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Artificial Intelligence (AI) and Machine-Learning (ML) models have been increasingly used in medical products, such as medical device software. General considerations on the statistical aspects for the evaluation of AI/ML-enabled medical…

Methodology · Statistics 2023-03-10 Feiming Chen , Hong Laura Lu , Arianna Simonetti

Identity-based code signing enables software developers to digitally sign their code using cryptographic keys. This key is then linked to an identity (e.g., through an identity provider), allowing signers to verify both the code's origin…

Cryptography and Security · Computer Science 2025-12-24 Chinenye Okafor , James C. Davis , Santiago Torres-Arias

Given the sensitive nature of health data, security and privacy in e-health systems is of prime importance. It is crucial that an e-health system must ensure that users remain private - even if they are bribed or coerced to reveal…

Cryptography and Security · Computer Science 2018-08-28 Naipeng Dong , Hugo Jonker , Jun Pang

Clinicians often face workflow problems that are perceived as either too bespoke or low stakes to attract commercial attention. Historically, most do not have the technical knowledge to address these problems, but the recent emergence of…

Human-Computer Interaction · Computer Science 2026-04-28 Ariel Yuhan Ong , Iain Livingstone , Caroline Kilduff , Mertcan Sevgi , David A Merle , Eden Ruffell , Pearse A Keane , Fares Antaki

The use of embedded software is advancing in modern medical devices, so does its capabilities and complexity. This paradigm shift brings many challenges such as an increased rate of medical device failures due to software faults. In this…

Software Engineering · Computer Science 2017-06-21 Atif Mashkoor , Miklos Biro

Intermediate-scale quantum devices are becoming more reliable, and may soon be harnessed to solve useful computational tasks. At the same time, common classical methods used to verify their computational output become intractable due to a…

Quantum Physics · Physics 2023-07-03 Johannes Knörzer , Daniel Malz , J. Ignacio Cirac

In pediatrics, patients, caregivers, and clinicians share responsibility for health decisions, but limited collaboration can undermine outcomes. We conducted a qualitative study examining decision-makers perceptions toward collaborative…

Human-Computer Interaction · Computer Science 2026-05-22 Ray-Yuan Chung , Athena Ortega , Zixuan Xu , Daeun Yoo , Jaime Snyder , Wanda Pratt , Aaron Wightman , Ryan Hutson , Cozumel Pruette , Ari Pollack

Multi-particle interference is a key resource for quantum information processing, as exemplified by Boson Sampling. Hence, given its fragile nature, an essential desideratum is a solid and reliable framework for its validation. However,…

The storage and manipulation of digital images and the analysis of the information held in those images are essential requirements for next-generation medical information systems. The medical community has been exploring collaborative…

Databases · Computer Science 2007-05-23 D Rogulin , F Estrella , T Hauer , R McClatchey , T Solomonides

"DHEAL-COM - Digital Health Solutions in Community Medicine" is a research and technology project funded by the Italian Department of Health for the development of digital solutions of interest in proximity healthcare. The activity within…

The medical device products at the European Union market must be safe and effective. To ensure this, medical device manufacturers must comply to the new regulatory requirements brought by the Medical Device Regulation (MDR) and the In Vitro…

Cryptography and Security · Computer Science 2021-03-12 Tuomas Granlund , Juha Vedenpää , Vlad Stirbu , Tommi Mikkonen

As healthcare systems increasingly adopt advanced wireless networks and connected devices, securing medical applications has become critical. The integration of Internet of Medical Things devices, such as robotic surgical tools, intensive…

Machine Learning · Computer Science 2025-05-21 Navneet Kaur , Lav Gupta

Context: The complexity of modern safety-critical systems in industries keep on increasing due to the rising number of features and functionalities. This calls for formal methods in order to entrust confidence in such systems. Nevertheless,…

Software Engineering · Computer Science 2021-08-17 Arut Prakash Kaleeswaran , Arne Nordmann , Thomas Vogel , Lars Grunske

Critical software systems face stringent requirements in safety, security, and reliability due to the circumstances surrounding their operation. Safety and security have progressively gained importance over the years due to the integration…

Software Engineering · Computer Science 2015-12-16 Julio Escribano-Barreno , Marisol García-Valls

The increasing popularity of machine learning approaches and the rising awareness of data protection and data privacy presents an opportunity to build truly secure and trustworthy healthcare systems. Regulations such as GDPR and HIPAA…

Cryptography and Security · Computer Science 2020-11-17 Goutham Ramakrishnan , Aditya Nori , Hannah Murfet , Pashmina Cameron

The use of machine learning systems in clinical routine is still hampered by the necessity of a medical device certification and/or by difficulty to implement these systems in a clinic's quality management system. In this context, the key…

Medical Physics · Physics 2022-10-18 Lorenzo Mercolli , Axel Rominger , Kuangyu Shi

Background: Data errors are a common challenge in machine learning (ML) projects and generally cause significant performance degradation in ML-enabled software systems. To ensure early detection of erroneous data and avoid training ML…

Software Engineering · Computer Science 2021-03-09 Lucy Ellen Lwakatare , Ellinor Rånge , Ivica Crnkovic , Jan Bosch

Summary: More sophisticated models are needed to address problems in bioscience, synthetic biology, and precision medicine. To help facilitate the collaboration needed for such models, the community developed the Simulation Experiment…

Ultrasound (US) machines display images on a built-in monitor, but routine transfer to hospital systems relies on DICOM. We propose a fully automatic method to generate labeled data that can be used to train a screen detector model, and a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Alberto Gomez , Jorge Oliveira , Ramon Casero , Agis Chartsias

Image registration is a key task in medical imaging applications, allowing to represent medical images in a common spatial reference frame. Current approaches to image registration are generally based on the assumption that the content of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Riccardo Taiello , Melek Önen , Francesco Capano , Olivier Humbert , Marco Lorenzi