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One of the most important challenges in mathematical neuroscience is to properly illustrate the stochastic nature of neurons. Among different approaches, the noisy leaky integrate-and-fire and the escape rate models are probably the most…

Analysis of PDEs · Mathematics 2017-02-07 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

The steady-state firing rate and firing-rate response of the leaky and exponential integrate-and-fire models receiving synaptic shot noise with excitatory and inhibitory reversal potentials is examined. For the particular case where the…

Neurons and Cognition · Quantitative Biology 2024-03-13 Magnus J E Richardson

Stochastic integrate-and-fire (IF) neuron models have found widespread applications in computational neuroscience. Here we present results on the white-noise-driven perfect, leaky, and quadratic IF models, focusing on the spectral…

Neurons and Cognition · Quantitative Biology 2015-05-14 Rafael D. Vilela , Benjamin Lindner

Spiking Neural Networks (SNNs) are being explored to emulate the astounding capabilities of human brain that can learn and compute functions robustly and efficiently with noisy spiking activities. A variety of spiking neuron models have…

Neural and Evolutionary Computing · Computer Science 2020-06-17 Sayeed Shafayet Chowdhury , Chankyu Lee , Kaushik Roy

In a generic neuron model, we present the linear response theory for the firing rate in response to both time dependent input currents and noise amplitudes. In both cases the signal transmission is strongly attenuated for frequencies above…

Biological Physics · Physics 2007-05-23 Bjoern Naundorf , Theo Geisel , Fred Wolf

Recently, the so-called next-generation neural mass models have received a lot of attention of the researchers in the field of mathematical neuroscience. The ability of these models to account for the degree of synchrony in neural…

Chaotic Dynamics · Physics 2022-05-05 Vladimir Klinshov , Sergey Kirillov

This work reports a transfer function-based approach to characterizing the operation of single neuronal cells in terms of the instantaneous frequency of the input and output signals. We adopt the leaky integrate-and-fire model. The transfer…

Neurons and Cognition · Quantitative Biology 2019-10-23 Felipe L. Gewers , Luciano da F. Costa

Providing an analytical treatment to the stochastic feature of neurons' dynamics is one of the current biggest challenges in mathematical biology. The noisy leaky integrate-and-fire model and its associated Fokker-Planck equation are…

Neurons and Cognition · Quantitative Biology 2015-12-14 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

Artificial neural networks (ANNs) have been extensively used for the description of problems arising from biological systems and for constructing neuromorphic computing models. The third generation of ANNs, namely, spiking neural networks…

Neurons and Cognition · Quantitative Biology 2022-06-18 Thi Kim Thoa Thieu , Roderick Melnik

We use mean field theory to study the response properties of a simple randomly-connected model cortical network of leaky integrate-and-fire neurons with balanced excitation and inhibition. The formulation permits arbitrary temporal…

Disordered Systems and Neural Networks · Physics 2007-05-23 John Hertz , Barry Richmond , Kristian Nilsen

The leaky integrate and fire (LIF) neuron represents standard neuronal model used for numerical simulations. The leakage is implemented in the model as exponential decay of trans-membrane voltage towards its resting value. This makes…

Neurons and Cognition · Quantitative Biology 2015-05-26 A. K. Vidybida

Using an exactly solvable cortical model of a neuronal network, we show that, by increasing the intensity of shot noise (flow of random spikes bombarding neurons), the network undergoes first- and second-order non-equilibrium phase…

Biological Physics · Physics 2015-08-26 K. -E. Lee , M. A. Lopes , A. V. Goltsev

The computation performed by a neuron can be formulated as a combination of dimensional reduction in stimulus space and the nonlinearity inherent in a spiking output. White noise stimulus and reverse correlation (the spike-triggered average…

Biological Physics · Physics 2007-05-23 Blaise Aguera y Arcas , Adrienne Fairhall

The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the…

Neurons and Cognition · Quantitative Biology 2024-01-09 Afifurrahman , Mohd Hafiz Mohd , Farah Aini Abdullah

Neurons in the nervous system are submitted to distinct sources of noise, such as ionic-channel and synaptic noise, which introduces variability in their responses to repeated presentations of identical stimuli. This motivates the use of…

Interest in understanding the interplay between noise and the response of a non-linear device cuts across disciplinary boundaries. It is as relevant for unmasking the dynamics of neurons in noisy environments as it is for designing reliable…

Biological Physics · Physics 2011-05-16 Cameron Sobie , Arif Babul , Rogerio de Sousa

A population of firing neurons is expected to carry not only mean firing rate but also its fluctuation and synchrony among neurons. In order to examine this possibility, we have studied responses of neuronal ensembles to three kinds of…

Disordered Systems and Neural Networks · Physics 2008-02-18 Hiode Hasegawa

While recent advances in next-generation neural mass models provide exact descriptions of densely coupled neural populations in the thermodynamic limit, populations in vivo remain strictly finite in size. Finite-size effects introduce…

Chaotic Dynamics · Physics 2026-05-19 S. Yu. Kirillov , O. A. Goryunov , J. Zhu , V. V. Klinshov

Spiking neural networks (SNNs), inspired by the neural circuits of the brain, are promising in achieving high computational efficiency with biological fidelity. Nevertheless, it is quite difficult to optimize SNNs because the functional…

Neural and Evolutionary Computing · Computer Science 2025-01-28 Huifeng Yin , Hanle Zheng , Jiayi Mao , Siyuan Ding , Xing Liu , Mingkun Xu , Yifan Hu , Jing Pei , Lei Deng

Neurons in the brain continuously process the barrage of sensory inputs they receive from the environment. A wide array of experimental work has shown that the collective activity of neural populations encodes and processes this constant…

Neurons and Cognition · Quantitative Biology 2025-10-30 Siddharth Paliwal , Gabriel Koch Ocker , Braden A. W. Brinkman
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