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In this paper, we seek a clinically-relevant latent code for representing the spectrum of macular disease. Towards this end, we construct retina-VAE, a variational autoencoder-based model that accepts a patient profile vector (pVec) as…

Image and Video Processing · Electrical Eng. & Systems 2019-07-12 Stephen G. Odaibo

Pathologists have a rich vocabulary with which they can describe all the nuances of cellular morphology. In their world, there is a natural pairing of images and words. Recent advances demonstrate that machine learning models can now be…

Machine Learning · Computer Science 2022-07-14 Simon M. Thomas , James G. Lefevre , Glenn Baxter , Nicholas A. Hamilton

The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns…

Quantitative Methods · Quantitative Biology 2017-08-25 Paolo Inglese , James L. Alexander , Anna Mroz , Zoltan Takats , Robert Glen

Cancer is a heterogeneous disease with diverse molecular etiologies and outcomes. The Cancer Genome Atlas (TCGA) has released a large compendium of over 10,000 tumors with RNA-seq gene expression measurements. Gene expression captures the…

Genomics · Quantitative Biology 2017-11-15 Gregory P. Way , Casey S. Greene

Detecting various types of stresses (nutritional, water, nitrogen, etc.) in agricultural fields is critical for farmers to ensure maximum productivity. However, stresses show up in different shapes and sizes across different crop types and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Sambal Shikhar , Anupam Sobti

Unsupervised anomaly detection models which are trained solely by healthy data, have gained importance in the recent years, as the annotation of medical data is a tedious task. Autoencoders and generative adversarial networks are the…

Computer Vision and Pattern Recognition · Computer Science 2022-12-12 Marc Dietrichstein , David Major , Martin Trapp , Maria Wimmer , Dimitrios Lenis , Philip Winter , Astrid Berg , Theresa Neubauer , Katja Bühler

In the recent times, autoencoders, besides being used for compression, have been proven quite useful even for regenerating similar images or help in image denoising. They have also been explored for anomaly detection in a few cases.…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Shruti Mittal , Dattaraj Rao

Deep generative learning cannot only be used for generating new data with statistical characteristics derived from input data but also for anomaly detection, by separating nominal and anomalous instances based on their reconstruction…

In this paper, we studied extensively on different deep learning based methods to detect melanoma and skin lesion cancers. Melanoma, a form of malignant skin cancer is very threatening to health. Proper diagnosis of melanoma at an earlier…

Computer Vision and Pattern Recognition · Computer Science 2019-01-31 Md Ashraful Alam Milton

In the contemporary digital landscape, the continuous generation of extensive streaming data across diverse domains has become pervasive. Yet, a significant portion of this data remains unlabeled, posing a challenge in identifying…

Computational Engineering, Finance, and Science · Computer Science 2025-08-25 Jin Li , Kleanthis Malialis , Christos G. Panayiotou , Marios M. Polycarpou

In this tutorial, we explore Variational Autoencoders (VAEs), an essential framework for unsupervised learning, particularly suited for high-dimensional datasets such as neuroimaging. By integrating deep learning with Bayesian inference,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz Sáez

Variational autoencoders (VAEs) are influential generative models with rich representation capabilities from the deep neural network architecture and Bayesian method. However, VAE models have a weakness that assign a higher likelihood to…

Machine Learning · Computer Science 2021-11-02 Xuming Ran , Mingkun Xu , Lingrui Mei , Qi Xu , Quanying Liu

Detecting out-of-distribution (OOD) samples in medical imaging plays an important role for downstream medical diagnosis. However, existing OOD detectors are demonstrated on natural images composed of inter-classes and have difficulty…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Xiaoyuan Guo , Judy Wawira Gichoya , Saptarshi Purkayastha , Imon Banerjee

Although variational autoencoders (VAEs) represent a widely influential deep generative model, many aspects of the underlying energy function remain poorly understood. In particular, it is commonly believed that Gaussian encoder/decoder…

Machine Learning · Computer Science 2019-10-31 Bin Dai , David Wipf

In this paper, a deep neural network based ensemble method is experimented for automatic identification of skin disease from dermoscopic images. The developed algorithm is applied on the task3 of the ISIC 2018 challenge dataset (Skin Lesion…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Anabik Pal , Sounak Ray , Utpal Garain

Deep learning has made significant strides in medical imaging, leveraging the use of large datasets to improve diagnostics and prognostics. However, large datasets often come with inherent errors through subject selection and acquisition.…

Melanoma, one of the deadliest types of skin cancer, accounts for thousands of fatalities globally. The bluish, blue-whitish, or blue-white veil (BWV) is a critical feature for diagnosing melanoma, yet research into detecting BWV in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 M. A. Rasel , Sameem Abdul Kareem , Zhenli Kwan , Shin Shen Yong , Unaizah Obaidellah

We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational…

Machine Learning · Statistics 2017-07-07 Ladislav Rampasek , Daniel Hidru , Petr Smirnov , Benjamin Haibe-Kains , Anna Goldenberg

Skin lesions known as naevi exhibit diverse characteristics such as size, shape, and colouration. The concept of an "Ugly Duckling Naevus" comes into play when monitoring for melanoma, referring to a lesion with distinctive features that…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Fatima Al Zegair , Nathasha Naranpanawa , Brigid Betz-Stablein , Monika Janda , H. Peter Soyer , Shekhar S. Chandra

In this paper, we explore the use of a variational autoencoder (VAE), a deep generative model, to compress and generate images of dark matter density fields from $\Lambda$CDM like cosmological simulations. The VAE learns a compact,…

Cosmology and Nongalactic Astrophysics · Physics 2025-07-25 Jazhiel Chacón-Lavanderos , Isidro Gómez-Vargas , Ricardo Menchaca-Mendez , J. Alberto Vázquez
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