Fan-Ming Luo , Zuolin Tu , Zefang Huang , Yang Yu

Deep reinforcement learning (deep RL) has been successful in learning sophisticated behaviors automatically; however, the learning process requires a huge number of trials. In contrast, animals can learn new tasks in just a few trials,…

Artificial Intelligence · Computer Science 2016-11-11 Yan Duan , John Schulman , Xi Chen , Peter L. Bartlett , Ilya Sutskever , Pieter Abbeel

Reinforcement learning (RL) algorithms usually require a substantial amount of interaction data and perform well only for specific tasks in a fixed environment. In some scenarios such as healthcare, however, usually only few records are…

Machine Learning · Computer Science 2020-12-17 Chaochao Lu , Biwei Huang , Ke Wang , José Miguel Hernández-Lobato , Kun Zhang , Bernhard Schölkopf

The rapid increase in the percentage of chronic disease patients along with the recent pandemic pose immediate threats on healthcare expenditure and elevate causes of death. This calls for transforming healthcare systems away from…

Machine Learning · Computer Science 2021-08-10 Alaa Awad Abdellatif , Naram Mhaisen , Zina Chkirbene , Amr Mohamed , Aiman Erbad , Mohsen Guizani

Randomized experiments (a.k.a. A/B tests) are a powerful tool for estimating treatment effects, to inform decisions making in business, healthcare and other applications. In many problems, the treatment has a lasting effect that evolves…

Machine Learning · Computer Science 2022-10-17 Ziyang Tang , Yiheng Duan , Stephanie Zhang , Lihong Li

Reinforcement learning (RL) is a goal-oriented learning solution that has proven to be successful for Neural Architecture Search (NAS) on the CIFAR and ImageNet datasets. However, a limitation of this approach is its high computational…

Neural and Evolutionary Computing · Computer Science 2019-12-04 J. Gomez Robles , J. Vanschoren

Recent advances in medical large language models have explored Test-Time Reinforcement Learning (TTRL) to enhance reasoning. However, standard TTRL often relies on majority voting (MV) as a heuristic supervision signal, which can be…

Machine Learning · Computer Science 2026-03-11 Kailong Fan , Anqi Pu , Yichen Wu , Wanhua Li , Yicong Li , Hanspeter Pfister , Huafeng Liu , Xiang Li , Quanzheng Li , Ning Guo

This paper adds to the growing literature of reinforcement learning (RL) for healthcare by proposing a novel paradigm: augmenting any predictor with Rule-based RL Layer (RRLL) that corrects the model's physiologically impossible…

Machine Learning · Computer Science 2025-02-03 Lingwei Zhu , Zheng Chen , Yukie Nagai , Jimeng Sun

Reinforcement Learning (RL) has achieved significant success in application domains such as robotics, games and health care. However, training RL agents is very time consuming. Current implementations exhibit poor performance due to…

Machine Learning · Computer Science 2021-12-24 Chi Zhang , Sanmukh Rao Kuppannagari , Viktor K Prasanna

Spiking Neural Networks (SNNs) have become an essential paradigm in neuroscience and artificial intelligence, providing brain-inspired computation. Recent advances in literature have studied the network representations of deep neural…

Neural and Evolutionary Computing · Computer Science 2024-03-20 Biswadeep Chakraborty , Saibal Mukhopadhyay

Reinforcement Learning (RL) has emerged as a powerful paradigm for training LLM-based agents, yet remains limited by low sample efficiency, stemming not only from sparse outcome feedback but also from the agent's inability to leverage prior…

Machine Learning · Computer Science 2026-03-19 Dilxat Muhtar , Jiashun Liu , Wei Gao , Weixun Wang , Shaopan Xiong , Ju Huang , Siran Yang , Wenbo Su , Jiamang Wang , Ling Pan , Bo Zheng

Strategic recommendations (SR) refer to the problem where an intelligent agent observes the sequential behaviors and activities of users and decides when and how to interact with them to optimize some long-term objectives, both for the user…

Machine Learning · Computer Science 2020-09-17 Georgios Theocharous , Yash Chandak , Philip S. Thomas , Frits de Nijs

Objective: Anemia is a frequent comorbidity in hemodialysis patients that can be successfully treated by administering erythropoiesis-stimulating agents (ESAs). ESAs dosing is currently based on clinical protocols that often do not account…

Reinforcement learning (RL) has a rich history in neuroscience, from early work on dopamine as a reward prediction error signal (Schultz et al., 1997) to recent work proposing that the brain could implement a form of 'distributional…

Neurons and Cognition · Quantitative Biology 2024-12-19 Kristopher T. Jensen
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