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We present the construction of molecular force fields for small molecules (less than 25 atoms) using the recently developed symmetrized gradient-domain machine learning (sGDML) approach [Chmiela et al., Nat. Commun. 9, 3887 (2018); Sci.…

Temperature is a fundamental regulator of chemical and biochemical kinetics, yet capturing nonlinear thermal effects directly from experimental data remains a major challenge due to limited throughput and model flexibility. Recent advances…

Quantitative Methods · Quantitative Biology 2025-12-23 Mamoru Saita , Yutaka Hori

We present the implementation of a three-dimensional, second order accurate Godunov-type algorithm for magneto-hydrodynamic (MHD), in the adaptive-mesh-refinement (AMR) cosmological code {\tt CHARM}. The algorithm is based on the full…

Instrumentation and Methods for Astrophysics · Physics 2015-05-27 Francesco Miniati , Daniel F. Martin

Dissipative Particle Dynamics (DPD) is a popular simulation model for investigating hydrodynamic behavior of systems with non-negligible equilibrium thermal fluctuations. DPD employs soft core repulsive interactions between the system…

Statistical Mechanics · Physics 2016-03-23 Oded Farago , Niels Grønbech-Jensen

The high accuracy exhibited by biological information transcription processes is due to kinetic proofreading, i.e., by a mechanism which reduces the error rate of the information-handling process by driving it out of equilibrium. We provide…

Statistical Mechanics · Physics 2015-06-18 Riccardo Rao , Luca Peliti

A new configurational temperature thermostat suitable for molecules with holonomic constraints is derived. This thermostat has a simple set of motion equations, can generate the canonical ensemble in both position and momentum space, acts…

Statistical Mechanics · Physics 2009-11-13 Karl P. Travis , Carlos Braga

Conventional molecular dynamics (MD) simulation approaches, such as $\textit{ab initio}$ MD (AIMD) and empirical force field MD (EFFMD), face significant trade-offs between physical accuracy and computational efficiency. This work presents…

Disordered Systems and Neural Networks · Physics 2026-05-12 Hongyu Yan , Yong Wei , Minghan Chen , Hanning Chen

Nanoparticle surface structural dynamics is believed to play a significant role in regulating functionalities such as diffusion, reactivity, and catalysis but the atomic-level processes are not well understood. Atomic resolution…

The smoothed particle hydrodynamics (SPH) method has been increasingly used to study fluid problems in recent years; but its computational cost can be high if high resolution is required. In this study, an adaptive resolution method based…

Computational Physics · Physics 2019-01-23 Xiufeng Yang , Song-Charng Kong

Dynamic Mode Decomposition (DMD) is an unsupervised machine learning method that has attracted considerable attention in recent years owing to its equation-free structure, ability to easily identify coherent spatio-temporal structures in…

Machine Learning · Computer Science 2022-02-16 Alex Viguerie , Gabriel F. Barros , Malú Grave , Alessandro Reali , Alvaro L. G. A. Coutinho

An important ingredient of any moving-mesh method for fluid-structure interaction (FSI) problems is the mesh deformation technique (MDT) used to adapt the computational mesh in the moving fluid domain. An ideal technique is computationally…

Computational Engineering, Finance, and Science · Computer Science 2020-06-26 Alexander Shamanskiy , Bernd Simeon

Strand displacement and tile assembly systems are designed to follow prescribed kinetic rules (i.e., exhibit a specific time-evolution). However, the expected behavior in the limit of infinite time--known as thermodynamic equilibrium--is…

Emerging Technologies · Computer Science 2017-09-26 David Doty , Trent A. Rogers , David Soloveichik , Chris Thachuk , Damien Woods

We present the dynamics of a thermally bistable medium using one-dimensional numerical calculations, including cooling, heating, thermal conduction, and physical viscosity.We set up a two-phase medium from a thermally unstable one-phase…

Astrophysics · Physics 2009-11-07 Hiroshi Koyama , Shu-ichiro Inutsuka

Turbulent diffuse molecular clouds can exhibit complicated morphologies caused by the interactions among radiation, chemistry, fluids, and fields. We performed full 3D simulations for turbulent diffuse molecular interstellar media,…

Astrophysics of Galaxies · Physics 2024-07-17 Nannan Yue , Lile Wang , Thomas Bisbas , Donghui Quan , Di Li

For nearly the past 30 years, Centroid Molecular Dynamics (CMD) has proven to be a viable classical-like phase space formulation for the calculation of quantum dynamical properties. However, calculation of the centroid effective force…

Chemical Physics · Physics 2022-09-15 Timothy D. Loose , Patrick G. Sahrmann , Gregory A. Voth

In this paper we propose an accurate, and computationally efficient method for incorporating adaptive spatial resolution into weakly-compressible Smoothed Particle Hydrodynamics (SPH) schemes. Particles are adaptively split and merged in an…

Fluid Dynamics · Physics 2022-05-17 Abhinav Muta , Prabhu Ramachandran

In Molecular Dynamics (MD), the forces applied to atoms derive from potentials which describe the energy of bonds, valence angles, torsion angles, and Lennard-Jones interactions of which molecules are made. These de finitions are classic;…

Statistical Mechanics · Physics 2014-01-07 Bernard Monasse , Frédéric Boussinot

The use of probe molecules to extract the local dynamical and structural properties of complex dynamical systems is an age-old technique both in simulations and experiments. A lot of important information which is not immediately accessible…

Soft Condensed Matter · Physics 2021-03-30 Anoop Mutneja , Smarajit Karmakar

We show here that molecular resolution is inherently hybrid in terms of relative separation: If molecules are close to each other, they must be characterized by a fine-grained (geometrically detailed) model, yet if molecules are far from…

Soft Condensed Matter · Physics 2019-03-13 Aviel Chaimovich , Christine Peter , Kurt Kremer

Tight-binding (TB) molecular dynamics (MD) has emerged as a powerful method for investigating the atomic-scale structure of materials --- in particular the interplay between structural and electronic properties --- bridging the gap between…

Materials Science · Physics 2007-05-23 Laurent J Lewis , Normand Mousseau
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