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Volumetric lesion segmentation via medical imaging is a powerful means to precisely assess multiple time-point lesion/tumor changes. Because manual 3D segmentation is prohibitively time consuming and requires radiological experience,…

Computer Vision and Pattern Recognition · Computer Science 2018-01-29 Jinzheng Cai , Youbao Tang , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

Lesion segmentation on computed tomography (CT) scans is an important step for precisely monitoring changes in lesion/tumor growth. This task, however, is very challenging since manual segmentation is prohibitively time-consuming,…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Vatsal Agarwal , Youbao Tang , Jing Xiao , Ronald M. Summers

Lesion segmentation in medical imaging serves as an effective tool for assessing tumor sizes and monitoring changes in growth. However, not only is manual lesion segmentation time-consuming, but it is also expensive and requires expert…

Computer Vision and Pattern Recognition · Computer Science 2020-01-28 Vatsal Agarwal , Youbao Tang , Jing Xiao , Ronald M. Summers

As an essential indicator for cancer progression and treatment response, tumor size is often measured following the response evaluation criteria in solid tumors (RECIST) guideline in CT slices. By marking each lesion with its longest axis…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Lianyu Zhou , Dong Wei , Donghuan Lu , Wei Xue , Liansheng Wang , Yefeng Zheng

Volumetric segmentation of lesions on CT scans is important for many types of analysis, including lesion growth kinetic modeling in clinical trials and machine learning of radiomic features. Manual segmentation is laborious, and impractical…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Bo Zhou , Randolph Crawford , Belma Dogdas , Gregory Goldmacher , Antong Chen

Response evaluation criteria in solid tumors (RECIST) is the standard measurement for tumor extent to evaluate treatment responses in cancer patients. As such, RECIST annotations must be accurate. However, RECIST annotations manually…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Youbao Tang , Adam P. Harrison , Mohammadhadi Bagheri , Jing Xiao , Ronald M. Summers

Universal lesion detection in computed tomography (CT) images is an important yet challenging task due to the large variations in lesion type, size, shape, and appearance. Considering that data in clinical routine (such as the DeepLesion…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Cong Xie , Shilei Cao , Dong Wei , Hongyu Zhou , Kai Ma , Xianli Zhang , Buyue Qian , Liansheng Wang , Yefeng Zheng

Accurate, automated lesion detection in Computed Tomography (CT) is an important yet challenging task due to the large variation of lesion types, sizes, locations and appearances. Recent work on CT lesion detection employs two-stage region…

Image and Video Processing · Electrical Eng. & Systems 2019-06-07 Martin Zlocha , Qi Dou , Ben Glocker

Measuring lesion size is an important step to assess tumor growth and monitor disease progression and therapy response in oncology image analysis. Although it is tedious and highly time-consuming, radiologists have to work on this task by…

Image and Video Processing · Electrical Eng. & Systems 2021-05-06 Youbao Tang , Ke Yan , Jinzheng Cai , Lingyun Huang , Guotong Xie , Jing Xiao , Jingjing Lu , Gigin Lin , Le Lu

In this paper, we demonstrate the feasibility and performance of deep residual neural networks for volumetric segmentation of irreversibly damaged brain tissue lesions on T1-weighted MRI scans for chronic stroke patients. A total of 239…

Image and Video Processing · Electrical Eng. & Systems 2019-11-27 Naofumi Tomita , Steven Jiang , Matthew E. Maeder , Saeed Hassanpour

Automatically measuring lesion/tumor size with RECIST (Response Evaluation Criteria In Solid Tumors) diameters and segmentation is important for computer-aided diagnosis. Although it has been studied in recent years, there is still space to…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Youbao Tang , Ning Zhang , Yirui Wang , Shenghua He , Mei Han , Jing Xiao , Ruei-Sung Lin

Finding automatically multiple lesions in large images is a common problem in medical image analysis. Solving this problem can be challenging if, during optimization, the automated method cannot access information about the location of the…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Florian Dubost , Hieab Adams , Pinar Yilmaz , Gerda Bortsova , Gijs van Tulder , M. Arfan Ikram , Wiro Niessen , Meike Vernooij , Marleen de Bruijne

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

Accurate segmentation of Optical Coherence Tomography (OCT) images is crucial for diagnosing and monitoring retinal diseases. However, the labor-intensive nature of pixel-level annotation limits the scalability of supervised learning for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Jiaqi Yang , Nitish Mehta , Xiaoling Hu , Chao Chen , Chia-Ling Tsai

Prostate specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) imaging provides a tremendously exciting frontier in visualization of prostate cancer (PCa) metastatic lesions. However, accurate…

Medical Physics · Physics 2024-12-05 Amirhosein Toosi , Sara Harsini , François Bénard , Carlos Uribe , Arman Rahmim

Semantic segmentation neural networks require pixel-level annotations in large quantities to achieve a good performance. In the medical domain, such annotations are expensive, because they are time-consuming and require expert knowledge.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Grzegorz Chlebus , Andrea Schenk , Horst K. Hahn , Bram van Ginneken , Hans Meine

In this paper, we develop a new weakly-supervised learning algorithm to learn to segment cancerous regions in histopathology images. Our work is under a multiple instance learning framework (MIL) with a new formulation, deep weak…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Zhipeng Jia , Xingyi Huang , Eric I-Chao Chang , Yan Xu

Weakly supervised segmentation is an important problem in medical image analysis due to the high cost of pixelwise annotation. Prior methods, while often focusing on weak labels of 2D images, exploit few structural cues of volumetric…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Qian He , Shuailin Li , Xuming He

Accurately segmenting a variety of clinically significant lesions from whole body computed tomography (CT) scans is a critical task on precision oncology imaging, denoted as universal lesion segmentation (ULS). Manual annotation is the…

Image and Video Processing · Electrical Eng. & Systems 2021-05-05 Youbao Tang , Jinzheng Cai , Ke Yan , Lingyun Huang , Guotong Xie , Jing Xiao , Jingjing Lu , Gigin Lin , Le Lu

In clinical trials, one of the radiologists' routine work is to measure tumor sizes on medical images using the RECIST criteria (Response Evaluation Criteria In Solid Tumors). However, manual measurement is tedious and subject to…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Youbao Tang , Ke Yan , Jing Xiao , Ranold M. Summers
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