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Magnetic resonance spectroscopy (MRS) is an important technique in biomedical research and it has the unique capability to give a non-invasive access to the biochemical content (metabolites) of scanned organs. In the literature, the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Nima Hatami , Michaël Sdika , Hélène Ratiney

Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M…

Magnetic resonance spectroscopy (MRS) is an established technique for studying tissue metabolism, particularly in central nervous system disorders. While powerful and versatile, MRS is often limited by challenges associated with data…

Quantitative Methods · Quantitative Biology 2024-08-29 Christopher J. Wu , Lawrence S. Kegeles , Jia Guo

Objective: Magnetic Resonance Spectroscopy (MRS) is an important technique for biomedical detection. However, it is challenging to accurately quantify metabolites with proton MRS due to serious overlaps of metabolite signals, imperfections…

Two-dimensional electronic spectroscopy (2DES) has enabled significant discoveries in both biological and synthetic energy-transducing systems. Although deriving chemical information from 2DES is a complex task, machine learning (ML) offers…

Chemical Physics · Physics 2025-03-21 Jonathan D. Schultz , Kelsey A. Parker , Bashir Sbaiti , David N. Beratan

Magnetic resonance imaging (MRI) has revolutionized medical imaging, providing a non-invasive and highly detailed look into the human body. However, the long acquisition times of MRI present challenges, causing patient discomfort, motion…

Medical Physics · Physics 2026-01-16 Mojtaba Safari , Zach Eidex , Chih-Wei Chang , Richard L. J. Qiu , Xiaofeng Yang

Model-driven analysis of biophysical phenomena is gaining increased attention and utility for medical imaging applications. In magnetic resonance imaging (MRI), the availability of well-established models for describing the relations…

Medical Physics · Physics 2023-10-31 Dinor Nagar , Nikita Vladimirov , Christian T. Farrar , Or Perlman

Magnetic resonance imaging (MRI) is a non-invasive imaging modality and provides comprehensive anatomical and functional insights into the human body. However, its long acquisition times can lead to patient discomfort, motion artifacts, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Mojtaba Safari , Zach Eidex , Chih-Wei Chang , Richard L. J. Qiu , Xiaofeng Yang

Magnetic resonance spectroscopy (MRS) is used to quantify metabolites in vivo and estimate biomarkers for conditions ranging from neurological disorders to cancers. Quantifying low-concentration metabolites such as GABA…

Signal Processing · Electrical Eng. & Systems 2026-02-25 Zien Ma , S. M. Shermer , Oktay Karakuş , Frank C. Langbein

Laser absorption spectroscopy (LAS) is a well-established technique for non-intrusive measurement of gas species in combustion and atmospheric environments, but conventional methods struggle with multi-species mixtures under dynamic or…

Optics · Physics 2026-05-05 Mohamed Sy

Nuclear magnetic resonance (NMR) spectroscopy serves as an indispensable tool in chemistry and biology but often suffers from long experimental time. We present a proof-of-concept of application of deep learning and neural network for…

Medical Physics · Physics 2019-05-15 Xiaobo Qu , Yihui Huang , Hengfa Lu , Tianyu Qiu , Di Guo , Tatiana Agback , Vladislav Orekhov , Zhong Chen

Functional MRI (fMRI) is commonly used for interpreting neural activities across the brain. Numerous accelerated fMRI techniques aim to provide improved spatiotemporal resolutions. Among these, simultaneous multi-slice (SMS) imaging has…

Image and Video Processing · Electrical Eng. & Systems 2021-05-11 Omer Burak Demirel , Burhaneddin Yaman , Logan Dowdle , Steen Moeller , Luca Vizioli , Essa Yacoub , John Strupp , Cheryl A. Olman , Kâmil Uğurbil , Mehmet Akçakaya

Magnetic resonance spectroscopy (MRS) is an important clinical imaging method for diagnosis of diseases. MRS spectrum is used to observe the signal intensity of metabolites or further infer their concentrations. Although the magnetic…

Background: Magnetic resonance spectroscopy (MRS) enables non-invasive detection and measurement of biochemicals and metabolites. However, MRS has low signal-to-noise ratio (SNR) when concentrations of metabolites are in the range of the…

Medical Physics · Physics 2023-03-30 Jing Wang , Bing Ji , Yang Lei , Tian Liu , Hui Mao , Xiaofeng Yang

Compressed sensing (CS) is a new signal acquisition paradigm that enables the reconstruction of signals and images from a low number of samples. A particularly exciting application of CS is Magnetic Resonance Imaging (MRI), where CS…

Information Theory · Computer Science 2016-08-17 Samuel Birns , Bohyun Kim , Stephanie Ku , Kevin Stangl , Deanna Needell

High-dimensional hyperspectral imaging (HSI) enables the visualization of ultrafast molecular dynamics and complex, heterogeneous spectra. However, applying this capability to resolve spatially varying vibrational couplings in…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Chi-Jui Ho , Harsh Bhakta , Wei Xiong , Nicholas Antipa

Stimulated Raman scattering (SRS) microscopy is a powerful label-free imaging technique that probes the vibrational response of chemicals with high specificity and sensitivity. High-power, quantum-enhanced SRS microscopes have been recently…

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

This work proposes a method to accelerate the acquisition of high-quality edited magnetic resonance spectroscopy (MRS) scans using machine learning models taking the sample covariance matrix as input. The method is invariant to the number…

Purpose: This study presents a variable resolution (VR) sampling and deep learning reconstruction approach for multi-spectral MRI near metal implants, aiming to reduce scan times while maintaining image quality. Background: The rising use…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Azadeh Sharafi , Nikolai J. Mickevicius , Mehran Baboli , Andrew S. Nencka , Kevin M. Koch
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