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Deep learning models have gained remarkable performance on a variety of image classification tasks. However, many models suffer from limited performance in clinical or medical settings when data are imbalanced. To address this challenge, we…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Margarita L. Zuley , Shandong Wu

Deep learning (DL) models have achieved paradigm-changing performance in many fields with high dimensional data, such as images, audio, and text. However, the black-box nature of deep neural networks is a barrier not just to adoption in…

Machine Learning · Computer Science 2020-02-25 Parmita Mehta , Stephen Portillo , Magdalena Balazinska , Andrew Connolly

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Background: Identification of the interactions and regulatory relations between biomolecules play pivotal roles in understanding complex biological systems and the mechanisms underlying diverse biological functions. However, the collection…

Computation and Language · Computer Science 2025-04-24 Gilchan Park , Byung-Jun Yoon , Xihaier Luo , Vanessa López-Marrero , Shinjae Yoo , Shantenu Jha

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes…

Document-level relation extraction aims at inferring structured human knowledge from textual documents. State-of-the-art methods for this task use pre-trained language models (LMs) via fine-tuning, yet fine-tuning is computationally…

Computation and Language · Computer Science 2024-10-03 Yilmazcan Ozyurt , Stefan Feuerriegel , Ce Zhang

Deep learning approaches exhibit promising performances on various text tasks. However, they are still struggling on medical text classification since samples are often extremely imbalanced and scarce. Different from existing mainstream…

Computation and Language · Computer Science 2023-11-29 Jiahuan Yan , Haojun Gao , Zhang Kai , Weize Liu , Danny Chen , Jian Wu , Jintai Chen

Inclusion of high throughput technologies in the field of biology has generated massive amounts of biological data in the recent years. Now, transforming these huge volumes of data into knowledge is the primary challenge in computational…

Machine Learning · Computer Science 2021-12-06 Dibyendu Ghosh , Srija Chakraborty , Hariprasad Kodamana , Supriya Chakraborty

In the real world, medical datasets often exhibit a long-tailed data distribution (i.e., a few classes occupy the majority of the data, while most classes have only a limited number of samples), which results in a challenging long-tailed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-22 Lie Ju , Zhen Yu , Lin Wang , Xin Zhao , Xin Wang , Paul Bonnington , Zongyuan Ge

Deep learning methods capable of handling relational data have proliferated over the last years. In contrast to traditional relational learning methods that leverage first-order logic for representing such data, these deep learning methods…

Machine Learning · Computer Science 2020-03-25 Sebastijan Dumancic , Tias Guns , Wannes Meert , Hendrik Blockeel

Network biology has been successfully used to help reveal complex mechanisms of disease, especially cancer. On the other hand, network biology requires in-depth knowledge to construct disease-specific networks, but our current knowledge is…

Computer Vision and Pattern Recognition · Computer Science 2018-06-18 Sungmin Rhee , Seokjun Seo , Sun Kim

The extraction of interactions between chemicals and proteins from several biomedical articles is important in many fields of biomedical research such as drug development and prediction of drug side effects. Several natural language…

Computation and Language · Computer Science 2020-11-05 Dongha Choi , Hyunju Lee

In recent years, we have seen deep learning and distributed representations of words and sentences make impact on a number of natural language processing tasks, such as similarity, entailment and sentiment analysis. Here we introduce a new…

Computation and Language · Computer Science 2018-09-05 Lina Rojas-Barahona , Bo-Hsiang Tseng , Yinpei Dai , Clare Mansfield , Osman Ramadan , Stefan Ultes , Michael Crawford , Milica Gasic

Today, we are seeing an ever-increasing number of clinical notes that contain clinical results, images, and textual descriptions of patient's health state. All these data can be analyzed and employed to cater novel services that can help…

Computation and Language · Computer Science 2021-06-10 Danilo Dessi , Rim Helaoui , Vivek Kumar , Diego Reforgiato Recupero , Daniele Riboni

We apply deep learning-based language models to the task of patient cohort retrieval (CR) with the aim to assess their efficacy. The task of CR requires the extraction of relevant documents from the electronic health records (EHRs) on the…

Information Retrieval · Computer Science 2020-09-14 Sarvesh Soni , Kirk Roberts

Deep learning models have become fundamental tools in drug design. In particular, large language models trained on biochemical sequences learn feature vectors that guide drug discovery through virtual screening. However, such models do not…

Biomolecules · Quantitative Biology 2025-03-28 Joseph D. Clark , Tanner J. Dean , Diwakar Shukla

We study the problem of textual relation embedding with distant supervision. To combat the wrong labeling problem of distant supervision, we propose to embed textual relations with global statistics of relations, i.e., the co-occurrence…

Computation and Language · Computer Science 2018-04-20 Yu Su , Honglei Liu , Semih Yavuz , Izzeddin Gur , Huan Sun , Xifeng Yan

In the past ten years, with the help of deep learning, especially the rapid development of deep neural networks, medical image analysis has made remarkable progress. However, how to effectively use the relational information between various…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Zhihua Liu

Biomedical research now commonly integrates diverse data types or views from the same individuals to better understand the pathobiology of complex diseases, but the challenge lies in meaningfully integrating these diverse views. Existing…

Machine Learning · Computer Science 2023-12-05 Sarthak Jain , Sandra E. Safo

While deep networks have been enormously successful over the last decade, they rely on flat-feature vector representations, which makes them unsuitable for richly structured domains such as those arising in applications like social network…

Machine Learning · Computer Science 2020-01-14 Navdeep Kaur , Gautam Kunapuli , Saket Joshi , Kristian Kersting , Sriraam Natarajan
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