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Predictive coding (PC) is an influential computational model of visual learning and inference in the brain. Classical PC was proposed as a top-down generative model, where the brain actively predicts upcoming visual inputs, and inference…

Machine Learning · Computer Science 2025-12-18 Gaspard Oliviers , Mufeng Tang , Rafal Bogacz

Mathematical methods provide useful framework for the analysis and design of complex systems. In newer contexts such as biology, however, there is a need to both adapt existing methods as well as to develop new ones. Using a combination of…

Molecular Networks · Quantitative Biology 2017-12-06 Abhishek Dey , Shaunak Sen

Probabilistic programming is considered as a framework, in which basic components of cognitive architectures can be represented in unified and elegant fashion. At the same time, necessity of adopting some component of cognitive…

Artificial Intelligence · Computer Science 2016-05-05 Alexey Potapov

The generation of comprehensible explanations is an essential feature of modern artificial intelligence systems. In this work, we consider probabilistic logic programming, an extension of logic programming which can be useful to model…

Artificial Intelligence · Computer Science 2023-08-17 Germán Vidal

A framework is presented for a computational theory of probabilistic argument. The Probabilistic Reasoning Environment encodes knowledge at three levels. At the deepest level are a set of schemata encoding the system's domain knowledge.…

Artificial Intelligence · Computer Science 2013-04-05 Kathryn Blackmond Laskey

It has been proposed that populations of neurons process information in terms of probability density functions (PDFs) of analog variables. Such analog variables range, for example, from target luminance and depth on the sensory interface to…

Disordered Systems and Neural Networks · Physics 2007-05-23 M. J. Barber , J. W. Clark , C. H. Anderson

Biological organisms are composed of numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted. Thus, understanding these biochemical processes and their interrelationships is a…

Artificial Intelligence · Computer Science 2014-03-04 Saadat Anwar

The machine learning community has recently put effort into quantized or low-precision arithmetics to scale large models. This paper proposes performing probabilistic inference in the quantized, discrete parameter space created by these…

Machine Learning · Computer Science 2025-08-20 Aleksanteri Sladek , Martin Trapp , Arno Solin

When collaborating with an AI system, we need to assess when to trust its recommendations. If we mistakenly trust it in regions where it is likely to err, catastrophic failures may occur, hence the need for Bayesian approaches for…

Artificial Intelligence · Computer Science 2021-02-23 Federico Cerutti , Lance M. Kaplan , Angelika Kimmig , Murat Sensoy

This manuscript contributes a general and practical framework for casting a Markov process model of a system at equilibrium as a structural causal model, and carrying out counterfactual inference. Markov processes mathematically describe…

Machine Learning · Statistics 2019-11-07 Robert Osazuwa Ness , Kaushal Paneri , Olga Vitek

Affective Computing is a rapidly growing field spurred by advancements in artificial intelligence, but often, held back by the inability to translate psychological theories of emotion into tractable computational models. To address this, we…

Artificial Intelligence · Computer Science 2020-08-03 Desmond C. Ong , Harold Soh , Jamil Zaki , Noah D. Goodman

Probabilistic circuits (PCs) are a unifying representation for probabilistic models that support tractable inference. Numerous applications of PCs like controllable text generation depend on the ability to efficiently multiply two circuits.…

Artificial Intelligence · Computer Science 2025-05-01 Honghua Zhang , Benjie Wang , Marcelo Arenas , Guy Van den Broeck

We present probabilistic neural programs, a framework for program induction that permits flexible specification of both a computational model and inference algorithm while simultaneously enabling the use of deep neural networks.…

Neural and Evolutionary Computing · Computer Science 2016-12-05 Kenton W. Murray , Jayant Krishnamurthy

We present a short introduction into the framework of piecewise deterministic Markov processes. We illustrate the abstract mathematical setting with a series of examples related to dispersal of biological systems, cell cycle models, gene…

Probability · Mathematics 2015-12-08 Ryszard Rudnicki , Marta Tyran-Kaminska

The modelling and analysis of biological systems has deep roots in Mathematics, specifically in the field of Ordinary Differential Equations. Alternative approaches based on formal calculi, often derived from process algebras or term…

A class of analog computers built from large numbers of microscopic probabilistic machines is discussed. It is postulated that such computers are implemented in biological systems as ensembles of protein molecules. The formalism is based on…

Biological Physics · Physics 2008-06-24 Victor Eliashberg

Automation is becoming ubiquitous in all laboratory activities, leading towards precisely defined and codified laboratory protocols. However, the integration between laboratory protocols and mathematical models is still lacking. Models…

Quantitative Methods · Quantitative Biology 2021-11-30 Luca Cardelli , Marta Kwiatkowska , Luca Laurenti

Probabilistic programming is related to a compositional approach to stochastic modeling by switching from discrete to continuous time dynamics. In continuous time, an operator-algebra semantics is available in which processes proceeding in…

Artificial Intelligence · Computer Science 2012-12-05 Eric Mjolsness

While probability theory is normally applied to external environments, there has been some recent interest in probabilistic modeling of the outputs of computations that are too expensive to run. Since mathematical logic is a powerful tool…

Artificial Intelligence · Computer Science 2016-10-10 Scott Garrabrant , Benya Fallenstein , Abram Demski , Nate Soares

Recently, there has been extensive research on the capabilities of biologically plausible algorithms. In this work, we show how one of such algorithms, called predictive coding, is able to perform causal inference tasks. First, we show how…

Machine Learning · Computer Science 2024-06-04 Tommaso Salvatori , Luca Pinchetti , Amine M'Charrak , Beren Millidge , Thomas Lukasiewicz