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In this paper, we address the efficient numerical solution of linear and quadratic programming problems, often of large scale. With this aim, we devise an infeasible interior point method, blended with the proximal method of multipliers,…
The efficient solution of moderately large-scale linear systems arising from the KKT conditions in optimal control problems (OCPs) is a critical challenge in robotics. With the stagnation of Moore's law, there is growing interest in…
Generating a novel and optimized molecule with desired chemical properties is an essential part of the drug discovery process. Failure to meet one of the required properties can frequently lead to failure in a clinical test which is costly.…
This paper is devoted to GPU kernel optimization and performance analysis of three tensor-product operators arising in finite element methods. We provide a mathematical background to these operations and implementation details. Achieving…
This paper concerns the preconditioning technique for discrete systems arising from time-harmonic Maxwell equations with absorptions, where the discrete systems are generated by N\'ed\'elec finite element methods of fixed order on meshes…
This paper is devoted to continuous and discrete adjoint-based optimization approaches for optimal control problems governed by an important class of Nonlinear Coupled Anisotropic Convection-Diffusion Chemotaxis-type System (NCACDCS). This…
This paper is devoted to global existence of weak solutions to the following degenerate kinetic model of chemotaxis \begin{equation} \begin{cases}\label{chemo0} u_t=\Delta (\gamma (v)u) \tau v_{t}=\Delta v-v+u \end{cases} \end{equation}in a…
Optimal transport problems pose many challenges when considering their numerical treatment. We investigate the solution of a PDE-constrained optimisation problem subject to a particular transport equation arising from the modelling of image…
We consider the numerical solution of large scale time-harmonic Maxwell equations. To this day, this problem remains difficult, in particular because the equations are neither Hermitian nor semi-definite. Our approach is to compare…
The existence of generalised global supersolutions with a control upon the total muss is established for the parabolic-parabolic Keller-Segel system with logarithmic sensitivity for any space dimension. It is verified that smooth…
Keller-Segel systems are a set of nonlinear partial differential equations used to model chemotaxis in biology. In this paper, we propose two alternating direction implicit (ADI) schemes to solve the 2D Keller-Segel systems directly with…
Chemical reactions modeled by ordinary differential equations are finite-dimensional dissipative dynamical systems with multiple time-scales. They are numerically hard to tackle -- especially when they enter an optimal control problem as…
First-order optimization solvers, such as the Fast Gradient Method, are increasingly being used to solve Model Predictive Control problems in resource-constrained environments. Unfortunately, the convergence rate of these solvers is…
We present a data-driven algorithm for efficiently computing stochastic control policies for general joint chance constrained optimal control problems. Our approach leverages the theory of kernel distribution embeddings, which allows…
We shall propose and analyze some new preconditioners for the saddle-point systems arising from the edge element discretization of the time-harmonic Maxwell equations in three dimensions. We will first consider the saddle-point systems with…
The discontinuous Galerkin time-stepping method has many advantageous properties for solving parabolic equations. However, it requires the solution of a large nonsymmetric system at each time-step. This work develops a fully robust and…
The Virtual Element Method (VEM) is a new family of numerical methods for the approximation of partial differential equations, where the geometry of the polytopal mesh elements can be very general. The aim of this article is to extend the…
The aim of this paper is to analyze a model for chemotaxis based on a local sensing mechanism instead of the gradient sensing mechanism used in the celebrated minimal Keller-Segel model. The model we study has the same entropy as the…
In the present review we focus on the chemotaxis-consumption model $\partial_t u - \Delta u = - \nabla \cdot (u \nabla v)$ and $\partial_t v - \Delta v = - u^s v$ in $(0,T) \times \Omega$, for any fixed $s \geq 1$, endowed with isolated…
We study the stationary Keller--Segel chemotaxis models with logistic cellular growth over a one-dimensional region subject to the Neumann boundary condition. We show that nonconstant solutions emerge in the sense of Turing's instability as…