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Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Limited data and low dose constraints are common problems in a variety of tomographic reconstruction paradigms which lead to noisy and incomplete data. Over the past few years sinogram denoising has become an essential pre-processing step…

Low dose computed tomography (LDCT) is desirable for both diagnostic imaging and image guided interventions. Denoisers are openly used to improve the quality of LDCT. Deep learning (DL)-based denoisers have shown state-of-the-art…

Given the potential X-ray radiation risk to the patient, low-dose CT has attracted a considerable interest in the medical imaging field. The current main stream low-dose CT methods include vendor-specific sinogram domain filtration and…

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

This study aimed to propose a denoising method for dynamic contrast-enhanced computed tomography (DCE-CT) perfusion studies using a three-dimensional deep image prior (DIP), and to investigate its usefulness in comparison with total…

Zero-shot denoisers address the dataset dependency of deep-learning-based denoisers, enabling the denoising of unseen single images. Nonetheless, existing zero-shot methods suffer from long training times and rely on the assumption of noise…

Image demosaicking and denoising are the first two key steps of the color image production pipeline. The classical processing sequence has for a long time consisted of applying denoising first, and then demosaicking. Applying the operations…

Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…

In recent years, there has been a growing interest in applying convolutional neural networks (CNNs) to low-level vision tasks such as denoising and super-resolution. Due to the coherent nature of the image formation process, optical…

Low Dose Computed Tomography (LDCT) is clinically desirable due to the reduced radiation to patients. However, the quality of LDCT images is often sub-optimal because of the inevitable strong quantum noise. Inspired by their unprecedent…

The cryo-electron microscopy (Cryo-EM) becomes popular for macromolecular structure determination. However, the 2D images which Cryo-EM detects are of high noise and often mixed with multiple heterogeneous conformations or contamination,…

Objective: There exist several X-ray computed tomography (CT) scanning strategies to reduce a radiation dose, such as (1) sparse-view CT, (2) low-dose CT, and (3) region-of-interest (ROI) CT (called interior tomography). To further reduce…

Supervised learning-based methods yield robust denoising results, yet they are inherently limited by the need for large-scale clean/noisy paired datasets. The use of unsupervised denoisers, on the other hand, necessitates a more detailed…

Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the…

Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…

Deep-learning methods have shown promising performance for low-dose computed tomography (LDCT) reconstruction. However, supervised methods face the problem of lacking labeled data in clinical scenarios, and the CNN-based unsupervised…

Rb-82 dynamic cardiac PET imaging is widely used for the clinical diagnosis of coronary artery disease (CAD), but its short half-life results in high noise levels that degrade dynamic frame quality and parametric imaging. The lack of paired…

Image denoising is a classical problem in low level computer vision. Model-based optimization methods and deep learning approaches have been the two main strategies for solving the problem. Model-based optimization methods are flexible for…

The presence of noise is common in signal processing regardless the signal type. Deep neural networks have shown good performance in noise removal, especially on the image domain. In this work, we consider deep neural networks as a…