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When inhibitory neurons constitute about 40% of neurons they could have an important antinociceptive role, as they would easily regulate the level of activity of other neurons. We consider a simple network of cortical spiking neurons with…

Neurons and Cognition · Quantitative Biology 2014-01-28 Fernando Montani , Emilia B. Deleglise , Osvaldo A. Rosso

Neurostimulation using weak electric fields has generated excitement in recent years due to its potential as a medical intervention. However, study of this stimulation modality has been hampered by inconsistent results and large variability…

Neurons and Cognition · Quantitative Biology 2020-01-29 Frances Hutchings , Christopher Thornton , Chencheng Zhang , Yujiang Wang , Marcus Kaiser

Mesoscopic models of finite-size neuronal populations are crucial to understand the dynamics of neural networks in the brain, especially their fluctuations and response to stimuli. However, current theories to derive such models are based…

Neurons and Cognition · Quantitative Biology 2026-01-26 Nils E. Greven , Jonas Ranft , Tilo Schwalger

Single unit recordings in the human medial temporal lobe (MTL) have revealed a population of cells with conceptually based, highly selective activity, indicating the presence of a sparse neural code. Building off previous work by the author…

Neurons and Cognition · Quantitative Biology 2015-08-19 Andrew Magyar

We observe and study a self-organized phenomenon whereby the activity in a network of spiking neurons spontaneously terminates. We consider different types of populations, consisting of bistable model neurons connected electrically by gap…

Disordered Systems and Neural Networks · Physics 2018-11-22 Muhammet Uzuntarla , Joaquin J. Torres , Ali Çalım , Ernest Barreto

Understanding how the complex connectivity structure of the brain shapes its information-processing capabilities is a long-standing question. By focusing on a paradigmatic architecture, we study how the neural activity of excitatory and…

Statistical Mechanics · Physics 2024-10-18 Giacomo Barzon , Daniel Maria Busiello , Giorgio Nicoletti

A rigorous bridge between spiking-level and macroscopic quantities is an on-going and well-developed story for asynchronously firing neurons, but focus has shifted to include neural populations exhibiting varying synchronous dynamics.…

Neurons and Cognition · Quantitative Biology 2018-08-16 Youngmin Park , G. Bard Ermentrout

To study information processing in the brain, neuroscientists manipulate experimental stimuli while recording participant brain activity. They can then use encoding models to find out which brain "zone" (e.g. which region of interest,…

Neurons and Cognition · Quantitative Biology 2022-02-22 Mariya Toneva , Jennifer Williams , Anand Bollu , Christoph Dann , Leila Wehbe

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

We study bifurcations in networks of integrate-and-fire neurons with stochastic spike emission, focusing on the effects of the spatial and temporal structure of the synaptic interactions. Using a deterministic mean-field approximation of…

Neurons and Cognition · Quantitative Biology 2026-05-19 Lauren Forbes , Jared Grossman , Montie Avery , Ryan Goh , Gabriel Koch Ocker

For modeling complex synaptic connectivity, we consider the Watts-Strogatz small-world network which interpolates between regular lattice and random network via rewiring, and investigate the effect of small-world connectivity on emergence…

Neurons and Cognition · Quantitative Biology 2014-07-11 Sang-Yoon Kim , Woochang Lim

Cortical neurons are characterized by irregular firing and a broad distribution of rates. The balanced state model explains these observations with a cancellation of mean excitatory and inhibitory currents, which makes fluctuations drive…

Neurons and Cognition · Quantitative Biology 2020-10-15 Alessandro Sanzeni , Mark H Histed , Nicolas Brunel

Neural networks, specifically deep convolutional neural networks, have achieved unprecedented performance in various computer vision tasks, but the rationale for the computations and structures of successful neural networks is not fully…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Joshua Bowren

A neuron transforms its input into output spikes, and this transformation is the basic unit of computation in the nervous system. The spiking response of the neuron to a complex, time-varying input can be predicted from the detailed…

Neurons and Cognition · Quantitative Biology 2011-12-19 Michael Famulare , Adrienne Fairhall

Foundation models have shown remarkable success in fitting biological visual systems; however, their black-box nature inherently limits their utility for understanding brain function. Here, we peek inside a SOTA foundation model of neural…

Neurons and Cognition · Quantitative Biology 2026-01-30 Johannes Bertram , Luciano Dyballa , Anderson Keller , Savik Kinger , Steven W. Zucker

From the action potentials of neurons and cardiac cells to the amplification of calcium signals in oocytes, excitability is a hallmark of many biological signalling processes. In recent years, excitability in single cells has been related…

Dynamical Systems · Mathematics 2023-01-11 Daniele Avitabile , Mathieu Desroches , G. Bard Ermentrout

A single axon can generate branches connecting with plenty synaptic targets. Process of branching is very important for making connections in central nervous system. The interstitial branching along primary axon shaft occurs during nervous…

Neurons and Cognition · Quantitative Biology 2013-04-25 Y. Suleymanov , F. Gafarov , N. Khusnutdinov

Exciton dissociation via the excitonic Mott transition (EMT) governs the high-density optical response of semiconductors and sets fundamental limits for optoelectronic devices. The EMT is conventionally linked to the onset of population…

Oscillations are omnipresent in neural population signals, like multi-unit recordings, EEG/MEG, and the local field potential. They have been linked to the population firing rate of neurons, with individual neurons firing in a…

Neurons and Cognition · Quantitative Biology 2017-02-08 Hannah Bos , Markus Diesmann , Moritz Helias

Repeating spatiotemporal spike patterns exist and carry information. Here we investigated how a single spiking neuron can optimally respond to one given pattern (localist coding), or to either one of several patterns (distributed coding,…

Neural and Evolutionary Computing · Computer Science 2018-09-24 Timothée Masquelier , Saeed Reza Kheradpisheh