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Array comparative genomic hybridization(CGH) is a high resolution technique to assess DNA copy number variation. Identifying breakpoints where copy number changes will enhance the understanding of the pathogenesis of human diseases, such as…

Applications · Statistics 2012-01-26 Bin Zhu , Jeremy M. G. Taylor , Peter X. -K. Song

Introducing accelerated reconstruction algorithms into clinical settings requires measures of uncertainty quantification that accurately assess the relevant uncertainty introduced by the reconstruction algorithm. Many currently deployed…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Luca L. C. Trautmann , Peter A. Wijeratne , Itamar Ronen , Ivor J. A. Simpson

Randomization, as a key technique in clinical trials, can eliminate sources of bias and produce comparable treatment groups. In randomized experiments, the treatment effect is a parameter of general interest. Researchers have explored the…

Methodology · Statistics 2023-12-05 Fuyi Tu , Wei Ma , Hanzhong Liu

Early detection and analysis of calcifications in mammogram images is crucial in a breast cancer diagnosis workflow. Management of calcifications that require immediate follow-up and further analyzing its benignancy or malignancy can result…

Image and Video Processing · Electrical Eng. & Systems 2022-12-12 Adarsh Bhandary Panambur , Prathmesh Madhu , Andreas Maier

Chemical Exchange Saturation Transfer (CEST) MRI enables molecular-level visualization of low-concentration metabolites by leveraging proton exchange dynamics. However, its clinical translation is hindered by inherent challenges: spatially…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Chu Chen , Aitor Artola , Yang Liu , Se Weon Park , Raymond H. Chan , Jean-Michel Morel , Kannie W. Y. Chan

Continuous biomarkers are common for disease screening and diagnosis. To reach a dichotomous clinical decision, a threshold would be imposed to distinguish subjects with disease from non-diseased individuals. Among various performance…

Methodology · Statistics 2021-04-21 Ziyi Li , Yijuan Huang , Dattatraya Patil , Martin G. Sanda

An emerging area of research is the study of macroscale migration patterns as a network of nodes that represent places (e.g., countries, cities, and rural areas) and edges that encode migration ties that connect those places. In this…

Social and Information Networks · Computer Science 2020-05-28 Valentin Danchev , Mason A. Porter

Unsupervised registration strategies bypass requirements in ground truth transforms or segmentations by optimising similarity metrics between fixed and moved volumes. Among these methods, a recent subclass of approaches based on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Benjamin Billot , Ramya Muthukrishnan , Esra Abaci-Turk , P. Ellen Grant , Nicholas Ayache , Hervé Delingette , Polina Golland

The development of cancer is largely driven by the gain or loss of subsets of the genome, promoting uncontrolled growth or disabling defenses against it. Identifying genomic regions whose DNA copy number deviates from the normal is…

Graph-SLAM is a well-established algorithm for constructing a topological map of the environment while simultaneously attempting the localisation of the robot. It relies on scan matching algorithms to align noisy observations along robot's…

Robotics · Computer Science 2022-01-20 Giorgio Iavicoli , Claudio Zito

We introduce a graphical method originating from the computer graphics domain that is used for the arbitrary and intuitive placement of cells over a two-dimensional manifold. Using a bitmap image as input, where the color indicates the…

Neural and Evolutionary Computing · Computer Science 2018-03-23 Nicolas P. Rougier

Several modern genomic technologies, such as DNA-Methylation arrays, measure spatially registered probes that number in the hundreds of thousands across multiplechromosomes. The measured probes are by themselves less interesting…

Applications · Statistics 2016-11-16 John Nagorski , Genevera I. Allen

Anomaly localization in images -- identifying regions that deviate from normal patterns -- is vital in applications such as medical diagnosis and industrial inspection. A recent trend is the use of image generation models in anomaly…

Machine Learning · Statistics 2026-04-28 Teruyuki Katsuoka , Tomohiro Shiraishi , Daiki Miwa , Vo Nguyen Le Duy , Ichiro Takeuchi

Multi-frequency subspace migration imaging technique are usually adopted for the non-iterative imaging of unknown electromagnetic targets such as cracks in the concrete walls or bridges, anti-personnel mines in the ground, etc. in the…

Mathematical Physics · Physics 2014-12-23 Won-Kwang Park

Mixup is a data-dependent regularization technique that consists in linearly interpolating input samples and associated outputs. It has been shown to improve accuracy when used to train on standard machine learning datasets. However,…

Machine Learning · Computer Science 2022-01-13 Raphael Baena , Lucas Drumetz , Vincent Gripon

Unsupervised image transfer enables intra- and inter-modality image translation in applications where a large amount of paired training data is not abundant. To ensure a structure-preserving mapping from the input to the target domain,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-05 Christoph Angermann , Markus Haltmeier , Ahsan Raza Siyal

We propose a new test case prioritization technique that combines both mutation-based and diversity-based approaches. Our diversity-aware mutation-based technique relies on the notion of mutant distinguishment, which aims to distinguish one…

Software Engineering · Computer Science 2018-01-24 Donghwan Shin , Shin Yoo , Mike Papadakis , Doo-Hwan Bae

Stochastic models of surface growth are usually based on randomly choosing a substrate site to perform iterative steps, as in the etching model [1]. In this paper I modify the etching model to perform sequential, instead of random,…

Statistical Mechanics · Physics 2017-07-19 Bernardo A. Mello

With the advent of digital scanners and deep learning, diagnostic operations may move from a microscope to a desktop. Hematoxylin and Eosin (H&E) staining is one of the most frequently used stains for disease analysis, diagnosis, and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Shikha Dubey , Tushar Kataria , Beatrice Knudsen , Shireen Y. Elhabian

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

Biological Physics · Physics 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano